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92 Possible Causes for Fat-Soluble Vitamin Deficiency, Obstructive Jaundice

  • Cystic Fibrosis

    soluble vitamin deficiencies (bleeding disorder, vitamin K; haemolytic anaemia, vitamin E; raised intracranial pressure, vitamin A) Infants and young children Recurrent respiratory[ncbi.nlm.nih.gov] Patients with pancreatic insufficiency have fat-soluble vitamin deficiency and malabsorption of fats, proteins, and carbohydrates (however, malabsorption of carbohydrates[emedicine.medscape.com] […] diarrhoea , constipation , or large, smelly poo a bowel obstruction in newborn babies (meconium ileus) – surgery may be needed People with the condition can also develop[nhs.uk]

  • Progressive Familial Intrahepatic Cholestasis

    The elder sibling had acute liver failure at the age of six months and both siblings had pruritus, cholestasis, coagulopathy and fat-soluble-vitamin deficiencies in infancy[ncbi.nlm.nih.gov] RESULTS: Jaundice and excessive pruritus were the main complaints.[ncbi.nlm.nih.gov] Patients with PFIC may have severe cholestasis manifest by intense pruritus, fat malabsorption and fat soluble vitamin deficiencies.[circleofmoms.com]

  • Cholangitis

    Fat-soluble vitamin deficiencies are prevented by parenteral vitamins A, D, and K(1).[ncbi.nlm.nih.gov] Secondary AIHA might not be diagnosed appropriately because the obstructive jaundice observed in type 1 AIP/IgG4-SC can obscure the presence of hemolytic jaundice.[ncbi.nlm.nih.gov] Clinical features on presentation included obstructive jaundice in 26 patients (67%) and abdominal pain in 20 (51%).[ncbi.nlm.nih.gov]

  • Primary Sclerosing Cholangitis

    Complications including portal hypertension, fat-soluble vitamin deficiency, metabolic bone diseases, and development of cancers of the bile duct or colon can occur.[doi.org] A 46-year-old woman was admitted to our hospital with obstructive jaundice. The liver function tests demonstrated increased serum liver enzyme levels.[ncbi.nlm.nih.gov] Fat Soluble Vitamin Deficiencies Vitamins A, D, E and K, are known as fat-soluble vitamins because they dissolve in oils rather than water.[patients.gi.org]

  • Cholestasis

    Presentation is usually with pruritus and the slow onset of jaundice. The term "obstructive jaundice" usually refers to cholestasis of extra-hepatic origin.[gpnotebook.co.uk] The malabsorption of fat-soluble vitamins can result in vitamin deficiency states.[emedicine.com] Jaundice. Jaundice is an uncommon occurrence in intrahepatic (metabolic) cholestasis, but is common in obstructive cholestasis. Pale stool.[en.wikipedia.org]

  • Primary Biliary Cirrhosis

    Finally, fat-soluble vitamin deficiencies are noted with more advanced disease.[ncbi.nlm.nih.gov] In 1851, Addison and Gull described the clinical picture of progressive obstructive jaundice in the absence of mechanical obstruction of the large bile ducts.[en.wikipedia.org] These engorged vessels are subject to rupture with subsequent hemorrhage that is abetted by clotting disorders. jaundice develops as a result of biliary obstruction.[medical-dictionary.thefreedictionary.com]

  • Obstructive Jaundice

    soluble vitamin deficiency (K, A, D) Elevated cholesterol - xanthomas Progressive Jaundice Gallstones Biliary cirrhosis Hepatocellular carcinoma[meddean.luc.edu] Its presence can lead to a multitude of presentations, one of the rarer ones being obstructive jaundice due to migration of the worm in to the biliary tree.[ncbi.nlm.nih.gov] In addition, the fat- soluble vitamins A, D, E, and K are not absorbed, resulting in vitamin deficiencies. • Disordered hemostasis with an abnormally prolonged PT may further[slideshare.net]

  • Extrahepatic Cholestasis

    As a result of inadequate bile in the GI tract, there is malabsorption of fat and fat-soluble vitamins (A, D, E, and K), leading to vitamin deficiency, inadequate nutrition[merckmanuals.com] We conclude that it is not necessary to adjust single doses of MCL in patients recovering from obstructive jaundice.[ncbi.nlm.nih.gov] Abstract Obstructive jaundice occurs in patients suffering from cholelithiasis and from neoplasms affecting the pancreas and the common bile duct.[ncbi.nlm.nih.gov]

  • Secondary Biliary Cirrhosis

    Patients will display the general clinical features of cholestasis such as pruritis, xanthomas, jaundice, steatorrhea, and deficiencies of the fat soluble vitamins A, D, E[pathwaymedicine.org] In such a case presenting as persisting and fluctuating obstructive jaundice in HCC, an intrabile duct tumor growth should be suspected.[jpatholtm.org] Screen for esophageal varices, osteoporosis, fat-soluble vitamin deficiency, and hypothyroidism.[clevelandclinicmeded.com]

  • Bile Duct Disease

    This disorder has also been reported in infants who present with severe fat and fat-soluble vitamin deficiencies and mild cholestasis.[rarediseases.org] Bile Duct Tumors — many people with bile duct tumors have jaundice due to the tumor obstructing the bile ducts.[froedtert.com] Jaundice Portal Hypertension Cancer can block the bile ducts, which carry bile from the liver to the small intestine to help digest fats.[nyp.org]

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