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133 Possible Causes for Factor IX Decreased

  • Hemophilia

    Abstract In cirrhotic hemophilia patients bleeding from esophageal varices is a serious clinical condition due to congenital deficiency of clotting factors VIII or IX, decreased[ncbi.nlm.nih.gov] VIII or IX administration indications relavent factor is administered for Hemophilia A (Factor VIII) and B (Factor IX) estabilished bleed with decreased factor VIII and IX[orthobullets.com] Hemophilia B (Christmas Disease) This type is caused by a lack or decrease of clotting factor IX.[web.archive.org]

  • Acquired Hemophilia

    The autoantibody against factor VIII in a titer of 121 Bethesda Units/ml (BU/ml) and decreased factor VIII activity to 2% (norm 50-150%) with normal plasma concentration of[ncbi.nlm.nih.gov] […] factor IX.[ncbi.nlm.nih.gov]

  • Hemophilia B

    She was demonstrated to have moderately decreased factor IX levels (factor IX:C, 1.5 units/dl; factor IX:Ag, 2.2 units/dl).[ncbi.nlm.nih.gov] George notes, "Our goal in this trial was to evaluate the safety of the gene therapy product and secondarily, to determine if we could achieve levels of factor IX that could[sciencedaily.com] A rise in factor IX inhibitor level was observed.[ncbi.nlm.nih.gov]

  • Osteoporosis

    These drugs work by interfering with the γ-carboxylation of glutamic acid (Glu) residues on clotting factors II, VII, IX, and X.[doi.org] Warfarin and other vitamin K antagonists are prescribed to millions of people worldwide to decrease their risk of clotting.[doi.org]

  • Obstructive Jaundice

    II, VII, IX, X Vitamin K is fat soluble, therefore is not absorbed due to decreased bile in the GI tract.[almostadoctor.co.uk] […] abscesses Need parenteral antibiotics and biliary decompression Operative mortality in elderly of up to 20% Clotting disorders Vitamin K required for gamma-carboxylation of Factors[almostadoctor.co.uk]

  • Coagulation Abnormalities

    Factors I, V, VIII:C, IX, and XI have all been reported as being elevated and implicated in hypercoagulability in patients with neoplasms.[ncbi.nlm.nih.gov] The same molecular derangement occurs with factors VII, IX, and X.31 Clinical Features and Diagnosis Deficiency of vitamin K, which decreases levels of prothrombin and factors[what-when-how.com] Increased platelet turnover and decreased survival have been noted in patients with disseminated tumors.[ncbi.nlm.nih.gov]

  • Liver Cirrhosis

    A) and IX (in hemophilia B), decreased clotting factor II, VII, IX, X synthesis in the course of chronic liver disease and hipersplenic thrombocytopenia.[ncbi.nlm.nih.gov] If present, cholestasis causes decreased vitamin K absorption, leading to reduced hepatic production of factors II, VII, IX and X.[patient.info] INTRODUCTION: Bleeding from esophageal varices is a serious clinical condition in hemophilia patients due to congenital deficiency or lack of clotting factors VIII (in hemophilia[ncbi.nlm.nih.gov]

  • Thrombophlebitis

    factors II, VII, IX, X, increase adherence, Platelets, decreased activity fibrinolytic) and trauma that occurs during labor that facilitates intrauterine infection, inflammation[omicsonline.org] The pathogenesis of TVO is explained by the triad of Virchow and the unique conditions of hemostasis occurring during the postpartum period (decreased protein S, increased[omicsonline.org]

  • Deep Vein Thrombosis

    The increase in procoagulant activity is a result of an increase in plasma levels of factors V, VII, VIII, IX, and X and fibrinogen. 74 Finally, increases in levels of plasminogen[doi.org] […] activator inhibitor-1 and -2 activity and a decrease in tissue plasminogen activator lead to a hypofibrinolytic state.[doi.org] The decrease in anticoagulant activity is mainly due to a decrease in protein S concentration and an increase in activated protein C resistance.[doi.org]

  • Portal Cirrhosis

    If present, cholestasis causes decreased vitamin K absorption, leading to reduced hepatic production of factors II, VII, IX and X.[patient.info] Coagulopathy results from decreased hepatic production of coagulation factors.[patient.info] Thrombocytopenia is usually secondary to hypersplenism and decreased levels of thrombopoietin.[patient.info]

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