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293 Possible Causes for Failure to Thrive, Onset at Age 5-10 Years

  • Hypertension

    In general, all patients with young onset-age (  40-50 years) or resistant hypertension should be screened for secondary forms.[] Relevant information includes the following: Prematurity Bronchopulmonary dysplasia History of umbilical artery catheterization Failure to thrive History of head or abdominal[] Failure to thrive, seizures, irritability, lack of energy, and difficulty in breathing can be associated with hypertension in newborns and young infants.[]

  • Bartter's Disease

    Clinical findings Proximal muscle weakness, failure to thrive, short stature, convulsions, tetany, cramps, ileus, gout, mental retardation, enuresis, nocturia, polyuria, salt[] Bartter's syndrome patients usually present aged 5 years with signs of vascular volume depletion, polyuria, and polydipsia.[] Presentation is often in childhood with gastrointestinal upset, failure to thrive and polyuria.[]

  • Cystinosis

    Cystinosis is the major cause of inherited Fanconi syndrome, and should be suspected in young children with a failure to thrive and with signs of renal proximal tubular damage[] years.[] The history of muscle weakness, failure to thrive, polydipsia, and polyuria prompted subsequent clinical and laboratory evaluations, leading to the correct diagnosis of cystinosis[]

  • Peeling Skin Syndrome Type A

    Patients are usually in good general health but may present with mild failure to thrive.[] It is characterized by sparse, kinky hair; failure to thrive; and progressive deterioration of the nervous system.[] Affected patients may present with failure to thrive and recurrent secondary infections (especially with Staphylococcus aureus).[]

  • Congenital Sucrase-Isomaltase Deficiency

    […] of symptoms before 1 year of age, 7 between 1 and 10 years old, and 5 after 10 years of age (22) ; however, the age at which a diagnosis was made was shifted to the right[] Case Presentation The patient was a 10 month old caucasian female infant presenting with failure to thrive (FTT), metabolic acidosis, and hypercalcemia.[] These digestive problems can lead to failure to gain weight and grow at the expected rate (failure to thrive) and malnutrition.[]

  • Juvenile Cystinosis

    years.[] Failure to thrive is generally noticed after approximately age six months; signs of renal tubular Fanconi syndrome (polyuria, polydipsia, dehydration, and acidosis) appear[] The disease results in deposition of crystals throughout the body; if untreated, it leads to failure to thrive, profound metabolic imbalance, early end-stage renal disease[]

  • Neonatal Adrenoleukodystrophy

    Abnormal clinical features in neonatal adrenoleukodystrophy are generally present at birth, and include muscle hypotonia, severe psychomotor retardation, and failure to thrive[] Childhood cerebral type is the most common type and age of onset is generally between 4 to 10 years of age, progressing rapidly to vegetative state and death within 2 years[] […] to thrive and severely delayed psychomotor development.[]

  • Sucrose Intolerance

    […] of symptoms before 1 year of age, 7 between 1 and 10 years old, and 5 after 10 years of age (22) ; however, the age at which a diagnosis was made was shifted to the right[] Diarrhea is often described as "fermentative" due to the abundance of carbohydrates, whereas additional findings include failure to thrive, bloating, and abdominal distension[] Symptoms of sucrose intolerance (GSID) in infants and children are chronic abdominal pain, watery diarrhea, failure to thrive (poor physical growth), abdominal swelling, gassiness[]

  • Cockayne Syndrome

    […] extremely significant ( P 1.36   10 6 ); at 5 years, survival is 60% for those patients with early cataracts and 95% for those without ( Figure 4a ).[] Of these, failure to thrive, photosensitivity, and intellectual disability (language delays) developed before 2 or 3 years of age, whereas deafness, sunken eyes, and basal[] CAMFAK syndrome is an inherited disease characterized by congenital cataracts, microcephaly, failure to thrive, and kyphoscoliosis with onset in early infancy.[]

  • Pancreatoblastoma

    Clinical description Pancreatoblastoma most often present in children under the age of 10 (mean of 5 years). Onset in adulthood (third/ fourth decade) is extremely rare.[] Symptoms are often non-specific and include a large abdominal mass, abdominal distension/pain, failure to thrive, diarrhea, vomiting, and jaundice.[] […] to thrive, and is characterized histologically by multiple lines of differentiation (acinar, ductal, mesenchymal, neuroendocrine) and the presence of squamoid nests.[]

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