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12 Possible Causes for Failure to Thrive, Nausea, Wide Space Between the First and Second Toe

  • Down Syndrome

    Symptoms included constipation (20%), gastroesophageal reflux (18%), failure to thrive (10%), diarrhea (6%), and extreme short stature (4%).[journals.lww.com] A 35-year-old female patient had visited another hospital for 1 month for abdominal discomfort, nausea, constipation, and palpable mass.[ncbi.nlm.nih.gov] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org]

  • Multiple Endocrine Neoplasia Type 2B

    Feeding difficulties--poor suck to the point of failure to thrive--were present in the neonatal periods of seven of our nine patients who had MEN 2b.[ncbi.nlm.nih.gov] […] sweating Racing heartbeat (tachycardia) and palpitations (skipped heartbeats) Feelings of anxiety or feelings of extreme fright Pain in the lower chest or upper abdomen Nausea[stjude.org] Figure 3 The first toe is longer than the others and there is a wide space between the first and second toe.[ijponline.biomedcentral.com]

  • Dubowitz Syndrome

    Failure to Thrive : growth failure, or failure to thrive (FTT), is a descriptive term and not a specific diagnosis.[ric.edu] Likewise, the diarrhea and nausea can be treated with over-the-counter medications, and the hyperactivity may be treated with prescription drugs, in some cases.[wisegeek.net] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Russell-Silver Syndrome

    Russell-Silver syndrome is characterized by asymmetric intrauterine growth retardation, postnatal failure to thrive, distinct facial features, limb asymmetry, excessive sweating[ncbi.nlm.nih.gov] These infrequent/rare side effects include the following: mild transient hypoglycemia; injection site reactions such as rashes; transient headaches, nausea and/or vomiting[magicfoundation.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Cutis Laxa

    […] to thrive, developmental delay, dysmorphism, osseous abnormality, and CNS manifestations.[ncbi.nlm.nih.gov] CASE PRESENTATION A 50-year-old female with history of CL diagnosed in 1991, presented to emergency room with complaints of nausea, vomiting and abdominal distension.[academic.oup.com] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br]

  • Weaver Syndrome

    Pediatr Radiol 5:53–57 Google Scholar Marshall RE, Graham CB, Scott CR, Smith DW (1971) Syndrome of accelerated skeletal maturation and relative failure of thrive: A newly[link.springer.com] Any-grade AEs reported in more than 5% of patients included nausea (20%), thrombocytopenia (19%), cough (14%), diarrhea (11%), fatigue (12%), and asthenia (10%).[targetedonc.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Short Stature due to Endocrine Disorder

    […] to thrive Faltering weight Weight faltering [ more ] 0001508 Insulin resistance Body fails to respond to insulin 0000855 Intellectual disability, mild Mental retardation,[rarediseases.info.nih.gov] All patients were able to tolerate the maximum dosage of liraglutide (1.8 mg once daily), except one patient who continued with a dose of 1.2 mg/day because of persistent nausea[doi.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Familial Congenital Nasolacrimal Duct Obstruction

    Large shunts may have apical diastolic murmur, difficulty feeding and failure to thrive.[aimted.com] […] bleeding (1) Hepatitis (4) Hepatitis A (2) Hepatitis B (2) Hepatitis C (7) Hepatotoxicity (1) Intestinal obstruction (1) Irritable bowel syndrome (1) Lactose intolerance (1) Nausea[innovations.ahrq.gov] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

  • Mild Dysmorphic Features

    Diseases related with Failure to thrive and Eczema In the following list you will find some of the most common rare diseases related to Failure to thrive and Eczema that can[mendelian.co] […] reassurance Social withdrawal and increased time spent alone Symptoms of social phobia, or social anxiety, including severe blushing, sweating, shuddering, shyness, trembling or nausea[draxe.com] , fourth, and fifth fingers; feet held in eversion, prominent heels; wide space between the first and second toes; proximally placed fifth toes; hypotonia; increased skin[ssmc-tl.com]

  • MORM Syndrome

    […] to thrive in infancy Faltering weight in infancy Weight faltering in infancy [ more ] 0001531 Feeding difficulties in infancy 0008872 Finger syndactyly 0006101 Genu valgum[rarediseases.info.nih.gov] Pregnant women developing HELLP syndrome have reported experiencing one or more of these symptoms: Headache Nausea/vomiting/indigestion with pain after eating Abdominal or[preeclampsia.org] Slow weight gain, especially during the first several years of life, is also a common problem and many children are diagnosed as "failure to thrive".[williams-syndrome.org]

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