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1,391 Possible Causes for Fatigue, Headache, HLA-B27, Spondylitis

  • Whipple Disease

    We report a 54-year-old woman who presented subacutely with fever, headache, and seizures that led to a diagnosis of infectious meningoencephalitis.[ncbi.nlm.nih.gov] Differential diagnosis The differential diagnosis includes seronegative polyarthritis, ankylosing spondylitis, culture-negative endocarditis, vasculitis, malabsorption syndrome[orpha.net] Abstract A 72-year-old man presented with a 6-month history of dysphagia, fatigue, 60-lb weight loss, and central nervous system (CNS) deficits.[ncbi.nlm.nih.gov] About 30% of patients have HLA-B27. Drugs Mentioned In This Article PLAQUENIL No US brand name ROCEPHIN PERIOSTAT, VIBRAMYCIN[merckmanuals.com]

  • Enthesitis-Related Arthritis

    The most common AE (no. events, events per 100 patient-yrs) overall were headache (23, 10.7), pyrexia (12, 5.6), and diarrhea (10, 4.6).[ncbi.nlm.nih.gov] The presence of HLA-B27 has a strong association with JIA-ERA similar to that with adult ankylosing spondylitis (AS). The HLA-B27gene is highly polymorphic.[ncbi.nlm.nih.gov] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 13, 2019[patientslikeme.com] Runny nose, pain at the injection site, mild bruising, and occasional headache have all been reported; for a child who is doing dramatically better on the drug, these are[hss.edu]

  • Ankylosing Spondylitis

    Headache or Migraine... What to do? Heat Packs. Why does heat feel so good? How to Achieve the Best Standing Posture Neck Headache?[physioworks.com.au] What causes ankylosing spondylitis? The cause of ankylosing spondylitis (AS) is unknown.[niams.nih.gov] GETTY Ankylosing spondylitis: Symptoms include fatigue Ankylosing spondylitis causes back pain, stiffness and fatigue A total of five factors were identified as independent[express.co.uk] In literature, although the evidence for association between AS and periodontitis as well as AS and HLA-B27 are there but the association of aggressive periodontitis in HLA-B27[ncbi.nlm.nih.gov]

  • Spondylitis

    Clinically, several groups of symptoms, both overlapping and distinct, are seen: neck and shoulder pain, suboccipital pain and headache, radicular symptoms, and cervical spondylotic[askdrshah.com] Types of spondylitis include cervical spondylitis – which affects the cervical spine, causing pain to spread the back of the neck; lumbar spondylitis – which causes pain in[en.wikipedia.org] "This can make you excessively fatigued.”[everydayhealth.com] Many HLA-B27 positive don’t get AS, and some people without it do. Prevalence 2-8% (30% in eskimos!)[oxfordmedicaleducation.com]

  • Psoriatic Arthritis

    Side effects of Otezla include diarrhea, nausea, vomiting, upper respiratory tract infection, runny nose, sneezing, or congestion, abdominal pain, tension headache, and headache[otezla.com] Psoriatic arthritis Reiter’s syndrome As with ankylosing spondylitis and Reiter’s syndrome, bone proliferation is a major feature.[learningradiology.com] The causes of this debilitating fatigue are multifaceted; coexisting conditions such as fibromyalgia or depression can be one of them, as they arouse fatigue in many cases[psoriasis.qualitycarebyleo.com] While a number of genes are linked to PsA, the highest predictive value is noted with HLA-B27.[spondylitis.org]

  • Uveitis

    RESULTS: A 30-year-old man presented with headaches, ocular pain, photophobia, and blurred vision.[ncbi.nlm.nih.gov] The most common diagnosis was juvenile idiopathic arthritis-related uveitis (n   10), followed by Behçet's disease (n   4), sarcoidosis (n   1), and ankylosing spondylitis[ncbi.nlm.nih.gov] For example, the presence of painful joints, weight changes, skin rashes, fatigue, and other symptoms may help the doctor diagnose an underlying illness that may be associated[medicinenet.com] Half of all cases of AAU are HLA-B27 positive.[doi.org]

  • Iritis

    Common symptoms include: Pain Sensitivity to light Decreased vision Red eye Headache Irregularly shaped pupils Treatment varies but can include the administration of steroids[westmichiganeye.com] Abstract A case of foveomacular retinitis, ankylosing spondylitis, iritis, and iris dissociation is described.[ncbi.nlm.nih.gov] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: March 31, 2019[patientslikeme.com] The increased incidence of iritis may be due to increased frequency of HLA B27 genes in the population.[symptoma.com]

  • Juvenile Ankylosing Spondylitis

    Inflamed knees, headaches and feeling bloated are things I can live without. If I can change my diet and feel this amazing, anyone can.[robbwolf.com] Abstract The clinical histories and radiographs of 28 patients with ankylosing spondylitis were reviewed. Symptoms developed before the age of 17 in all cases.[ncbi.nlm.nih.gov] Fatigue was reported by 98% of patients with autoimmune disorders polled, and fatigue that prevented completion of everyday tasks was reported by 68% of the patients, according[healio.com] Nine of the 10 patients exhibited the genetic marker HLA B27, but only one patient was homozygous for HLA B27.[ncbi.nlm.nih.gov]

  • Polymyalgia Rheumatica

    Tension-type headache mimics. Curr Pain Headache Rep 2011;15:459-66.[doi.org] […] tablets (1 mg, 2 mg and 5 mg) to treat a broad range of diseases including rheumatoid arthritis (RA), polymyalgia rheumatica (PMR), psoriatic arthritis (PsA), ankylosing spondylitis[news-medical.net] Associated symptoms include low-grade fever, malaise, fatigue, low mood, poor appetite, and weight loss.[ncbi.nlm.nih.gov] Rheumatologic markers, and HLA-B27 were checked.[ncbi.nlm.nih.gov]

  • Herpes Zoster

    KEYWORDS: headache (including migraines); pain (neurology)[ncbi.nlm.nih.gov] […] reported that the crude incidence rate of HZ among anti-TNF users is 4.4 per 1000 patient-years for autoimmune diseases such as psoriasis, psoriatic arthritis, and ankylosing spondylitis[doi.org] There were no significant differences between groups for the following AEs: any grade 3 symptom, any general symptom, any general grade 3 symptom, fatigue, grade 3 fatigue[doi.org] HIV 1 susceptibility is associated with the presence of C-protein–coupled 7-transmembrane coreceptors such as CCR5 and CCR2 and suppressive chemokines such as CCL3L1. 11 HLA-B27[dx.doi.org]

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