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274 Possible Causes for Factor V Leiden Mutation, Fatigue

  • Vein Disorder

    Ruth Costner I came to Vein Specialists of the Carolinas with a large amount of varicose veins, ankle swelling, constant leg fatigue, and pain.[veinscarolina.com] It is the basis for the development of varicose veins, and can lead to symptoms such as pain, swelling, swollen limbs, leg heaviness and fatigue, skin changes and skin ulcers[veinfocus.com] Many people with varicose veins experience pain, swelling, heaviness, and fatigue in their legs.[veinclinics.com]

  • Liver Cirrhosis

    The coincidence in a given patient of prothrombotic mutations, such as factor V Leiden or PAI-1 polymorphisms, can accelerate the fibrogenetic process.[ncbi.nlm.nih.gov] We report here the case of a 58-year-old male presented with atypical chest pain, dyspnea and fatigue, with a medical history of liver cirrhosis and undergoing treatment with[ncbi.nlm.nih.gov] In the presented case, the authors describe an obese middle-aged man that presented to the emergency department for persistent oedema, scleral icterus and fatigue.[ncbi.nlm.nih.gov]

  • Myocardial Infarction

    She denied any chest pain, shortness of breath, fatigue, lightheadedness, palpitations, nausea or diaphoresis. Her initial laboratory Troponin I resulted 35.9 ng/mL.[ncbi.nlm.nih.gov] Factor V Leiden, JAK 2 mutation, prothrombin gene mutation, and tests for paroxysmal nocturnal hemoglobinuria (PNH) were negative.[ncbi.nlm.nih.gov] Fifty days after PCI the patient experienced progressive fatigue and chest pain with haemodynamic instability.[ncbi.nlm.nih.gov]

  • Pulmonary Embolism

    We present an 88-year-old female with dyspnea and fatigue, which became increasingly worse over a month in the absence of medication. Her weight was 64 kg.[ncbi.nlm.nih.gov] The tests will look for possible inherited defects in your clotting system, such as: Factor V Leiden mutation (seen in up to 40% of cases) Increased factor VIII Imaging tests[uvahealth.com] C deficiency, protein S deficiency, factor V (Leiden mutation), malignancy, severe burns.[medical-dictionary.thefreedictionary.com]

  • Migraine

    .: Occurrence of factor V Leiden mutation (Arg506Gin) and anticardiolipin antibodies in migraine patients. Neurol Sci 2002, 22 :455–458.[dx.doi.org] However, the pathophysiological concept behind this term is not undisputed and typical migraine premonitory symptoms such as fatigue and yawning, but also a typical association[ncbi.nlm.nih.gov] Adverse events included paresthesia, fatigue, nausea, and anorexia.[aafp.org]

  • Atrial Fibrillation

    But you may feel Palpitations -- an abnormal rapid heartbeat Shortness of breath Weakness or difficulty exercising Chest pain Dizziness or fainting Fatigue Confusion AF can[medlineplus.gov] She had atrial fibrillation and heterozygosity for both factor V Leiden and methylenetetrahydrofolate reductase C677T mutation, thus creating resistance to activated protein[ncbi.nlm.nih.gov] Symptoms include irregular pulse, palpitations, shortness of breath and fatigue. Inova offers leading expertise in all aspects of atrial fibrillation management.[inovaheart.org]

  • Cor Pulmonale

    Symptoms of CPM include fatigue, lethargy, dypsnoea on exertion, tachypnoea, chest pain, exertional syncope, dyspnoea at rest, nonproductive cough, haemoptysis, hoarseness[link.springer.com] Inherited conditions that affect clotting are: Factor V Leiden thrombophilia Prothrombin G20210A mutation Other rare conditions, such as protein C, protein S, and antithrombin[nlm.nih.gov] Symptoms include chronic cough, shortness of breath on exertion, fatigue, and other signs of oxygen lack to the body tissues.[curlie.org]

  • Varicose Veins

    The types detected were: factor V Leiden (31/60, i.e. 51.6%), prothrombin mutation (2/60, i.e. 3.3%), MTHFR mutation (23/60, i.e. 38.3%), antiphospholipid antibodies (5/60[ncbi.nlm.nih.gov] Clinical presentation includes lower extremity pain, fatigue, itching and/or heaviness, which often worsen with prolonged standing, associated with dilated tortuous veins.[bestpractice.bmj.com] Enhancement by factor V Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen.[dx.doi.org]

  • Occult Malignancy

    Holzner B, Kemmler G, Greil R, Kopp M, Zeimet A, Raderer M, Hejna M, Zochbauer S, Krajnik G, Huber H: The impact of hemoglobin levels on fatigue and quality of life in cancer[karger.com] […] in pregnancy Cancer metastatic to bone Cancer metastatic to ovary Cancer metastatic to parotid gland Cancer metastatic to vagina Cancer of unknown primary Cancer related fatigue[icd10data.com] Inherited hypercoagulable states: The most frequent causes of an inherited hypercoagulable state are the factor V Leiden mutation and the prothrombin gene mutation, accounting[the-hospitalist.org]

  • Behçet Disease

    We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 13, 2019[patientslikeme.com] The investigation of predisposition to thrombosis revealed heterozygous factor V Leiden mutation along with the high lipoprotein(a) level.[ncbi.nlm.nih.gov] […] may be accompanied by cold pain The sores are pale red The sores tend to grow hollow Dry, rough, painful eyes A somber, white facial complexion Dizziness Head distention Fatigue[americandragon.com]

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