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1,318 Possible Causes for Fainting Spells, Mutation in the CALM2 Gene, T Wave Alternans

  • Ventricular Arrhythmia

    spells Sometimes there are no symptoms at all.[ucsfhealth.org] T wave alternans in idiopathic long QT syndrome. J Am Coll Cardiol. 1994;23(7):1541–6. PubMed CrossRef Google Scholar 50. Napolitano C, Priori SG, Schwartz PJ.[doi.org] LQT15LQT15 is caused by heterozygous mutations in the CALM2 (Calmodulin 2) gene (114182) on chromosome 2p21.[en.wikipedia.org]

  • Long QT Syndrome

    […] case with type 3 congenital long QT syndrome, who exhibited a sudden paradoxical QT-interval prolongation during a progressive increase in heart rate, which exacerbated T-wave[ncbi.nlm.nih.gov] These fainting spells might happen when you're excited, angry, scared or during exercise.[mayoclinic.org] RESULTS: A novel de novo CALM2 mutation (D132H) was discovered by candidate gene screening in a male infant with prenatal bradycardia born to healthy parents.[ncbi.nlm.nih.gov]

  • Long QT Syndrome 10

    T-wave alternans and sinus pause corroborates this further.[ecgwaves.com] However, some patients may complain of a fluttering or palpitation in the chest before the fainting spell. Fainting spells may last for a minute or two.[news-medical.net] This prompted candidate-gene screening in a cohort of 82 LQTS genotype-negative patients. Two more patients were carriers of either CALM1 or CALM2 mutations.[smw.ch]

  • Long QT Syndrome 13

    LQTS is a heart rhythm disorder that can potentially cause fast, chaotic heartbeats, which could trigger a sudden fainting spell or seizure.[twiniversity.com] alternans [1 point] Notched T wave in 3 leads [1 point] Low heart rate for age [0.5 point] Clinical history Syncope [2 points] With stress [1 point] Without stress [1 point[athletesheart.org] This prompted candidate-gene screening in a cohort of 82 LQTS genotype-negative patients. Two more patients were carriers of either CALM1 or CALM2 mutations.[smw.ch]

  • Catecholaminergic Polymorphic Ventricular Tachycardia Type 2

    Eloff -- Diagnostic Electrocardiography / Preben Bjerregaard -- Microvolt T Wave Alternans: Mechanisms and Implications for Prediction of Sudden Cardiac Death / Florian Rader[worldcat.org] For individuals who have problems with chronic fainting spells, therapy should focus on recognizing the triggers and learning techniques to keep from fainting.[en.wikipedia.org] […] that have been discovered and only represent a small percentage of CPVT cases are TRDN (encoding triadin) and CALM1 (encoding calmodulin). 5,6 Mutations in the CALM2 gene[doi.org]

  • Ventricular Tachycardia

    Like T-wave alternans, the test is not widely used, with the exception of longitudinal evaluation of patients with suspected ARVC.[emedicine.com] spells Sometimes there are no symptoms at all.[ucsfhealth.org] Unconsciousness: Limited blood circulation may cause fainting spells or unconsciousness.[baptisthealth.com]

    Missing: Mutation in the CALM2 Gene
  • Catecholaminergic Polymorphic Ventricular Tachycardia

    This end point occurred in 48 of 361 (13%) T-wave alternans–nonnegative (positive and indeterminant) and 22 of 214 (10%) T-wave alternans–negative patients (hazard ratio,[zdoc.site] Possible complications include: Inability of the heart to pump enough blood (heart failure) Frequent fainting spells or unconsciousness Sudden death caused by cardiac arrest[mayoclinic.org] RYR2, CASQ2, KCNJ2, ANK2, CALM1, CALM2, TRDN, SCN5A* Other Panels that Include this Diagnosis Notes on Genes: Priority Genes: These genes include 70% of the mutations that[admerahealth.com]

  • Ventricular Fibrillation

    RESULTS: Frequencies of history of syncope and spontaneous type 1 ECG, r-J interval in V1, QRS duration in V6, and LAS40, Tpeak-Tend dispersion, and max T-wave alternans were[ncbi.nlm.nih.gov] In this type of test, slight changes in your electrocardiogram’s T wave are monitored during gentle exercise.[healthline.com] wave alternans 1 Notched T waves in three leads 1 Low heart rate for age (resting rate below second percentile 0.5 Clinical History Syncope With stress 2 Without stress 1[emedicine.medscape.com]

    Missing: Mutation in the CALM2 Gene
  • Long QT Syndrome 12

    After the patient returned to ICU, the ECG showed QT prolongation with large U waves and T-wave alternans.[ci.nii.ac.jp] The possible triggers that bring on the fainting spells are enquired of the patient.[news-medical.net] Treatment of long QT syndrome (LQTS) aims to prevent sudden cardiac death and similarly fatal abnormal heart rhythms and fainting spells.[news-medical.net]

    Missing: Mutation in the CALM2 Gene
  • Familial Ventricular Tachycardia

    The long QT syndrome is characterized by increased QT interval duration and the presence of T-wave alternans- an indicator for increased risk of cardiac arrhythmias.[symptoma.com] T wave may be notched- often in long QT 2 syndrome (LQT2) or have a wide base- especially in LQT1.[symptoma.com]

    Missing: Mutation in the CALM2 Gene