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184 Possible Causes for Factor V Leiden Mutation, Leg Swelling

  • Vein Disorder

    Swelling of the leg is a further sign that damaged or diseased vein valves are not functioning properly.[cvvcenters.com] The symptoms include leg swelling, redness, itching and pain.[nehoustonveincenter.com] Left Untreated, Venous Reflux Can Progress to Other Conditions Leg Swelling Swelling of the leg is a further sign that damaged or diseased vein valves are not functioning[rosecityveincenter.com]

  • Thrombosis

    This condition is characterized by pooling of blood, chronic leg swelling, increased pressure, increased pigmentation or discoloration of the skin, and leg ulcers known as[my.clevelandclinic.org] Herein is presented a case of heterozygous Factor V Leiden (FVL) and hyperhomocysteinemia with homozygous methylenetetrahydrofolate reductase (MTHFR) mutations that caused[ncbi.nlm.nih.gov] V Leiden mutations.[ncbi.nlm.nih.gov]

  • Deep Vein Thrombosis

    CASE REPORT: A previously healthy 6-month-old male was brought to the emergency department by his family with a chief complaint of left leg swelling.[ncbi.nlm.nih.gov] Hematologic workup also discovered a factor V Leiden mutation, further predisposing the patient to DVT.[ncbi.nlm.nih.gov] V Leiden mutation.[ncbi.nlm.nih.gov]

  • May-Thurner Syndrome

    But providers should always rule out May-Thurner in a woman with unilateral swelling – typically in the left leg.[kansashealthsystem.com] V Leiden mutation on exogenous hormone therapy, with subsequent spontaneous rupture of the LCIV leading to fatal hemoperitoneum.[ncbi.nlm.nih.gov] Antiphospholipid antibodies (antiphosphatidylserine, anticardiolipin, and antiphosphatidyl-ethanolamine), factor V Leiden mutation by polymerase chain reaction, and homocyst[ncbi.nlm.nih.gov]

  • Lipedema

    In each group, the results were dismal as leg swelling worsened or was unchanged in greater than 90% whereas symptoms such as heaviness, fatigue, cramps (termed varicogenic[ncbi.nlm.nih.gov] Additional past history found in Table 1 ), polycystic ovarian syndrome or gluten allergy (6.3 0.2% each), costochondritis or narcolepsy (4.2 0.2% each), or a factor V Leiden[archivesofmedicine.com] Keywords: lipedema, leg swelling, lipodystrophy, localized adiposity, lower extremity liposuction This work is published and licensed by Dove Medical Press Limited.[dovepress.com]

  • Hereditary Deficiency of Antithrombin III

    Blood clots in the arms or legs usually cause swelling, redness, and pain.[medlineplus.gov] V leiden mutation and 2.0% for homocystenemia.[jpma.org.pk] Symptoms Patients will usually have symptoms of a blood clot, including: Coughing up blood Fainting Shortness of breath and pain when taking deep breaths Swelling of one leg[coordinatedhealth.com]

  • Liver Cirrhosis

    You may also get swelling in your legs, ankles or feet, known as peripheral oedema.[britishlivertrust.org.uk] The coincidence in a given patient of prothrombotic mutations, such as factor V Leiden or PAI-1 polymorphisms, can accelerate the fibrogenetic process.[ncbi.nlm.nih.gov] The recommended thrombophilia tests are: protein C activity; protein S activity; antithrombin activity; factor-V-Leiden gene (G1691A) mutation, APC ratio; prothrombin gene[dx.doi.org]

  • Nephrotic Syndrome

    We report the case of a 23-year-old woman with a 2-week history of swelling around the eyes and both legs, and generalized body swelling.[ncbi.nlm.nih.gov] Am J Hematol 72 : 234 –242, 2003 Price DT, Ridker PM: Factor V Leiden mutation and the risks for thromboembolic disease: A clinical perspective.[jasn.asnjournals.org] Protein loss causes low protein count in the blood (hypoalbuminemia) and edemas (excess fluid in the interstitial cavity which is between the cells, causes leg swelling most[medical-dictionary.thefreedictionary.com]

  • Venous Thrombosis

    Congenital causes of venous thrombosis have gained increasing prominence with the description of the factor V Leiden mutation and the prothrombin gene mutation.[ncbi.nlm.nih.gov] Deep vein thrombosis (DVT) can be a cause of long-term leg swelling and other symptoms, and it can be serious in the short-term.[ucdmc.ucdavis.edu] Abstract Congenital causes of venous thrombosis have gained increasing prominence with the description of the factor V Leiden mutation and the prothrombin gene mutation.[doi.org]

  • Hemophilia

    “Pseudo homozygous” activated protein C resistance due to double heterozygous factor V defects (factor V Leiden mutation and type I quantitative factor V defect) associated[doi.org]

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