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505 Possible Causes for Fatigue, Muscular Atrophy, Numbness of the Feet

  • Chronic Inflammatory Demyelinating Polyneuropathy

    Peroneal muscular atrophy (PMA) and related disorders. I. Clinical manifestations as related to biopsy findings, nerve conduction and electromyography.[doi.org] We present a patient with CIDP in whom fatigue remained the only symptom, hereby stressing the importance of adding this disease to the differential diagnosis of fatigue.[ncbi.nlm.nih.gov] CIDP often causes limb weakness but may just cause problems with balance from numbness in the feet and legs.[phoenixneurology.com]

  • Transverse Myelitis

    A bandlike tightness around the chest or abdomen, weakness, tingling, numbness of the feet and legs, and difficulty voiding develop over hours to a few days.[msdmanuals.com] Doug was the global lead for a series of programs in Alzheimer’s disease, Amyotrophic Lateral Sclerosis (ALS) and Spinal Muscular Atrophy (SMA).[myelitis.org] The patient reported a reduction in pain, dyspnea, and fatigue accompanied by an improvement in the quality of sleep and mood.[ncbi.nlm.nih.gov]

  • Peripheral Neuropathy

    Muscular atrophy of hand muscles persisted. Large fibers were involved more extensively than small fibers.[ncbi.nlm.nih.gov] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: January 30, 2019[patientslikeme.com] Numbness in the feet can lead to skin sores that do not heal. In rare cases, numbness in the feet may lead to amputation.[nlm.nih.gov]

  • Primary Progressive Multiple Sclerosis

    In late-stage Roche, they have treatments that are being tested for Alzheimer’s disease, Autism, and for Spinal Muscular Atrophy.[mdmag.com] Numbness/tingling Another early symptom of PPMS is numbness or tingling in various body parts, such as your face, hands, and feet.[healthline.com] Roche has more than a dozen investigational medicines in clinical development for diseases that include multiple sclerosis, Alzheimer’s disease, spinal muscular atrophy, Parkinson[finance.yahoo.com]

  • Amyloidosis

    After one year, her symptoms of fatigue became worse, and her proteinuria increased.[ncbi.nlm.nih.gov] Symptoms may include any of the following: Abnormal heart rhythm Fatigue Numbness of hands or feet Shortness of breath Skin changes Swallowing problems Swelling in the arms[medlineplus.gov] Numbness or lack of feeling in the toes or feet Weakness in the legs, which can be a result of nerves irritated by the amyloid Diseases that are associated with amyloidosis[cedars-sinai.edu]

  • Celiac Disease

    atrophy Headache Hypertransaminasemia Anemia Pubertal delay Extraintestinal symptoms A tendency towards lower clinical manifestations can be observed as age increases[ 4[dx.doi.org] Bilateral non traumatic femoral neck fatigue fracture is a rare condition usually occurring secondary to medical conditions such as pregnancy, pelvic irradiation, corticosteroid[ncbi.nlm.nih.gov] A 60-year-old man, without any gastrointestinal symptoms, developed over the course of one week rapidly progressive gait imbalance, tingling and numbness in his feet and ascending[ncbi.nlm.nih.gov]

  • Hereditary ATTR Amyloidosis

    atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial.[researchmap.jp] […] including: Shortness of breath Labored breathing during exercise Peripheral swelling ( edema caused by a buildup of fluid in the lower limbs) Fainting ( syncope ) Generalized fatigue[pfizer.com] Numbness or lack of feeling in the toes or feet Weakness in the legs, which can be a result of nerves irritated by the amyloid Diseases that are associated with amyloidosis[cedars-sinai.edu]

  • Diabetes Mellitus Type 1

    Patients experience the following: Increased thirst Increased hunger Increased urination Fatigue Blurry vision Rapid weight loss in a short amount of time Hunger Neurologic[symptoma.com] A patient may have heart disease, chronic infections of the gums and urinary tract, blurred vision, numbness in the feet and legs, or slow-healing wounds.[medical-dictionary.thefreedictionary.com] Increased appetite) Glycosuria (glucose in urine) Weight loss despite polyphagia Hyperglycemia (increased blood glucose) Ketonuria (ketones in urine) Fruity smelling breath Fatigue[physio-pedia.com]

  • Neuropathy

    Types I and II (varieties of Charcot-Marie-Tooth disease, also called peroneal muscular atrophy) are the most common; they are usually autosomal dominant disorders but can[merckmanuals.com] Another side of neuropathy, and probably the worse, is "fatigue." For months it was difficult to function.[spacedoc.com] Numbness in the feet can lead to skin sores that do not heal. In rare cases, numbness in the feet may lead to amputation.[nlm.nih.gov]

  • Multifocal Motor Neuropathy

    In addition to muscle weakness, there can be fatigue, pain, numbness, lack of balance, sight and hearing.[aanem.org] Abstract Multifocal motor neuropathy (MMN) and progressive muscular atrophy (PMA) are associated with IgM monoclonal gammopathy or the presence IgM anti-GM1-antibodies.[ncbi.nlm.nih.gov] This study is the first to show that activity-dependent conduction block plays a role in human disease by causing muscle fatigue.[ncbi.nlm.nih.gov]

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