Failure to Thrive in Infancy: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Failure to Thrive in Infancy

Noonan Syndrome

[…] to thrive in infancy Faltering weight in infancy Weight faltering in infancy [ more ] 0001531 High, narrow palate Narrow, high-arched roof of mouth Narrow, highly arched [rarediseases.info.nih.gov]

Behavioral characteristics include failure to thrive in infancy (40%), motor developmental delay (20%), learning disability (15%), language delay (20%), mild hearing loss [indianpediatrics.net]

[…] bite Malalignment of upper and lower dental arches Misalignment of upper and lower dental arches [ more ] 0000689 Epicanthus Eye folds Prominent eye folds [ more ] 0000286 Failure [rarediseases.info.nih.gov]

Nephropathic Cystinosis

[…] to thrive in infancy Faltering weight in infancy Weight faltering in infancy [ more ] 0001531 Frontal bossing 0002007 Generalized aminoaciduria 0002909 Genu valgum Knock [rarediseases.info.nih.gov]

[…] cystine 0003358 Episodic metabolic acidosis 0004911 Exocrine pancreatic insufficiency Inability to properly digest food due to lack of pancreatic digestive enzymes 0001738 Failure [rarediseases.info.nih.gov]

Freeman-Sheldon Syndrome

But swallowing difficulties as well as vomiting can lead to failure to thrive during infancy and in some cases retarded growth can occur. [syndrome.org]

Other issues, particularly in infancy include feeding difficulties related to swallowing, frequent vomiting and a failure to thrive. * This composite image of Arthrogryposis [fdna.health]

Infancy may be characterised by failure-to-thrive for many patients with FBS due to associated dysphagia, microstomia, micrognathia, high palate, and microglossia. [ojrd.biomedcentral.com]

18-Hydroxylase Deficiency

[…] to thrive in infancy Hyperkalemia Decreased circulating aldosterone level Increased level of 3-hydroxy-3-methylglutaric acid in urine Need help with a diagnosis? [mendelian.co]

[…] to thrive ; Feeding difficulties in infancy ; Growth delay ; Hyperkalemia ; Hyponatremia ; Hypotension ; Increased circulating renin level ; Neonatal onset ; Renal salt wasting [mousephenotype.org]

Top 5 symptoms associated to CYP11B2 gene Symptoms // Phenotype % Cases Autosomal recessive inheritance Common - Between 50% and 80% cases Failure to thrive in infancy Common [mendelian.co]

Abetalipoproteinemia

It results in fatty stools, diarrhea, failure to thrive in infancy, and problems with nerves. [web.archive.org]

Symptoms Failure to thrive (grow) in infancy Fatty stools that appear pale in color Frothy stools Abnormally foul-smelling stools Protruding abdomen Developmental delay Poor [medical-dictionary-search-engines.com]

Symptoms include: Balance and coordination difficulties Curvature of spine Decreased vision that gets worse over time Developmental delay Failure to thrive (grow) in infancy [nlm.nih.gov]

Component Complement 5 Deficiency

[…] erythroderma, diarrhea, and failure to thrive Erythroderma desquamativa of Leiner Erythroderma Desquamativum of Infancy Leiner disease Leiner-Moussous Desquamative Erythroderma [wikidata.org]

Synonyms Generalized erythroderma, diarrhea, and failure to thrive Erythroderma Desquamativum of Infancy Leiner-Moussous Desquamative Erythroderma Overview No overview is [rarediseases.org]

[…] also known as generalized erythroderma, diarrhea, and failure to thrive. [malacards.org]

Hawkinsinuria

It results in metabolic acidosis and failure to thrive in infancy. Hypertyrosinemia is minimal or absent. [ommbid.mhmedical.com]

Metabolic acidosis and failure to thrive appear to be confined to infancy. [ncbi.nlm.nih.gov]

[…] to thrive in infancy Nephrolithiasis Abdominal distention Malabsorption Abnormality of metabolism/homeostasis Nevus Weight loss Fatigue Hypoglycemia Diffuse cerebellar atrophy [mendelian.co]

Postaxial Oligodactyly, Tetramelic

Allergies - environmental, food, medication: NKDA Clinical symptoms and physical findings Growth parameters Weight for age Decreased body weight ( Failure to thrive Failure [playground.phenotips.org]

