Possible Causes for Family History of Anemia Pernicious Anemia history of anemia or pernicious anemia Whether you have a family history of autoimmune disorders (such as Addison's disease, type 1 diabetes, Graves' disease, or vitiligo [web.archive.org] Your doctor will diagnose pernicious anemia based on your medical and family histories, a physical exam, and test results. [web.archive.org] Histories Your doctor may ask about your signs and symptoms. [web.archive.org] Hereditary Spherocytosis HS is characterized by the strong family history of anemia, jaundice, splenomegaly and cholelithiasis. [mjdrdypu.org] A detailed medical history will help uncover possible risk factors for anemia such as a family history of anemia, certain medications, chronic infection, intestinal disorders [livestrong.com] Causes Usually people with hereditary spherocytic hemolytic anemia have a family history of anemia, jaundice, or spleen enlargement (splenomegaly). [rarediseases.org] Hemoglobin C Disease A family history of anemia in the absence of iron deficiency should prompt consideration of a hemoglobinopathy, and a number of these appear in the differential diagnosis. [clinicaladvisor.com] Hemoglobin C disease is suspected in all patients with a family history and evidence of a hemolytic anemia, particularly in adults with splenomegaly. [merckmanuals.com] Homozyotes usually have a mild chronic hemolytic anemia, splenomegaly, and symptoms consistent with anemia. [merckmanuals.com] Thalassaemia-Haemoglobin C Disease Your doctor may also want to test your child if you have a family history of abnormal hemoglobin or they have anemia that’s not caused by an iron deficiency. [healthline.com] A family history of anemia in the absence of iron deficiency should prompt consideration of a hemoglobinopathy, and a number of these appear in the differential diagnosis. [clinicaladvisor.com] Hemoglobin C disease is suspected in all patients with a family history and evidence of a hemolytic anemia, particularly in adults with splenomegaly. [merckmanuals.com] Congenital Hemolytic Anemia Useful For Suggests clinical disorders or settings where the test may be helpful Providing a comprehensive genetic evaluation for patients with a personal or family history [mayomedicallaboratories.com] He is the second son of a non-consanguineous couple with unremarkable family history; there were no records of anemia, jaundice, gallstones or splenomegaly. [casesjournal.biomedcentral.com] Families with a history of spherocytosis should have their children screened for this disorder. [medlineplus.gov] Erythrocyte Membrane Abnormality Hereditary SpherocytosisDiagnosis– Must be distinguished primarily from thespherocytic hemolytic anemias associated withRBC antibodies.– If present, family history of anemia [slideshare.net] The anamnesis of a patient with HS can highlight the presence of anemia, splenectomy or gallstone in relatives, but 25% of cases have no family history. [ncbi.nlm.nih.gov] It is usually transmitted as an autosomal dominant disorder; 25% of cases are without family history. [ncbi.nlm.nih.gov] Congenital Dyserythropoietic Anemia CASE REPORT The patient was born to nonconsanguineous, healthy parents without a family history of anemia. [journals.lww.com] No family history of blood diseases was obtained and no anemia was documented in the medical records of any of her four children. [ncbi.nlm.nih.gov] Her 5-year-old brother was similarly afflicted, but there was no other family history. [ncbi.nlm.nih.gov] Hereditary Sideroblastic Anemia Family history of sideroblastic anaemia [3] There are two forms of sideroblastic anemia: congenital sideroblastic anemia and acquired sideroblastic anemia. [2] Hereditary [explainmedicine.com] history. [orpha.net] He identified cases of X-linked sideroblastic anemia in two brothers from a family with a six-generational history of the inherited disease. [encyclopedia.com] Beta Thalassaemia Major Your doctor might ask you about a family history of anemia and your child's symptoms and medicines. [kidshealth.org] Risk Factors for Thalassaemia (Mediterranean anemia; Cooley’s anemia) Family history is the only predisposing factor to this group of similiar diseases. [myvmc.com] A family history increases the risk for this disorder, which is most common in people of northern European heritage but can affect all races. [kidshealth.org] Sideroblastic Anemia Panel Description This is a next generation sequencing (NGS) test appropriate for individuals with clinical signs and symptoms, suspicion of, or family history of X-Linked [fulgentgenetics.com] The case history of two sisters with pyridoxine-refractory familial sideroblastic anemia (FSA) is presented in which one developed a myelodysplastic syndrome (MDS) with monosomy [ncbi.nlm.nih.gov] Hereditary types will be seen in younger patients with a family history while acquired sideroblastic anemia typically occurs in older patients with possible myelodysplastic [ncbi.nlm.nih.gov] Sickle Cell - Hemoglobin D Past history revealed two prior hospitalizations for fever and anemia. History of multiple blood transfusions was present. Family history was noncontributory. [imagebank.hematology.org] […] jaundice, and the family history is negative for anemia or hemolysis, then no further hematologic evaluation may be necessary. [sickle.bwh.harvard.edu] Jump to navigation Jump to search Hemoglobinopathy Screening and Hemoglobin D-Punjab Family History [ edit ] Some of the things I'm looking for in your family history include [en.wikibooks.org] Thalassemia Antenatal screening should be considered in these ethnic groups who have immigrated, especially in those with a family history of anemia. [clinicaladvisor.com] history of anemia and geographic and ethnic background, particularly if the patient comes from the Middle East, North Africa, and Southeast Asia, areas where α-thalassemia [bloodjournal.org] More severe thalassemias are suspected in patients with a family history, suggestive symptoms or signs, or microcytic hemolytic anemia. [merckmanuals.com] Hemoglobin E-Thalassemia A family history of anemia in the absence of iron deficiency should prompt consideration of a hemoglobinopathy, and a number of these appear in the differential diagnosis. [clinicaladvisor.com] A consultation with a hematologist is recommended only if a baby has signs or symptoms of anemia, or if there is a known history of a blood disorder in the family. [thalassemia.com] Thalassemia Minor history of thalassemia or anemia in both parents prior to the birth of the baby. [thalassemia.com] More severe thalassemias are suspected in patients with a family history, suggestive symptoms or signs, or microcytic hemolytic anemia. [msdmanuals.com] Risk factors for thalassemia include: Asian, Chinese, Mediterranean, or African American ethnicity Family history of the disorder The most severe form of alpha thalassemia [nlm.nih.gov] Hemoglobin Bart's Disease Antenatal screening should be considered in these ethnic groups who have immigrated, especially in those with a family history of anemia. [clinicaladvisor.com] The past medical history showed no pre- or post-natal problems. The family history was positive for Hepatitis B in the father. [pediatriceducation.org] [22] Patient Education Patients with a family history or a known carrier state for alpha thalassemia gene mutations should obtain genetic counseling to determine the genotype [emedicine.medscape.com] Sickle Cell Anemia It is recommended for families at risk for sickle cell (eg, couples with medical or family histories of anemia or of suggestive ethnic background). [msdmanuals.com] Pyruvate Kinase Deficiency A family history of congenital hemolytic anemia or anemia of childhood is typically present. [clinicaladvisor.com] A familial history of anemia may be obtamed in congenital hemolytic icterus. spheroidocytosis and inSplenomegaiy, creased fragility are characteristic. [kundoc.com] A Han Chinese child with a history of severe transfusion-dependent hemolytic anemia was diagnosed to have PK deficiency. [ncbi.nlm.nih.gov] Hemoglobinopathy Jump to navigation Jump to search Hemoglobinopathy Screening and Hemoglobin D-Punjab Family History [ edit ] Some of the things I'm looking for in your family history include [en.wikibooks.org] Tienen antecedentes de hemoglobinopatía (por ejemplo, talasemia o anemia drepanocítica). [context.reverso.net] Hb F mutations that produce an unstable Hb and hemolysis are rare, and in the absence of a family history of such a mutation, other causes should be considered first. [clinicaladvisor.com] Sickle Cell - Hemoglobin C At a Glance A family history of anemia in the absence of iron deficiency should prompt consideration of a hemoglobinopathy, and a number of these appear in the differential [cancertherapyadvisor.com] history of similar episodes Physical Vital signs Hypotension and tachycardia may be signs of septic shock or splenic sequestration crisis. [web.archive.org] The patient reported by Cook and Meyer 5 gave family history of brothers and sisters who died in early life of a disease associated with grave anemia. [doi.org] Paroxysmal Nocturnal