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3,737 Possible Causes for Failure to Thrive, Preaxial Polysyndactyly, Wide Space Between the First and Second Toe

  • Kleiner Holmes Syndrome

    His younger brother had preaxial polysyndactyly of the great toes.[omim.org] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first[rarediseases.info.nih.gov]

    Missing: Failure to Thrive
  • Dubowitz Syndrome

    Failure to Thrive : growth failure, or failure to thrive (FTT), is a descriptive term and not a specific diagnosis.[ric.edu] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Afterwards, the child is sometimes labeled as failure to thrive . The head is usually microcephalic and face is small with some elongation with age.[dubowitzsyndrome.net]

    Missing: Preaxial Polysyndactyly
  • Down Syndrome

    Symptoms included constipation (20%), gastroesophageal reflux (18%), failure to thrive (10%), diarrhea (6%), and extreme short stature (4%).[journals.lww.com] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org]

    Missing: Preaxial Polysyndactyly
  • Atelosteogenesis Type 2

    Feet with preaxial polysyndactyly and clubfoot. Sprengel anomaly. Cardiac and genitourinary anomalies.[musculoskeletalkey.com] In addition to the respiratory difficulties, feeding difficulties can result in a failure to thrive. The severity of airway compromise dictates management.[oralmaxillo-facialsurgery.blogspot.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Marshall-Smith Syndrome

    It is hoped that the etiology of the syndrome will be discovered as more cases are recognized and reported by pediatricians caring for infants with failure to thrive, advanced[ncbi.nlm.nih.gov] It is characterized by usually postaxial polydactyly of the hands, preaxial polysyndactyly of the feet, macrocephaly, and hypertelorism.[whonamedit.com] Marshall A syndrome of motor and mental retardation, accelerated skeletal maturation, failure to thrive, and abnormal facies.[whonamedit.com]

    Missing: Wide Space Between the First and Second Toe
  • Russell-Silver Syndrome

    Russell-Silver syndrome is characterized by asymmetric intrauterine growth retardation, postnatal failure to thrive, distinct facial features, limb asymmetry, excessive sweating[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Mosaic trisomy 7 was diagnosed after birth, on fibroblasts karyotype performed for blaschkolinear pigmentary skin anomalies and failure to thrive.[ncbi.nlm.nih.gov]

    Missing: Preaxial Polysyndactyly
  • Ring Chromosome 10

    They showed a phenotype consistent with the “ring syndrome” with failure to thrive, minor dysmporphic features and no major anomalies.[tp.amegroups.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] It had feeding difficulties and failed to thrive and had a respiratory arrest at 4 months.[tp.amegroups.com]

    Missing: Preaxial Polysyndactyly
  • Familial Congenital Nasolacrimal Duct Obstruction

    polysyndactyly of the feet, soft tissue syndactyly of the hands, and brachydactyly and duplication of the second toe may be seen in many of these patients.[entokey.com] Large shunts may have apical diastolic murmur, difficulty feeding and failure to thrive.[aimted.com] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

  • Acrocallosal Syndrome

    The patient underwent surgery for preaxial polysyndactyly of both hands and feet. The similarity to the Greig syndrome is discussed.[ncbi.nlm.nih.gov] A seven year old female with severe developmental delays, failure to thrive and growth retardation, infantile spasms, a cardiac vascular ring and right-sided aortic arch,[ncbi.nlm.nih.gov] Fig. 3 Figure 4: Radiograph of both foot showing preaxial polysyndactyly.[jemds.com]

    Missing: Wide Space Between the First and Second Toe
  • Esophagitis

    It presents with failure to thrive, nausea, and vomiting in children and is a common reason for dysphagia and food impaction in adults.[ncbi.nlm.nih.gov] Dysphagia Chest or upper abdominal pain Food stuck in the esophagus Heartburn that doesn’t respond to medication Regurgitation In children: vomiting, poor weight gain or failure[nm.org] In infants, this disease may be associated with failure to thrive. In some situations, avoiding certain food allergens will be an effective treatment for EoE.[aarda.org]

    Missing: Preaxial Polysyndactyly Wide Space Between the First and Second Toe

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