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358 Possible Causes for Fatigue, Hypercellular Bone Marrow

  • Chronic Myeloid Leukemia

    On initial presentation she reported fatigue, night sweats, and early satiety, and was found to have a white blood cell (WBC) count of 69.3 109 /L and platelet count of 366[ncbi.nlm.nih.gov] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] The majority of patients are diagnosed in the chronic phase and may be either asymptomatic (diagnosed through a routine white blood cell count) or present with fatigue, anaemia[orpha.net]

  • Polycythemia Vera

    Read more: 10 Quick Ways to Boost Energy and Fight Fatigue[livestrong.com] bone marrow 5.[slideshare.net] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    By using the Functional Assessment of Chronic Illness Therapy Fatigue instrument (scores can range from 0 to 52, with higher scores indicating improvement in fatigue), the[ncbi.nlm.nih.gov] Bone marrow failure is present in all patients with PNH, even when peripheral blood counts are normal and the bone marrow is hypercellular.[emedicine.medscape.com] Furthermore, the patient showed significant improvements in fatigue scale scores and quality of life.[ncbi.nlm.nih.gov]

  • Acute Leukemia

    The initial manifestations of leukemia are generally signs of bone marrow failure, such as pallor, fatigue, fever, bleeding, and infection related to peripheral blood cytopenias[ncbi.nlm.nih.gov] ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] […] and perceived fatigue [ 30 ].[journals.plos.org]

  • Myeloproliferative Disease

    We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: December 1, 2018[patientslikeme.com] The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net]

  • Chronic Phase of Chronic Myeloid Leukemia

    In the accelerated phase, the number of CML cells is growing faster and causing symptoms such as fatigue, fever, weight loss and an enlarged spleen.[lls.org] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] People in this phase may notice symptoms like fatigue, caused by a lower number of red blood cells, and stomach pain due to an enlarged spleen.[healthline.com]

  • Hairy Cell Leukemia

    Hairy cell leukemia (HCL) is a rare type of indolent B-cell leukemia, characterized by symptoms of fatigue and weakness, organomegaly, pancytopenia, and recurrent opportunistic[ncbi.nlm.nih.gov] Fig. 2: TRAP ; Fig. 3: hypercellular bone marrow with monotonous "fried egg" lymphocytes with abundant cytoplasm Cytology description Small / intermediate size cells with[pathologyoutlines.com] During interferon-α therapy she developed multiple subcutaneous swellings, accompanied by fever and fatigue.[ncbi.nlm.nih.gov]

  • Autoimmune Gastritis

    There was symptomatic improvement in her signs of fatigue.[ncbi.nlm.nih.gov] marrow Hypercellular bone marrow Increased erythroid precursors Open, immature nuclear chromatin Dyssynchrony between maturation of cytoplasm and nuclei Giant bands, metamyelocytes[wjgnet.com] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: November 22, 2018[patientslikeme.com]

  • Sickle Cell Disease

    Sickled cells lose their normal functioning and hemodynamic properties, leading to chronic fatigue as well as to episodes of painful crises.[ncbi.nlm.nih.gov] […] case of a 7-year-old Cameroonian girl with sickle cell disease (SCD) who presented with progressive abdominal distension, fever, severe anemia, respiratory distress, and fatigue[ncbi.nlm.nih.gov] Low-grade nausea, noncardiac chest pain, fatigue, and musculoskeletal pain occurred more frequently in the l-glutamine group than in the placebo group.[ncbi.nlm.nih.gov]

  • Cryptogenic Organizing Pneumonia

    We report on the case of a previously healthy 10-year-old girl who consulted her doctor for a 2-month history of mild pyrexia, fatigue, weight loss, and exertional dyspnea[ncbi.nlm.nih.gov] Other pathologic changes were pleural effusion (left, 800 ml: right, 1200 ml), acute liver congestion, prostatic hypertrophy, colon adenoma, and hypercellular bone marrow.[ncbi.nlm.nih.gov] Cough, fatigue and dyspnea were the most common symptoms on admission.[ncbi.nlm.nih.gov]

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