Hemoglobinuria He reported no history of a similar condition in any of his family members or a history of hereditary anemias or hematological malignancies. [hindawi.com] Family history was only significant for a sister with sickle cell trait. [f1000research.com] […] have characteristic morphologies in the peripheral smear and positive family history [2]. [hindawi.com] Shwachman Syndrome Patients may also present with thrombocytopenia or anemia, or red cell macrocytosis, sometimes within the context of a family history of marrow failure, MDS, or AML. [cancertherapyadvisor.com] Anemia due to Glutathione Metabolism Disorder and its diagnosis should be considered in children with a family history of jaundice, anemia, splenomegaly, or cholelithiasis, especially in those of Mediterranean or African [aafp.org] X-chromosome mosaicism leading to a partial deficiency that will not be detected reliably with screening tests. 7, 11, 12 G6PD deficiency is one of a group of congenital hemolytic anemias [aafp.org] Glycogen Storage Disease Type 1 Glycogen storage disease type 1 (GSD1) is an inborn error of metabolism caused by deficiency of glucose-6-phosphatase, the enzyme catalysing the conversion of glucose-6-phosphate (G6P) to glucose. GSD1 is associated with severe hyperlipidaemia and hepatic steatosis. The underlying mechanisms responsible for these[…] [ncbi.nlm.nih.gov] Acquired Spherocytosis Blood 2015 125:3517; doi: https://doi.org/10.1182/blood-2014-12-617142 A 73-year-old man without prior personal or family history of anemia developed a chronic hemolytic anemia [bloodjournal.org] It can be helpful to specifically inquire of parents of anemic and/or jaundiced neonates about a family history of anemia, jaundice, splenectomy, or early gallstones. [pediatrics.aappublications.org] Diagnosis: Hereditary Spherocytosis (Family History) -Tests: Indirect Bilirubin, Coombs Test (negative), Osmotic Fragility -Rx: Splenectomy, Folic Acid Case #5 -History: [quizlet.com] Bacterial Pyoderma The main risk factor for furunculosis is a positive family history, but cases of anemia, previous anti-biotic therapy, diabetes mellitus, previous hospitalization, multiple [scielo.br] Microcytic Normochromic Anemia Some of the important features in medical history cover questions about family history, previous personal history of anemia or other chronic conditions, medications, color [emedicinehealth.com] Hemoglobin electrophoresis: Sometimes used when a person has a family history of anemia; this test provides information on sickle cell anemia or thalassemia. [emedicinehealth.com] On the other hand, a person with a family history of anemia and without an obvious source of blood loss may need multiple laboratory blood tests and other types of diagnostic [emedicinehealth.com] Autoimmune Disease of the Gastrointestinal Tract history of ovarian cancer Rectal masses Anemia Rectal bleeding Unintentional and unexplained weight loss A family history of bowel cancer Aged >60 years change in bowel habit [thermofisher.com] Endoscopic procedures Biopsies The potential for GI cancer should prompt referral to secondary care in patients that present the following red flag symptoms: Abdominal masses A family [thermofisher.com] Anemia Some of the important features in medical history cover questions about family history, previous personal history of anemia or other chronic conditions, medications, color [emedicinehealth.com] How is anemia diagnosed? A diagnosis of anemia begins with your health history, and that of your family, and a physical exam. [healthline.com] Hemoglobin electrophoresis: Sometimes used when a person has a family history of anemia; this test provides information on sickle cell anemia or thalassemia. [emedicinehealth.com] Vitamin B12 Deficiency Anemia history of anemia or pernicious anemia Whether you have a family history of autoimmune disorders (such as Addison's disease, type 1 diabetes, Graves' disease, or vitiligo [nhlbi.nih.gov] history of anemia. [drugs.com] Your doctor will diagnose pernicious anemia based on your medical and family histories, a physical exam, and test results. [nhlbi.nih.gov] Autoimmune Gastrointestinal Dysmotility history of ovarian cancer Rectal masses Anemia Rectal bleeding Unintentional and unexplained weight loss A family history of bowel cancer Aged >60 years change in bowel habit [thermofisher.com] Endoscopic procedures Biopsies The potential for GI cancer should prompt referral to secondary care in patients that present the following red flag symptoms: Abdominal masses A family [thermofisher.com]
