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48 Possible Causes for Failure to Thrive, Risk of Cancer Possibly Increased, Tyrosine Increased

  • Tyrosinemia Type 1

    The patient's newborn screening test revealed increased concentrations of methionine and tyrosine.[ncbi.nlm.nih.gov] The medication lessens the risk for liver cancer. Your child should start taking Nitisinone as soon as possible.[newbornscreening.info] Although failure to thrive is one of the typical features in HT1, our proband, similar to the reported Scandinavian patients, had normal growth and development.[ncbi.nlm.nih.gov]

  • Tyrosinemia

    Serum tyrosine increases due to tyrosine aminotransferase deficiency resulting in the deposition of tyrosine crystals in the cornea and in corneal inflammation.[ncbi.nlm.nih.gov] The medication lessens the risk for liver cancer. Your child should start taking Nitisinone as soon as possible.[newbornscreening.info] Similarities include failure to thrive with hypoproteinemia, micronodular cirrhosis, alpha-fetoprotein positive hepatocellular carcinoma, renal Fanconi syndrome with renal[ncbi.nlm.nih.gov]

  • Transient Neonatal Hypertyrosinemia

    There are increased concentrations of tyrosine in blood and urine.[wvdhhr.org] The medication lessens the risk for liver cancer. Your child should start taking Nitisinone as soon as possible.[newbornscreening.info] Gastrointestinal Involvement, Failure to Thrive, Anemia, and Recurrent Infections Gastrointestinal (GI) findings (anorexia, failure to thrive, chronic vomiting) and osteoporosis[obgynkey.com]

  • Hypothyroidism

    3 deiodinase due to therapy with tyrosine kinase inhibitors [4].[flexikon.doccheck.com] There is an association between chronic thyroiditis and thyroid nodules, but whether this association is related to an increased risk of thyroid cancer is controversial. 7[racgp.org.au] Infants and children may present more often with lethargy and failure to thrive. Women who have hypothyroidism may present with menstrual irregularities and infertility.[web.archive.org]

  • Zinc Deficiency

    A 1994 trial showed that zinc doubled the rate of body mass increase in the treatment of anorexia nervosa.[en.wikipedia.org] Esophageal cancer. Early research has linked low intake of zinc with an increased risk of esophageal cancer.[webmd.com] Links: acrodermatitis enteropathica diarrhoea alopecia failure to thrive taste disturbance[gpnotebook.co.uk]

  • Sarcosinemia

    This sensitive technology allows for measurement of both phenylalanine and tyrosine, showing elevated phenylalanine levels in conjunction with an increased phenylalanine to[genico.ch] Whether dietary or supplemental choline is beneficial or harmful to humans is undefined, possible dangers include increased risk of cardiovascular disease and cancer, while[wikivisually.com] Clinical manifestations include poor feeding in an infant with failure to thrive and developmental delays; however, no consistent clinical syndrome has been reported.[medical-dictionary.thefreedictionary.com]

  • Urethral Stricture

    Other abnormalities include elevated α -fetoprotein (especially in acutely ill infants), increased plasma levels of tyrosine, phenylalanine and methionine, increased urinary[orpha.net] The medication lessens the risk for liver cancer. Your child should start taking Nitisinone as soon as possible.[newbornscreening.info] Signs and SymptomsOpen While most babies with Tyrosinemia appear normal at birth, early signs of the disease can include: poor weight gain (failure to thrive) feeding problems[newbornscreening.on.ca]

  • Gaucher Disease

    While STAT1 expression was not influenced by the Gaucher phenotype or IFNγ stimulation, the IFNγ-induced increase in the tyrosine phosphorylation of STAT1 was significantly[doi.org] As enzyme replacement and substrate reduction therapies are expensive and still associated with inflammation, increased risk of cancer and Parkinson disease, targeting C5aR1[ncbi.nlm.nih.gov] The various symptoms and the age when they are most likely to present are as follows: [4] Newborn Congenital ichthyosis Organomegaly Failure to thrive Brain stem dysfunction[emedicine.medscape.com]

  • Urinary Retention

    Other abnormalities include elevated α -fetoprotein (especially in acutely ill infants), increased plasma levels of tyrosine, phenylalanine and methionine, increased urinary[orpha.net] increases the risk of impairments in urinary and renal function [ 17 ].[karger.com] Signs and SymptomsOpen While most babies with Tyrosinemia appear normal at birth, early signs of the disease can include: poor weight gain (failure to thrive) feeding problems[newbornscreening.on.ca]

  • Hypervitaminosis D

    In EGFR-driven cancers, prevention of increases in LIP partially accounts for the potent antiproliferative properties of EGFR-tyrosine kinase inhibitors ( 12 ).[ajprenal.physiology.org] Our study is limited by the use of a preneoplastic lesion, which confers a significantly increased risk of ESCC ( 12 ) but is not itself cancer.[doi.org] We present a 5-month-old infant who had failure to thrive, refusal to feed, delayed motor development, truncal hypotonia, and dehydration.[ncbi.nlm.nih.gov]

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