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103 Possible Causes for Family History of Anemia, Hematocrit Decreased, Reticulocytes Increased

  • Hereditary Spherocytosis

    Reticulocyte count: Increased Treatment: Splenectomy is indicated for moderate to severe cases, but not mild cases.[medical-labs.net] HS is characterized by the strong family history of anemia, jaundice, splenomegaly and cholelithiasis.[mjdrdypu.org] A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit.[en.wikipedia.org]

  • Congenital Dyserythropoietic Anemia

    On this treatment, hemoglobin and reticulocytes increased and transfusions became unnecessary.[ncbi.nlm.nih.gov] CASE REPORT The patient was born to nonconsanguineous, healthy parents without a family history of anemia.[journals.lww.com] Following delivery the infant had serial blood counts performed over a 6-week period, which noted a steady decrease in her hematocrit to 16%.[bloodjournal.org]

  • Thalassemia Minor

    […] count Normal May be slightly increased Slightly increased ( Mildly increased (5 - 10%) Mildly increased Hb electrophoresis Normal pattern Decreased amount of Hb A Variable[labce.com] history of thalassemia or anemia in both parents prior to the birth of the baby.[thalassemia.com] Abstract Patients with heterozygous beta-thalassemia minor have a decreased hematocrit (HCT).[ncbi.nlm.nih.gov]

  • Cooley's Anemia

    Children may develop dramatic, often life threatening drops in hematocrit with reticulocyte counts of nearly zero.[de.slideshare.net] Your doctor might ask you about a family history of anemia and your child's symptoms and medicines.[kidshealth.org] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org]

  • Sickle Cell Disease

    With each course, fetal reticulocytes increased within 48-72 h, peaked in 7-11 d, and fell by 18-21 d.[doi.org] It is recommended for families at risk for sickle cell (eg, couples with medical or family histories of anemia or of suggestive ethnic background).[msdmanuals.com] (p 0.001), while hemoglobin and hematocrit remained stable.[ncbi.nlm.nih.gov]

  • Congenital Hemolytic Anemia

    After partial splenectomy, children overall had decreased transfusion requirements, increased hematocrits, decreased bilirubin levels, decreased reticulocyte counts, and elimination[ncbi.nlm.nih.gov] He is the second son of a non-consanguineous couple with unremarkable family history; there were no records of anemia, jaundice, gallstones or splenomegaly.[casesjournal.biomedcentral.com] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net]

  • Pyruvate Kinase Deficiency

    Char10C mice also display a reduction in anemia phenotypes associated with the PklrG338D mutation including decreased splenomegaly, decreased circulating reticulocytes, increased[ncbi.nlm.nih.gov] A family history of congenital hemolytic anemia or anemia of childhood is typically present.[clinicaladvisor.com] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net]

  • Paroxysmal Nocturnal Hemoglobinuria

    Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] Blockade of terminal complement components presumably prolongs the survival of type III erythrocytes (since there was no simultaneous increase in reticulocytes), which are[nejm.org] Intravascular hemolysis with moderate to severe anemia, an elevated reticulocyte count, and up to a 10-fold increase in lactate dehydrogenase (LDH) is common in classical[bloodjournal.org]

  • Glycogen Storage Disease Type 1

    Glycogen storage disease type 1 (GSD1) is an inborn error of metabolism caused by deficiency of glucose-6-phosphatase, the enzyme catalysing the conversion of glucose-6-phosphate (G6P) to glucose. GSD1 is associated with severe hyperlipidaemia and hepatic steatosis. The underlying mechanisms responsible for these[…][ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Over the course of the next 5 days, the Hb and Hct decreased to 4.1 g/dL and 12%, respectively, direct bili increased to 12.3 mg/day, reticulocytes slightly increased to 0.9%[ncbi.nlm.nih.gov] […] include: Recent viral infections Taking medications that can cause autoimmune hemolytic anemia Cancer Collagen-vascular (autoimmune) disease Family history of hemolytic disease[winchesterhospital.org] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org]

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