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3,706 Possible Causes for Failure to Thrive, Flat Supraorbital Ridges, Wide Space Between the First and Second Toe

  • Dubowitz Syndrome

    Facial appearance is characteristic with narrow or triangular shaped head and high or sloping forehead, flat supraorbital ridge, scanty lateral eyebrows, short palpebral fissures[orpha.net] Failure to Thrive : growth failure, or failure to thrive (FTT), is a descriptive term and not a specific diagnosis.[ric.edu] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Gorlin-Chaudhry-Moss Syndrome

    […] to thrive And another 116 symptoms.[mendelian.co] […] to thrive Pediatric failure to thrive disease Disease or Syndrome 542 0.100 0 CUI: C2227134 Disease: mandibular excess (physical finding) mandibular excess (physical finding[disgenet.org] […] to thrive ; Feeding difficulties ; Gastroesophageal reflux ; Generalized hypotonia ; Heterotopia ; High, narrow palate ; Hydrocephalus ; Hypermetropia ; Hypertelorism ; Hypertrichosis[mousephenotype.org]

    Missing: Wide Space Between the First and Second Toe
  • Down Syndrome

    Symptoms included constipation (20%), gastroesophageal reflux (18%), failure to thrive (10%), diarrhea (6%), and extreme short stature (4%).[journals.lww.com] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org]

    Missing: Flat Supraorbital Ridges
  • Weaver Syndrome

    Physical findings included prominent supraorbital ridges, downslanting palpebral fissures, a broad nose with full nasal tip, pointed chin, tall slender build, and flat feet[karger.com] Pediatr Radiol 5:53–57 Google Scholar Marshall RE, Graham CB, Scott CR, Smith DW (1971) Syndrome of accelerated skeletal maturation and relative failure of thrive: A newly[link.springer.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Syndromic Diarrhea

    Unexplained diarrhoea and failure to thrive in 2 siblings with unusual facies and abnormal scalp hair shafts: a new syndrome.[doi.org] […] to thrive.[ojrd.com] Severe malabsorption leads to early and severe protein energy malnutrition with failure to thrive and patients require parenteral nutrition (PN).[ojrd.com]

    Missing: Wide Space Between the First and Second Toe
  • Neonatal Adrenoleukodystrophy

    The clinical findings of the ZS are dysmorphic features (prominent forehead, hypertelorism, epicanthal folds, flat supraorbital ridges, broad nasal bridge, large fontanelles[neuropathology-web.org] Abnormal clinical features in neonatal adrenoleukodystrophy are generally present at birth, and include muscle hypotonia, severe psychomotor retardation, and failure to thrive[ncbi.nlm.nih.gov] […] to thrive and severely delayed psychomotor development.[orpha.net]

    Missing: Wide Space Between the First and Second Toe
  • Russell-Silver Syndrome

    Russell-Silver syndrome is characterized by asymmetric intrauterine growth retardation, postnatal failure to thrive, distinct facial features, limb asymmetry, excessive sweating[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Mosaic trisomy 7 was diagnosed after birth, on fibroblasts karyotype performed for blaschkolinear pigmentary skin anomalies and failure to thrive.[ncbi.nlm.nih.gov]

    Missing: Flat Supraorbital Ridges
  • Ring Chromosome 10

    They showed a phenotype consistent with the “ring syndrome” with failure to thrive, minor dysmporphic features and no major anomalies.[tp.amegroups.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] It had feeding difficulties and failed to thrive and had a respiratory arrest at 4 months.[tp.amegroups.com]

    Missing: Flat Supraorbital Ridges
  • Pseudoaminopterin Syndrome

    […] holoprosencephaly Severe X-linked intellectual disability, Gustavson type Severe achondroplasia-developmental delay-acanthosis nigricans syndrome Severe feeding difficulties-failure[se-atlas.de] Chandran syndrome Metaphyseal undermodeling, spondylar dysplasia, and overgrowth Macrocephaly-capillary malformation Warman Mulliken Hayward syndrome Cataract-microcephaly-failure[checkrare.com] […] to thrive-microcephaly due to ASXL3 deficiency syndrome Severe intellectual disability and progressive spastic paraplegia Severe intellectual disability-epilepsy-anal anomalies-distal[se-atlas.de]

    Missing: Wide Space Between the First and Second Toe
  • Zellweger Syndrome

    The clinical findings of the ZS are dysmorphic features (prominent forehead, hypertelorism, epicanthal folds, flat supraorbital ridges, broad nasal bridge, large fontanelles[neuropathology-web.org] A 7-month-old infant with failure to thrive and malnutrition developed a corneal ulcer. Fortified antibiotic eye drops were administered without improvement.[ncbi.nlm.nih.gov] It is characterized by severe hypotonia, failure to thrive, psychomotor retardation, liver dysfunction, and sensorineural hearing impairment.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe

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