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706 Possible Causes for Fatigue, Foot Drop

  • Idiopathic Pulmonary Fibrosis

    The progression of IPF lead to a decline in forced vital capacity (FVC), dyspnea, cough, continuous sleep interruptions, resulting in increased fatigue and deteriorating quality[ncbi.nlm.nih.gov] Abstract A 58-year-old man with a 15-year history of idiopathic pulmonary fibrosis was hospitalized for rapid progression of muscle weakness to bilateral foot drop.[ncbi.nlm.nih.gov] Almost all patients reported at least one adverse event, and more patients on interferon gamma-1b group had constitutional signs and symptoms (influenza-like illness, fatigue[ncbi.nlm.nih.gov]

  • Multifocal Motor Neuropathy

    This study is the first to show that activity-dependent conduction block plays a role in human disease by causing muscle fatigue.[ncbi.nlm.nih.gov] Clinically, it is characterized by slowly progressive asymmetrical predominantly distal weakness; unilateral wrist drop, grip weakness, and foot drop are the commonest initial[ncbi.nlm.nih.gov] Wrist drop and foot drop (leading to trips and falls) are common symptoms. Other effects can include gradual loss of finger extension, leading to a clawlike appearance.[en.wikipedia.org]

  • Amyotrophic Lateral Sclerosis

    All studies assessed fatigue using the Fatigue Severity Scale (FSS; scale from 9 to 63, higher scores indicate more fatigue).[ncbi.nlm.nih.gov] This usually begins on one side of the body and can cause loss of hand dexterity, shoulder function, a foot-drop or walking difficulty.[alsbc.ca] The patient may develop foot drop resulting in a fall or sprain. Fasciculations may present early on in the disease, particularly in the tongue.[emedicine.com]

  • Chronic Kidney Insufficiency

    In fact, drowsiness, fatigue, and an overall lack of energy are encountered in the majority of patients, along with pruritus and pain.[symptoma.com] Symptoms develop slowly and in advanced stages include anorexia, nausea, vomiting, stomatitis, dysgeusia, nocturia, lassitude, fatigue, pruritus, decreased mental acuity,[merckmanuals.com] End stage renal disease causes weight loss, nausea and vomiting, fatigue, difficulty breathing and seizures.[kidneyandhypertensioncare.com]

  • Connective Tissue Disease

    Connective Tissue Disease Symptom Fatigue Fatigue can be described as the lack of energy and motivation (both physical and mental).[medicinenet.com] Signs and symptoms Frequent falls Difficulty walking Trouble climbing stairs or standing from a seated position A foot that seems to drop when walking, causing tripping Weakened[myositis.org] Polymyositis presents with symptoms such as fatigue, muscle weakness, weight loss, shortness of breath and difficulty in swallowing food.[symptoma.com]

  • Cachexia

    Fatigue The terms “asthenia” and “fatigue” are often used interchangeably.[aafp.org] Adopting uniform reporting mechanisms for fatigue outcome measures, such as the Multidimensional Assessment of Fatigue (MAF) scale or the Piper Fatigue Scale ( Dittner 2004[doi.org] The rapid assessment of fatigue severity in cancer patients: use of the Brief Fatigue Inventory. Cancer 1999;85:1186–96 . Brief Fatigue Inventory FIGURE 1.[aafp.org]

  • Neuropathy

    Postoperative range of motion exercises and physical therapy allowed resolving foot drop 1 year after surgery. Copyright 2017 Elsevier Inc. All rights reserved.[ncbi.nlm.nih.gov] […] with challenges engage in life, either through rehabilitating or through teaching them how to adapt how they conduct daily activities, such as getting dressed, managing fatigue[curetoday.com] Injury to the common peroneal nerve results in foot drop and inversion (turning inward) of the foot.[vermontspineworks.com]

  • Osteoporosis

    , since bisphosphonates inhibit bone remodeling, they may enhance the formation and propagation of micro-cracks over time and patients may therefore be prone to atypical fatigue[ncbi.nlm.nih.gov] […] levels have dropped too low during the night, when you are not consuming food.[betterbones.com] […] court seems likely to side with Merck in Fosamax case," 7 Jan. 2019 Symptoms can range in severity and include osteoporosis , kidney stones, excessive peeing, stomach pain, fatigue[merriam-webster.com]

  • Guillain-Barré Syndrome

    Guillain-Barré syndrome (GBS) encompasses a broad spectrum of health-related quality of life (HRQL) determinants, including mobility, fatigue, pain, and depression.[ncbi.nlm.nih.gov] 23 January 2014 Cited by: 6 Abstract Guillain‐Barré syndrome (GBS) encompasses a broad spectrum of health‐related quality of life (HRQL) determinants, including mobility, fatigue[doi.org] In addition, many patients have pain and fatigue that can persist for months or years.[ncbi.nlm.nih.gov]

  • Chronic Inflammatory Demyelinating Polyneuropathy

    We present a patient with CIDP in whom fatigue remained the only symptom, hereby stressing the importance of adding this disease to the differential diagnosis of fatigue.[ncbi.nlm.nih.gov] drop and recurrent upper extremity paresthesias.[ajnr.org] Fatigue Loss of reflexes Tingling Numbness Pain Weakness Paralysis The degree of symptom severity varies with each individual.[peripheralneuropathycenter.uchicago.edu]

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