[…] to thrive in infancy Eunuchoid habitus Musculoskeletal Postaxial foot polydactyly Click on terms below (extracted from the phenotypic description) to disable or re-enable [playground.phenotips.org]

Ventricular Septal Defect

[…] to thrive in infancy) Heart failure Infective endocarditis (bacterial infection of the heart) Pulmonary hypertension (high blood pressure in the lungs) leading to failure [nlm.nih.gov]

[…] ventricle from the aorta) Damage to the electrical conduction system of the heart during surgery (causing an irregular or slow heart rhythm) Delayed growth and development (failure [medlineplus.gov]

[…] left ventricle from the aorta) Damage to the electrical conduction system of the heart during surgery (causing an irregular heart rhythm) Delayed growth and development ( failure [ufhealth.org]

Disproportionate Short Stature - Ptosis - Valvular Heart Lesions

[…] to thrive in infancy as a result of severe postnatal feeding difficulties; short stature; developmental delay or intellectual disability; coarse facial features (full lips [rasopathiesnet.org]

Infants with Williams syndrome are often born small for their family and 70% are diagnosed with failure to thrive during infancy. [encyclopedia.com]

Gastrointestinal tract [ edit ] Failure to thrive from infancy to puberty (75%) Decreased appetite Digestive problems Frequent or forceful vomiting Swallowing difficulties [en.wikipedia.org]

Transient Neonatal Hypertyrosinemia

It results in metabolic acidosis and failure to thrive in infancy. Hypertyrosinemia is minimal or absent. [ommbid.mhmedical.com]

Diagnostic Approach to Inborn Errors of Metabolism with Chronic Diarrhea, Poor Feeding, Vomiting, Failure to Thrive Early Infancy Disorders Associated with Extraneurological [obgynkey.com]

Severe metabolic acidosis, ketosis, failure to thrive, mild hepatomegaly, and an unusual odor (like that of a swimming pool) are described. [clinicalgate.com]

Prader-Willi Syndrome

[…] to thrive during infancy; followed by hyperphagia and excessive weight gain later in childhood. [mdpi.com]

[…] to thrive in infancy weak cry aggressive behavior abnormal facial features almond-shaped eyes small, down-turned mouth Physical exam small for gestational age hypoplastic [orthobullets.com]

Feeding concerns, including the failure to thrive in infancy and obesity in later childhood, need close supervision by a dietitian. [nationwidechildrens.org]

Noonan Syndrome 3

Gastrointestinal tract [ edit ] Failure to thrive from infancy to puberty (75%) Decreased appetite Digestive problems Frequent or forceful vomiting Swallowing difficulties [en.wikipedia.org]

Chromosome 16q22 Deletion Syndrome

OMIM : 57 The interstitial 16q22 deletion syndrome is a multiple congenital anomaly disorder associated with failure to thrive in infancy, poor growth, delayed psychomotor [malacards.org]

The interstitial 16q22 deletion syndrome is a multiple congenital anomaly disorder associated with failure to thrive in infancy, poor growth, delayed psychomotor development [ncbi.nlm.nih.gov]

PAFAH1B1-Associated Lissencephaly and Subcortical Band Heterotopia

Other related symptoms, usually present at birth and in infancy, include issues with feeding, failure to thrive, low muscle tone in early infancy followed by an increased [fdna.health]

Monogenic Diabetes

Affected individuals have slow growth before birth followed by hyperglycemia, dehydration and failure to thrive in infancy. [rarediseases.info.nih.gov]

X-linked Mental Retardation Type Cabezas

The child displayed feeding difficulty and failure to thrive in newborn infancy. [ncbi.nlm.nih.gov]

Cardio-Facio-Cutaneous Syndrome Type 4

Failure to thrive during infancy is typical, as are gastrointestinal complications such as reflux, vomiting, oral aversion, and constipation. [invitae.com]

Mitochondrial Complex 3 Deficiency Nuclear Type 4

[…] to thrive Faltering weight Weight faltering [ more ] 0001508 Feeding difficulties in infancy 0008872 Generalized hypotonia Decreased muscle tone Low muscle tone [ more ] [rarediseases.info.nih.gov]

[…] transaminase High liver enzymes 0002910 Emotional lability Emotional instability 0000712 Exercise intolerance Decreased ability to exercise Inability to exercise [ more ] 0003546 Failure [rarediseases.info.nih.gov]

