Create issue ticket

14 Possible Causes for Facial Wrinkles, Hypertrichosis of Eyebrows, Single Transverse Palmar Crease

  • Opitz-Kaveggia Syndrome

    Single transverse palmar creases and short hands and fingers have been less commonly observed in affected individuals [ Risheg et al 2007 ].[ncbi.nlm.nih.gov] […] fullness, a wide mouth with full lips, and coarse facial features as well as fifth fingernail hypoplasia, absence of terminal phalanges, hypertrichosis, developmental delay[karger.com] […] umbilical artery, single transverse palmar creases, and hypotonia.[nature.com]

  • Autosomal Dominant Prognathism

    Bilateral cleft lip Median cleft lip Aplasia cutis congenita Preaxial polydactyly Premature graying of hair Non-midline cleft lip Thin toenail Coarse facial features Joint[mendelian.co] transverse palmar crease Short neck Sparse hair Dry skin Nevus High forehead Dolichocephaly Hip dislocation Coloboma Prominent nasal bridge Hypoplastic fingernail Nystagmus[mendelian.co] […] congenita terminalis (thick scalp hair extending onto the forehead with generalized increased body hair) associated with a typical acromegaloid facial appearance (thick eyebrows[mendelian.co]

  • Autosomal Dominant Mental Retardation Type 21

    In complete form it can be found as follows: fingers in hands and feet widened and elongated, arms and legs with cylindrical appearance, gross facial traits, skin wrinkles[scielo.org.co] transverse palmar creases Slow growth; congenital heart defect; thyroid dysfunction; developmental delay, especially speech Chromosome analysis in all patients; chromosome[aafp.org] […] that grow together (synophrys); long, curly eyelashes; and/or excessive hair growth on various areas of the body (hypertrichosis).[rarediseases.org]

  • Pfeiffer-Palm-Teller Syndrome

    […] appearance Varicose veins Palmoplantar cutis gyrata Abnormality of primary teeth Facial wrinkling Elbow dislocation Phalangeal dislocation Testicular torsion Short forearm[mendelian.co] transverse palmar crease Cafe-au-lait spot Otitis media Poor suck Recurrent otitis media Pulmonary arterial hypertension Dental crowding Depressivity Gait disturbance Ataxia[mendelian.co] High myopia Sparse scalp hair Wide nose Thin skin Sparse and thin eyebrow Bowing of the long bones Arthrogryposis multiplex congenita Elbow flexion contracture Accelerated[mendelian.co]

  • Char Syndrome

    Overall, the face is broad and long, and the facial features are sometimes described as " coarse ."[ghr.nlm.nih.gov] The syndrome may also include various dermatoglyphics , including transverse flexion creases, distal axial triradius, increased whorls and arches on digits and a single palmar[en.wikipedia.org] At birth, the hair on the face may be abnormally thick (hypertrichosis) but thins out over time.[ghr.nlm.nih.gov]

  • Pili Torti - Onychodysplasia Syndrome

    The teeth that are present are frequently small and pointed.Hypohidrotic ectodermal dysplasia is associated with distinctive facial features including a prominent forehead[icdlist.com] Additional features may include single palmar transverse crease, palmoplantar keratoderma, and nail grooving (summary by Limova et al., 1993 ).[mendelian.co] […] of the medial part of the eyebrows White forelock Heterochromia iridis Deafmutism 26 Nervous System Disorders  — Cerebral palsy — Muscular dystrophy — Myoclonic epilepsy[slideplayer.com]

  • Blepharophimosis - Intellectual Disability Syndrome Type Verloes

    These compensatory mechanisms result in a characteristic facial appearance.[rarediseases.org] transverse palmar creases Abnormality of dental enamel Sparse eyelashes Abnormal dermatoglyphics Palmoplantar hyperkeratosis Aplasia/Hypoplasia of the eyebrow Abnormality[mendelian.co] Confluent eyebrows with hypertrichosis of the medial portions (synophrys) are present in 85% of patients with WS1 and in 25% of patients with WS2.[emedicine.medscape.com]

  • Baraitser Syndrome

    Facial skin was coarse and wrinkled. Examination of the mucosa and nails revealed no abnormality.[ijpd.in] transverse palmar crease Intestinal malrotation Premature birth Growth hormone deficiency Fine hair Hypoglycemia Macrocephaly Frontal bossing Behavioral abnormality Pes planus[mendelian.co] At birth, the hair on the face may be abnormally thick (hypertrichosis) but thins out over time.[ghr.nlm.nih.gov]

  • Autosomal Dominant Mental Retardation Type 5

    In complete form it can be found as follows: fingers in hands and feet widened and elongated, arms and legs with cylindrical appearance, gross facial traits, skin wrinkles[scielo.org.co] transverse palmar creases Slow growth; congenital heart defect; thyroid dysfunction; developmental delay, especially speech Chromosome analysis in all patients; chromosome[aafp.org] […] that grow together (synophrys); long, curly eyelashes; and/or excessive hair growth on various areas of the body (hypertrichosis).[rarediseases.org]

  • Eyebrow Duplication - Syndactyly Syndrome

    Flg. 2 Facial features showing: A - Partial duplication of eyebrows; B - LOW frontal hair line, long eyelashes; C - Excessive wrinkling of periorbital skin when closing the[docslide.com.br] transverse palmar crease Brachydactyly Nevus Cataract Preauricular skin furrow Torticollis Prominent scrotal raphe Prominent umbilicus Downturned corners of mouth Alacrima[mendelian.co] , microcephaly, broad thumbs and hallux which are often angulated, hyper-extensive joints, small tilted pelvis, hypertrichosis, and undescended testes. [2] Current literature[faoj.org]