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176 Possible Causes for Fatigue, Hematocrit Decreased, Reticulocytes Increased

  • Hereditary Spherocytosis

    Reticulocyte count: Increased Treatment: Splenectomy is indicated for moderate to severe cases, but not mild cases.[medical-labs.net] A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit.[en.wikipedia.org] Pediatric patients with lower scores on physical well-being experienced more fatigue.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    The percentage of reticulocytes is mildly increased but may vary widely in a given case.[patient-help.com] […] the hematocrit, but not the WBC count.[clevelandclinicmeded.com] The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Over the course of the next 5 days, the Hb and Hct decreased to 4.1 g/dL and 12%, respectively, direct bili increased to 12.3 mg/day, reticulocytes slightly increased to 0.9%[ncbi.nlm.nih.gov] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org] Subsequently, he was admitted to our hospital owing to fatigue, a high fever, and jaundice.[ncbi.nlm.nih.gov]

  • Thalassemia Minor

    […] count Normal May be slightly increased Slightly increased ( Mildly increased (5 - 10%) Mildly increased Hb electrophoresis Normal pattern Decreased amount of Hb A Variable[labce.com] Abstract Patients with heterozygous beta-thalassemia minor have a decreased hematocrit (HCT).[ncbi.nlm.nih.gov] Abstract Beta-thalassemia minor (BTM) patients usually experience fatigue, bone pain complaint, and muscle weakness.[ncbi.nlm.nih.gov]

  • Cold Agglutinin Disease

    Typical bloodwork results would show: decreased hemoglobin (due to the red cell lysis) increased reticulocyte count (reflecting the marrow kicking red cell production into[transfusion.ca] The MCHC and MCH values will be increased due to decreased hematocrit and RBC count. Other causes of invalid red cell indices have to be ruled out.[keralamedicaljournal.com] Cold agglutinin disease manifests as acute or chronic hemolytic anemia, with associated pallor and fatigue.[web.archive.org]

  • Cooley's Anemia

    Children may develop dramatic, often life threatening drops in hematocrit with reticulocyte counts of nearly zero.[de.slideshare.net] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org] Fatigue and being short of breath are two of the more common symptoms. The individual is also likely to be somewhat pale, possibly exhibiting signs of jaundice .[wisegeek.com]

  • Sickle Cell Disease

    With each course, fetal reticulocytes increased within 48-72 h, peaked in 7-11 d, and fell by 18-21 d.[doi.org] Sickled cells lose their normal functioning and hemodynamic properties, leading to chronic fatigue as well as to episodes of painful crises.[ncbi.nlm.nih.gov] (p 0.001), while hemoglobin and hematocrit remained stable.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] Functional Assessment of Chronic Illness Therapy‐Fatigue (FACIT‐Fatigue).[doi.org] Blockade of terminal complement components presumably prolongs the survival of type III erythrocytes (since there was no simultaneous increase in reticulocytes), which are[nejm.org]

  • Hodgkin Lymphoma

    On the symptom scales, higher mean scores, exceeding 10 points, were obtained for the scales "Fatigue" and "Sleep".[ncbi.nlm.nih.gov] A 28-year-old man with a history of Hodgkin disease in remission had fatigue, pyrexia, and a raised ESR.[ncbi.nlm.nih.gov] A 60-year-old woman presented to her primary care physician with fatigue and anemia.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com] On initial presentation she reported fatigue, night sweats, and early satiety, and was found to have a white blood cell (WBC) count of 69.3 109 /L and platelet count of 366[ncbi.nlm.nih.gov] The majority of patients are diagnosed in the chronic phase and may be either asymptomatic (diagnosed through a routine white blood cell count) or present with fatigue, anaemia[orpha.net]

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