Mosaic Trisomy 7

Mosaic trisomy 9 is commonly characterized by growth deficiency beginning before birth, failure to grow and gain weight at the expected rate (failure to thrive) during infancy [rarediseases.org]

Mitochondrial Complex 3 Deficiency Nuclear Type 6

Neonatal Diabetes Mellitus

Affected individuals have slow growth before birth followed by hyperglycemia, dehydration and failure to thrive in infancy. [resourcerepository.org]

Bartter Syndrome Type 5

[…] to thrive in infancy, EAST syndrome Classic Bartter III (602522) CLCNKB/1p36 ClC-Kb chloride channel DCT Thiazide type Hypomagnesemia, hypocalciuria, EAST syndrome Bartter [hindawi.com]

Beginning in infancy, affected individuals often fail to grow and gain weight at the expected rate (failure to thrive). [medlineplus.gov]

Antenatal presentation associates polyhydramnios, premature birth, postnatal polyuria complicated by severe dehydration episodes, recurrent vomiting, failure to thrive, growth [nature.com]

Orotic Aciduria Type 2

[…] to thrive in infancy Poor suck Deep philtrum Bicuspid aortic valve Torticollis Vasculitis Bilateral single transverse palmar creases Aortic valve stenosis Hyperpigmentation [mendelian.co]

Babinski sign Pes cavus Prominent nose Lymphedema Decreased muscle mass Proximal placement of thumb Overfolded helix Cubitus valgus Abnormality of the thorax Pleural effusion Failure [mendelian.co]

ZTTK Syndrome

[…] to thrive in infancy, Faltering weight in infancy, Hypermetropia, Farsightedness, Hypoplasia of the corpus callosum, and Underdevelopment of part of brain called corpus callosum [globalgenes.org]

[…] collects information on symptoms that have been described in medical resources. 80%-99% of people have Global developmental delay. 30%-79% of people have Autistic behavior, Failure [globalgenes.org]

Schinzel-Giedion Syndrome

[…] to thrive in infancy Faltering weight in infancy Weight faltering in infancy [ more ] 0001531 Generalized hypertrichosis 0004554 Hydronephrosis 0000126 Hypertelorism Wide-set [rarediseases.info.nih.gov]

[…] heart morphology Abnormality of the heart Abnormally shaped heart [ more ] 0001627 Abnormality of the helix 0011039 Broad ribs Wide ribs 0000885 Facial hemangioma 0000329 Failure [rarediseases.info.nih.gov]

Hereditary Renal Cell Carcinoma

Internal blistering in the mouth and the esophagus can affect nutrition, potentially leading to failure to thrive in infancy. [epidermolysisbullosanews.com]

Congenital Disorder of Glycosylation Type 2G

[…] to thrive in infancy Faltering weight in infancy Weight faltering in infancy [ more ] 0001531 Global developmental delay 0001263 Low-set, posteriorly rotated ears 0000368 [rarediseases.info.nih.gov]

Failure to thrive in infancy MedGen UID: 358083 •Concept ID: C1867873 • Finding Midface retrusion MedGen UID: 388629 •Concept ID: C2673410 • Finding Abnormal isoelectric focusing [ncbi.nlm.nih.gov]

[…] these symptoms is not available through HPO Abnormal isoelectric focusing of serum transferrin 0003160 Autosomal recessive inheritance 0000007 Butterfly vertebrae 0003316 Failure [rarediseases.info.nih.gov]

Ehlers-Danlos Syndrome Spondylodysplastic Type 2

Caption 1: As a neonate, she required nasogastric tube feeds for failure to thrive. [epostersonline.com]

[…] to thrive in infancy Death in childhood Prolonged neonatal jaundice Hypopigmentation of hair Tetraparesis Neurodegeneration Multiple joint dislocation Platybasia Dermal atrophy [mendelian.co]

From infancy to school age, she showed progressive adipose atrophy and thinning of hair. [epostersonline.com]

Pancreatic Lipase Deficiency

The signs and symptoms of include: Failure to thrive in infancy Episodes of abdominal pain due to inflammation of the pancreas. [dovemed.com]

Failure to thrive has not been observed. [malacards.org]

[…] with colicky pain, failure to thrive, and other symptoms and signs of the chylomicronemia syndrome. [en.wikipedia.org]