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98 Possible Causes for Factor V Leiden Mutation, Petechiae, Purpura

  • Purpura Fulminans

    The clinical features of 15 heterozygous and 5 homozygous patients with factor V Leiden mutation were analyzed.[doi.org] Medscape: Purpura Fulminans[en.wikipedia.org] The patient's condition aggravated, with need for invasive mechanical ventilation and intermittent haemodialysis, and evolution from a petechiae-like rash to purpura and gangrene[ncbi.nlm.nih.gov]

  • Cutaneous Leukocytoclastic Vasculitis

    Protein C and protein S levels were normal and the factor V leiden mutation test was negative.[ispub.com] Patients with hyperglobulinemic purpura, which may be a subset of leukocytoclastic vasculitis, should be examined for associated conditions.[ncbi.nlm.nih.gov] Abstract A 71-year-old man presented with a high fever, polyarthralgia, petechiae and palpable purpura accompanied by livedoid change on his legs and feet.[ncbi.nlm.nih.gov]

  • Glanzmann Thrombasthenia

    Acquired Glanzmann's thrombasthenia (GT) is an uncommon accompaniment to immune thrombocytopenic purpura.[ncbi.nlm.nih.gov] . , Brandjes DP , Smits PH , van Mourik JA The role of platelets in venous thrombosis: a patient with Glanzmann's thrombasthenia and a factor V Leiden mutation suffering from[doi.org] Symptoms include purpura, petechiae, bruising, gingival bleeding, epistaxis, and menorrhagia.[ncbi.nlm.nih.gov]

  • Disseminated Intravascular Coagulation

    Effect of the factor V Leiden mutation on the incidence and outcome of severe infection and sepsis . Neth. J. Med. 70 , 306–310 (2012). 176. Hermans, P.[doi.org] Abstract Acute perturbations in the hemostatic balance of anticoagulation and procoagulation antecede the manifestation of purpura fulminans, a rare syndrome of intravascular[ncbi.nlm.nih.gov] Two weeks later, he was transferred to the West China Hospital with nasal hemorrhage for 1 week, hematochezia, hematuria, and petechiae for 5 days.[ncbi.nlm.nih.gov]

  • Hematologic Disease

    LS is a superior treatment for patients with idiopathic thrombocytopenic purpura and patients with small spleens.[ncbi.nlm.nih.gov] Examples include Factor V Leiden mutations, Protein C deficiency, and Lupus anticoagulant.[nhoh.com] The average platelet count in patients with petechiae was 48,000/mm 3 (range, 40,000-74,000/mm 3 ).[idoj.in]

  • Essential Thrombocythemia

    […] hypergammaglobulinemic purpura ( D89.0 ) cryoglobulinemic purpura ( D89.1 ) essential (hemorrhagic) thrombocythemia ( D47.3 ) hemorrhagic thrombocythemia ( D47.3 ) purpura[icd10data.com] Factor V Leiden mutation carriership and venous thromboembolism in polycythemia vera and essential thrombocythemia. Am J Hematol . 2002 Sep. 71(1):1-6. [Medline] .[emedicine.medscape.com] The remaining disorders consisted of polycythemia vera (2), smoker’s polycythemia (1), thrombotic thrombocytopenic purpura (1), familial protein C deficiency (1), IgA myeloma[stroke.ahajournals.org]

  • Pernicious Anemia

    No deficiencies in protein C and protein S were detected; they had normal antithrombin III function and factor V Leiden; no prothrombin gene mutations were detected.[ncbi.nlm.nih.gov] Abstract BACKGROUND: Thrombotic thrombocytopenic purpura (TTP) is a microangiopathic hemolytic anemia that requires emergent treatment with plasma exchange and is one of the[ncbi.nlm.nih.gov] Petechiae in the mammillary bodies. WKS, acute lesion. Periaqueductal lesions. WKS, acute lesion. Periaqueductal lesions. WKS, burned out lesion. WKS, burned out lesion.[neuropathology-web.org]

  • Chronic Kidney Insufficiency

    […] with renal failure may present as gastrointestinal bleeding, bleeding from cannulation sites, retinal haemorrhage, subdural haematoma, epistaxis, haematuria, ecchymosis, purpura[academic.oup.com] […] lack in antithrombin, protein C, protein S, factor V Leiden mutation, as well as polymorphisms in the TGF-β1 gene, NO synthase, PAI-1, angiotensin-converting enzyme, methylene[academic.oup.com] […] haemorrhage Subdural haematoma Epistaxis Haematuria Ecchymosis Purpura Bleeding from the gums Gingival bleeding Genital bleeding Haemoptysis Telangiectasia Haemarthrosis Petechiae[academic.oup.com]

  • Bleeding Diathesis

    KEYWORDS: GCS Glasgow Coma Scale; GOS-E Peds Pediatric Glasgow Outcome Scale–Extended; ICH intracerebral hematoma; ITP idiopathic thrombocytopenic purpura; PT prothrombin[ncbi.nlm.nih.gov] We tested for the presence of the Factor V Leiden mutation by PCR-amplifying a fragment of the factor V gene which contains the mutation site and then digesting the product[ncbi.nlm.nih.gov] An accurate description of the several forms of cutaneous bleeding (petechiae, purpuric spots, ecchymosis, haematomas, etc.) is needed for referrals and for controls.[ncbi.nlm.nih.gov]

  • Warfarin-induced Skin Necrosis

    RESULTS: There are several adverse skin manifestations associated with the use of oral anticoagulants, ranging from ecchymoses and purpura, haemorrhagic necrosis, maculopapular[ncbi.nlm.nih.gov] The laboratory screen demonstrated ATIII, antinuclear antibody, ANCA, absence of anticardiolipin antibodies, and C- and S-protein deficiency, one patients had factor V-Leiden[bloodjournal.org] Cutaneous findings include petechiae that progress to ecchymoses and hemorrhagic bullae.[ncbi.nlm.nih.gov]

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