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9,198 Possible Causes for Fatigue, Leukocyte Alkaline Phosphatase Increased, Wide Space Between the First and Second Toe

  • Down Syndrome

    The most commonly reported side effects were "diarrhoea, fatigue, insomnia, nausea and vomiting" (page 497; Prasher 2005 ).[doi.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] The other five patients positive for IgA-EMAs had gastrointestinal symptoms typical of celiac disease, including bulky stools, failure to thrive, fatigue, and personality[journals.lww.com]

  • Non-Hodgkin Lymphoma

    The patient was a 77-year-old man with history of symptoms of partial bowel obstruction, intermittent right iliac fossa pain, loss of weight, vomiting and fatigue.[ncbi.nlm.nih.gov] The most frequently reported ( 20%) adverse events of any grade in the population in which safety was studied were hyperglycemia, fatigue, and nausea (36.1% each), depression[ncbi.nlm.nih.gov] […] with selinexor at 35 or 60 mg/m 2 The most common grade 3 to 4 drug-related adverse events were thrombocytopenia (47%), neutropenia (32%), anemia (27%), leukopenia (16%), fatigue[ncbi.nlm.nih.gov]

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  • Leukoerythroblastic Anemia

    alkaline phosphatase (LAP) score is increased Treatment Reduced intensity allogeneic stem cell transplant if intermediate to high risk or palliation of extramedullary hematopoiesis[pathologyoutlines.com] Case Report: A 65-year-man presented to our hospital with 6 weeks of increasing fatigue, 20-lb weight loss, and temperature of up to 100.8 F.[annals.org] Persons with anemia may feel tired and fatigue … Medical dictionary leukoerythroblastosis — Any anemic condition resulting from space occupying lesions in the bone marrow;[medicine.academic.ru]

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  • Aplastic Anemia

    Fatigue is the most common presentation as it is the first symptom of low red blood cell count. Fatigue also sets in when there is a lack of hemoglobin in the blood.[symptoma.com] Call if you notice frequent infections or unusual fatigue. Hypoplastic anemia; Bone marrow failure - aplastic anemia Bagby GC.[nlm.nih.gov] Patients are left fatigued and highly vulnerable to many kinds of infections as well as excessive and uncontrollable bleeding.[symptoma.com]

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  • Myeloproliferative Disease

    A myeloproliferative disorder manifested by thrombocytosis, a high leukocyte alkaline phosphatase (LAP) score and an increased red blood cell mass was found in a 64-yr-old[ncbi.nlm.nih.gov] Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net] Leukocyte alkaline phosphatase ( 100 units in the absence of fever or infection). There is no staging system for this disease.[northshore.org]

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  • Primary Myelofibrosis

    alkaline phosphatase (LAP) score is increased Treatment Reduced intensity allogeneic stem cell transplant if intermediate to high risk or palliation of extramedullary hematopoiesis[pathologyoutlines.com] The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] In this paper we present a case of a 47-year-old male patient who was admitted to the hospital with symptoms of fatigue and small amount of urine, and clinical signs of plethora[ncbi.nlm.nih.gov]

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  • Liver Failure

    One month before this visit, he was noted to have poor appetite and progressive fatigue.[ncbi.nlm.nih.gov] […] episode, the family suffered gastrointestinal symptoms which were self-limited except in the child's case, who was admitted to hospital in Uruguay with diarrhea, vomiting, fatigue[ncbi.nlm.nih.gov] These signs may include fatigue, nausea, diarrhea, and discomfort in your right side, just below your ribs.[hopkinsmedicine.org]

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  • Viral Hepatitis

    This is followed by the prodromal period, which is characterized by acute manifestations such as fatigue, malaise, fever, anorexia, nausea, emesis, abdominal pain, urticaria[symptoma.com] Symptoms of acute (newly acquired) hepatitis include: fever, fatigue, loss of appetite, nausea, vomiting, abdominal/stomach pain, dark urine, clay-colored feces, joint pain[dph.georgia.gov] The most frequently reported symptom was fatigue (73.7%), and the most common complications were cholecystitis (0.4%) and fulminant hepatitis (0.4%).[ncbi.nlm.nih.gov]

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  • Polycythemia Vera

    leukocyte alkaline phosphatase , increased vit.B12 level, decreased folic acid level, elevated alk.phosphatase & conjungated bilirubin, hypercalcemia.[enotes.tripod.com] Regardless of baseline iron status, treatment with ruxolitinib was associated with improvements in concentration problems, cognitive function, dizziness, fatigue, headaches[ncbi.nlm.nih.gov] 79.5%) patients experienced momelotinib-related adverse events (AEs), the most frequent being headache (23.1%), dizziness (18.0%), somnolence (15.4%), nausea (15.4%), and fatigue[ncbi.nlm.nih.gov]

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  • Inflammatory Bowel Disease Type 1

    A 53-year-old man with Crohn's disease treated with adalimumab was hospitalised with abdominal pain, fatigue, fever and chills.[ncbi.nlm.nih.gov] The symptoms of the non-IBS prodrome in subjects with Crohn's disease were bloating, diarrhea, stomach pain, heartburn, fever, weight loss, and fatigue.[ncbi.nlm.nih.gov] It causes inflammation of your digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition.[mayoclinic.com]

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