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12 Possible Causes for Fatigue, Pancytopenia, Wide Space Between the First and Second Toe

  • Down Syndrome

    Since the circulating blast count is often low in ML-DS and the predominant haematological picture may be of slowly progressive pancytopenia, a bone marrow aspirate is usually[doi.org] The most commonly reported side effects were "diarrhoea, fatigue, insomnia, nausea and vomiting" (page 497; Prasher 2005 ).[doi.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org]

  • Dubowitz Syndrome

    Neoplastic risk haematological malignancies and pancytopenia in 10%, childhood myelodysplasia in particular; lymphomas Inborn conditions appears to be normal or near to normal[atlasgeneticsoncology.org] Peripheral blood counts should be obtained in children with infectious illness or fatigue, as aplastic anemias have also been described [ 1, 2 ].[jmedicalcasereports.biomedcentral.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Seckel Syndrome

    2015-10-23 Optimal Levobupivacaine Concentration for Ultrasound-Guided Rectus Sheath Block in Pediatric Patients 猪股 伸一 第62回日本麻酔科学会総会/2015-5-28--2015-5-30 Measurements of fatigue[trios.tsukuba.ac.jp] The 12-yr-old female had pancytopenia, which is seen occasionally in patients with Seckel syndrome and is also a feature of Fanconi anemia, a well-recognized autosomal recessive[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Atelosteogenesis Type 2

    […] vision, see Arts syndrome ataxia-deafness-optic atrophy, lethal, see Arts syndrome ataxia-hypogonadism-choroidal dystrophy syndrome, see Boucher-Neuhäuser syndrome ataxia-pancytopenia[mygenomics.com] They include diffuse leg pain, fatigue, decline in physical function and, in children, a failure to walk despite otherwise normal development.[socialstyrelsen.se] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Familial Congenital Nasolacrimal Duct Obstruction

    In addition to the dysmorphic features, the boy had hypoglycemia and pancytopenia.[genome.jp] The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the[checkrare.com] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

  • Cutis Laxa

    During his early infancy, he had history of hospitalization for epistaxis, acute bronchopneumonia and pancytopenia.[ispub.com] This can lead to recurrent headaches, fatigue, and other irritations.[mccrackenmd.com] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br]

  • Weaver Syndrome

    Dec 15, 2011 0 0 Diseases, Conditions, Syndromes New IOM report identifies five symptoms to diagnose chronic fatigue syndrome Myalgic Encephalomyelitis/Chronic Fatigue Syndrome—commonly[medicalxpress.com] […] frequently in individuals with systemic juvenile idiopathic arthritis (SJIA) and in those with adult-onset Still disease. [1] Macrophage activation syndrome is characterized by pancytopenia[emedicine.medscape.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Mild Dysmorphic Features

    […] one self in the mirror, applying makeup, grooming and trying to alter one’s appearance, often with with cosmetic/plastic surgeries ( 3 ) Symptoms of depression, including fatigue[draxe.com] In addition, the two older males (ages 31 and 54) had microcephaly, short stature and pancytopenia, which was most severe in the 54-year-old man.[nature.com] , fourth, and fifth fingers; feet held in eversion, prominent heels; wide space between the first and second toes; proximally placed fifth toes; hypotonia; increased skin[ssmc-tl.com]

  • Baraitser Syndrome

    Lymphedema Bilateral camptodactyly Leukodystrophy Bipolar affective disorder Spina bifida Primary amenorrhea Hand polydactyly Ventricular hypertrophy Abnormal palate morphology Pancytopenia[mendelian.co] Children with these conditions may suffer chronic pain, injuries, fatigue and complex multi-systemic problems.[geneticdisordersuk.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Multiple Epiphyseal Dysplasia - Severe Proximal Femoral Dysplasia

    Patients present with a waddling gait, pain, fatigue and short stature. Contrary to Perthes disease, the abnormalities are usually symmetric.[radiologyassistant.nl] . • In the infantile type, pancytopenia, cranial nerve dysfunction, and mental retardation occur.[slideshare.net] (C) Adduction of the right forefoot with wide spacing between the first and second toes. The left foot shows only mild shortening of the first toe.[jmg.bmj.com]

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