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387 Possible Causes for Factor V Leiden Mutation, Purpura

  • HELLP Syndrome

    The toll-like receptor-4 (TLR-4) and factor V Leiden mutation participate both in development of preeclampsia and the HELLP syndrome.[ncbi.nlm.nih.gov] Thrombotic thrombocytopenic purpura can mimic HELLP syndrome late in gestation.[ncbi.nlm.nih.gov] […] before diagnosis of HELLP syndrome; chronic use of corticosteroids; chronic diseases that alter laboratory parameters of HELLP Syndrome, such as chronic liver disease or purpura[ncbi.nlm.nih.gov]

  • Essential Thrombocythemia

    Factor V Leiden mutation carriership and venous thromboembolism in polycythemia vera and essential thrombocythemia. Am J Hematol . 2002 Sep. 71(1):1-6. [Medline] .[emedicine.medscape.com] […] hypergammaglobulinemic purpura ( D89.0 ) cryoglobulinemic purpura ( D89.1 ) essential (hemorrhagic) thrombocythemia ( D47.3 ) hemorrhagic thrombocythemia ( D47.3 ) purpura[icd10data.com] The platelet count may also transiently rise above normal limits with effective treatment for immune thrombocytopenic purpura.36 Following splenectomy for any condition, the[medtextfree.wordpress.com]

  • Purpura Fulminans

    .— Two adults with purpura fulminans related to sepsis were found to be heterozygous for the Factor V Leiden mutation.[jamanetwork.com] […] fulminans lesions look similar to traumatic skin bleeds or purpuric rashes, such as immune thrombocytopenic purpura or thrombotic thrombocytopenic purpura; however, purpura[en.wikipedia.org] Antigen levels may be contributory if interfering factors (e.g. factor V Leiden mutation, antiphospholipid antibodies, direct thrombin inhibitors) are present.[flipper.diff.org]

  • Neonatal Purpura Fulminans

    Purpura fulminans is an acute and frequently fatal disorder characterized by sudden onset of progressive cutaneous hemorrhage and necrosis due to dermal vascular thrombosis[ncbi.nlm.nih.gov] . , 1998: Homozygous Factor V Leiden mutation in a child with meningococcal purpura fulminans .[eurekamag.com] Neonatal purpura fulminans is rare and may be inherited or acquired. It may ultimately lead to multiorgan failure and death.[ncbi.nlm.nih.gov]

  • Hypofibrinogenemia

    This is the first report of purpura and hypofibrinogenemia induced by allopurinol and the pathophysiology underlying this reaction remained unknown.[ncbi.nlm.nih.gov] V Leiden mutation.[ncbi.nlm.nih.gov] Code Applicable To Afibrinogenemia, acquired Consumption coagulopathy Diffuse or disseminated intravascular coagulation [DIC] Fibrinolytic hemorrhage, acquired Fibrinolytic purpura[icd10data.com]

  • Pernicious Anemia

    No deficiencies in protein C and protein S were detected; they had normal antithrombin III function and factor V Leiden; no prothrombin gene mutations were detected.[ncbi.nlm.nih.gov] Thrombotic thrombocytopenic purpura (TTP) is a microangiopathic hemolytic anemia that requires emergent treatment with plasma exchange and is one of the most important conditions[ncbi.nlm.nih.gov] Purpurae may be present due to thrombocytopenia. The following investigations are helpful in establishing the diagnosis of pernicious anemia.[symptoma.com]

  • Cutaneous Leukocytoclastic Vasculitis

    Protein C and protein S levels were normal and the factor V leiden mutation test was negative.[ispub.com] Patients with hyperglobulinemic purpura, which may be a subset of leukocytoclastic vasculitis, should be examined for associated conditions.[ncbi.nlm.nih.gov] The absence of IgA ACAs in Henoch-Schönlein purpura argues against their being an epiphenomenon in vasculitis.[ncbi.nlm.nih.gov]

  • Coagulation Abnormalities

    We determined levels of protein C, protein S, factor VIII, and fibrinogen and tested for the factor V Leiden and prothrombin G20210A mutations.[ncbi.nlm.nih.gov] […] and other hemorrhagic conditions D69.0 Allergic purpura D69.1 Qualitative platelet defects D69.2 Other nonthrombocytopenic purpura D69.3 Immune thrombocytopenic purpura D69.4[icd10data.com] The prevalence of factor V Leiden mutation and G20210A prothrombin gene variant was similar in the MM patients and in the control group.[haematologica.org]

  • Congenital Afibrinogenemia

    Pathogenesis and Treatment of BiomaterialAssociated Overview of Complex Thrombohemorrhagic Disorders Consumptive Thrombohemorrhagic Disorders The Thrombotic Thrombocytopenic Purpura[books.google.com] In case of thrombosis, differential diagnosis also includes congenital or acquired thrombophilia (antithrombin deficiency, protein C or S deficiency, Factor V Leiden mutation[orpha.net] Current treatment procedures Infantile hemangiomas are the most common benign tumors Thrombotic microangiopathies – hemolytic-uremic syndromes and thrombotic thrombocytopenic purpura[prolekare.cz]

  • Hemophilia A

    Although the efficacy of Factor V Leiden was at issue, when it was applied in FII G20210A mutation, the thrombosis formation tendency increased [ 15 ].[casesjournal.biomedcentral.com] Soft tissue bruising (purpura) over trunk or extremities in an otherwise healthy person (particularly male), without accompanying systemic signs such as fever should prompt[cancertherapyadvisor.com] Arbini AA, Mannucci PM, Bauer KA (1995) Low prevalence of the factor V Leiden mutation among "severe" hemophiliacs with a "milder" bleeding diathesis.[omicsonline.org]

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