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40 Possible Causes for Fatigue, Hepatomegaly, Physiological Neonatal Jaundice

  • Liver Cirrhosis

    Cardinal symptoms include fasting hypoglycemia, lactic acidosis and hepatomegaly as well as neutropenia.[ncbi.nlm.nih.gov] In the presented case, the authors describe an obese middle-aged man that presented to the emergency department for persistent oedema, scleral icterus and fatigue.[ncbi.nlm.nih.gov] […] history of alcohol excess, neonatal jaundice, hypertension, or hypercholesterolemia.[atsjournals.org]

  • Galactosemia

    Galactosemia in newborns and infants is associated with the following symptoms: jaundice, hepatomegaly, failure to thrive, feeding difficulties, hypoglycemia, convulsions,[ncbi.nlm.nih.gov] […] is yellowing of the skin and other parts of the body liver enlargement liver damage fluid building up in the abdomen and swelling abnormal bleeding diarrhea irritability fatigue[healthline.com] Applicable To Neonatal physiological jaundice (intense)(prolonged) NOS due to or associated with galactosemia E74.21 ICD-10-CM Codes Adjacent To E74.21 E74.09 Other glycogen[icd10data.com]

  • Cardiac Cirrhosis

    Hepatomegaly Hepatomegaly is common, usually presenting as a firm, hard liver.[emedicine.medscape.com] Chronic hepatitis: fatigue, discomfort, loss of appetite, nausea and abdominal pain (right hypochondrium). Associated with thyroid disorders.[mediktor.com] Congestive hepatopathy is suspected in patients who have right-sided heart failure, jaundice, and tender hepatomegaly.[merckmanuals.com]

  • Jaundice

    Abdominal ultrasonography showed hepatomegaly and a thickened gallbladder wall.[ncbi.nlm.nih.gov] Symptoms include fatigue, dark urine, pale skin and gums, rapid heart rate, shortness of breath, yellowing of skin or the whites of the eyes.[healthline.com] This is called “physiologic” or normal neonatal jaundice. Most infants have this pattern so no testing is needed.[patients.gi.org]

  • Hereditary Spherocytosis

    Pallor (100%), icterus (67%), undocumented fever (28%), splenomegaly (96%) and hepatomegaly (73%) were the most frequent findings. Cholelithiasis was observed in 26%.[ncbi.nlm.nih.gov] Pediatric patients with lower scores on physical well-being experienced more fatigue.[ncbi.nlm.nih.gov] Applicable To Neonatal physiological jaundice (intense)(prolonged) NOS spherocytosis D58.0 (congenital) Spherocytosis (congenital) (familial) (hereditary) D58.0 hemoglobin[icd10data.com]

  • Obesity

    Obesity increases the risk for alterations in hepatocyte function that lead to accumulation of lipid in hepatocytes and hepatomegaly.[library.med.utah.edu] Smith and Dorothy Williams, Obesity in Urban Women: Associations with Sleep and Sleepiness, Fatigue and Activity, Women's Health Issues, 24, 4, (e447), (2014). M.[doi.org] […] effects of infection and, in one case, neonatal death.[doi.org]

  • Extrahepatic Cholestasis

    Clinically it present with jaundice, vomiting, hepatomegaly, hypoglycemia and intolerance to lactose containing formula.[saudijgastro.com] Overly fatigue. Although this kind of feeling is very normal during pregnancy, cholestasis can also result fatigue because of the role of the liver in your metabolism.[webmedicinecenter.com] Whereas physiologic jaundice constitutes a common finding in neonates, a few cases present with cholestatic jaundice owing to various pathologic conditions, including extrahepatic[ncbi.nlm.nih.gov]

  • Neonatal Jaundice

    In these disorders, the clinical presentation includes jaundice, pale stools, dark urine and hepatomegaly.[ncbi.nlm.nih.gov] Symptoms include fatigue, dark urine, pale skin and gums, rapid heart rate, shortness of breath, yellowing of skin or the whites of the eyes.[healthline.com] Jaundice, Physiological NeonatalNeonatal Jaundice, Physiological — Severe Jaundice in Newborn — Severe Jaundice in Neonate — Icterus Gravis Neonatorum[mesh.kib.ki.se]

  • Indian Childhood Cirrhosis

    On examination, he had hepatosplenomegaly with firm hepatomegaly and a leafy border. There were no other signs of liver cell failure.[pediatriconcall.com] May be asymptomatic or complain of fatigue, pruritus, and non-jaundice skin hyperpigmentation with hepatomegaly.[gutenberg.us] It typically presents with transient neonatal jaundice, in a child who is otherwise healthy, and progresses to biliary cirrhosis and portal hypertension.[ncbi.nlm.nih.gov]

  • Acquired Immunodeficiency Syndrome

    Hepatomegaly and/or splenomegaly was noted among 26% of patients.[web.archive.org] Fatigue was defined by patient self-report. The outcomes were the prevalence of fatigue and the potential risk factors of fatigue.[ncbi.nlm.nih.gov] Other serious events included birth‐related conditions (14 with ZDV versus 6 with NVP), physiological jaundice (10 with ZDV versus 5 with NVP) and neonatal septicaemia (7[doi.org]

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