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11 Possible Causes for Facial Swelling, Supraclavicular Fat Pads, Weight Gain

  • Cushing's Disease

    Common clinical signs and symptoms include weight gain, hypertension, and osteoporosis.[ncbi.nlm.nih.gov] Individuals with Cushing syndrome can develop moon facies, facial plethora, supraclavicular fat pads, buffalo hump, truncal obesity, and purple striae, as shown in the image[emedicine.medscape.com] The most common symptoms in adults are weight gain (especially in the trunk, and often not accompanied by weight gain in the arms and legs), high blood pressure (hypertension[pituitarysociety.org]

  • Adrenal Cortex Hormone

    Physicians carefully restrict the number of corticosteroid injections because, over time, they can cause weight gain, osteoporosis (bone degeneration), facial swelling and[laserspineinstitute.com] Too much cortisol from any cause leads to Cushing’s syndrome; the symptoms and signs of which include redistribution of fat to the face, upper back and abdomen, weight gain[csrf.net] ), impotence and sometimes swelling of the breasts Those cancers that don't make any hormones might not cause symptoms until they are quite advanced.[cancerresearchuk.org]

  • Cushing Syndrome

    Features more specific to Cushing's syndrome include proximal muscle weakness, supraclavicular fat pads, facial plethora, violaceous striae, easy bruising, and premature osteoporosis[bestpractice.bmj.com] Despite being rare in clinical practice, in a child with weight gain, hirsuitism and growth failure the diagnosis must be considered.[ncbi.nlm.nih.gov] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org]

  • Iatrogenic Cushing's Disease

    Patients with ICS due to various etiologies have presented with a spectrum of signs and symptoms ranging from excessive weight gain and growth delay to posterior cervical[pediatrics.aappublications.org] Common: centripetal obesity with dorsocervical and supraclavicular fat pads, facial plethora and "moon face," fatigue, hyperglycemia, hypertension, mood lability, easy bruisability[hopkinsguides.com] Individuals with Cushing syndrome can develop moon facies, facial plethora, supraclavicular fat pads, buffalo hump, truncal obesity, and purple striae, as shown in the image[emedicine.medscape.com]

  • Obesity

    Many pharmaceutical drugs can cause weight gain as a side effect ( 10 ). For example, antidepressants have been linked to modest weight gain over time ( 11 ).[healthline.com] Whether an association exists between fast food consumption and weight gain is unclear.[ncbi.nlm.nih.gov] Whether an association exists between SSB intake and weight gain is unclear.[ncbi.nlm.nih.gov]

  • Adrenal Cortical Adenoma

    Cushing syndrome commonly presents with hypertension, weight gain, diabetes, striae or truncal obesity, all of which can be consistent with pregnancy in women without Cushing[ncbi.nlm.nih.gov] ), impotence and sometimes swelling of the breasts Those cancers that don't make any hormones might not cause symptoms until they are quite advanced.[cancerresearchuk.org] The association with facial rounding (“moon face”) and supraclavicular and dorsocervical fat pads (“buffalo hump”) is less strong as these can be seen in obesity from other[cancertherapyadvisor.com]

  • Cortisone

    […] esophagitis pancreatitis elevated alanine transaminase ( ALT , SGPT ) elevated aspartate transaminase ( AST , SGOT ) elevated alkaline phosphatase delayed wound healing facial[rxlist.com] Abstract Cushing's syndrome invariably presents with a classical phenotype comprising central adiposity, prominence of dorsal, supraclavicular and temporal fat pads, bruising[ncbi.nlm.nih.gov] With higher doses and frequent shots, potential side effects include: Thinning of the skin Easy bruising Weight gain Puffiness of the face Higher blood pressure Cataract formation[webmd.com]

  • Mixed Functioning Pituitary Adenoma

    Too much of this hormone causes weight gain, particularly in the body’s trunk.[cancer.net] Clinical Findings of Acromegaly Symptoms and signs at presentation Overall prevalence (%) Facial change, acral enlargement, and soft-tissue swelling 100 Excessive sweating[slideshare.net] Symptoms of severe hypopituitarism include: Loss of appetite Weight loss or weight gain Fatigue Decreased energy Decreased mental function Dizziness Changes in hormonal function[pituitary.ucla.edu]

  • Follicular Thyroid Carcinoma

    No history of loss of appetite, tremor, alopecia, weight gain, heat or cold intolerance and patient was euthyroid on thyroid function test.[thetrp.net] METHOD: A 59-year-old woman with a five-year history of a large and mainly right-sided cervical mass presented with dyspnea, unilateral arm swelling, facial flushing, and[ncbi.nlm.nih.gov] At follow-up, 2 months after surgery, physical examination revealed facial plethora, supraclavicular fat pads, gynecomastia, hepatomegaly, and edema of the extremities.[karger.com]

  • Mifepristone

    The patient's striae, weight gain, and buffalo hump markedly improved, and further bone loss was halted.[ncbi.nlm.nih.gov] At presentation, the patient complained of facial swelling, difficulty swallowing, muscle weakness, and difficulty standing, as well as generalized severe fatigue and irritability[pediatrics.aappublications.org] The long-term aim of this clinical trial is to evaluate the ability of mifepristone to reverse or improve glucose intolerance, dyslipidemia, hypertension and weight gain.[clinicaltrials.gov]

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