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28 Possible Causes for Fatigue, Proximal Muscle Weakness of the Lower Extremity, Weakness after Climbing Stairs

  • Polymyalgia Rheumatica

    Associated symptoms include low-grade fever, malaise, fatigue, low mood, poor appetite, and weight loss.[ncbi.nlm.nih.gov] Fatigue and lack of appetite (possibly leading to weight loss) are also indicative of polymyalgia rheumatica. Anemia An overall feeling of illness or flu-like symptoms.[en.wikipedia.org] Other symptoms may include fever, weight loss, night sweats, depression, fatigue, and a general feeling of being ill.[arthritis.webmd.com]

  • Graves Disease

    Abstract A 46 year-old female patient presented to the hospital with ongoing and progressively increasing fatigue, severe nausea and vomiting, loss of appetite, constipation[ncbi.nlm.nih.gov] She suffered from thirst and fatigue for one month. Her serum calcium (a) levels were 19.0 mg/dL, and she was diagnosed with hypercalcemic crisis.[ncbi.nlm.nih.gov] CASE: A 33 year-old, 8-week pregnant woman with hypothyroidism, presents with a 2-week history of palpitations, sweating, nervousness and fatigue.[ncbi.nlm.nih.gov]

  • Polymyositis

    Muscle weakness versus fatigue It may be easy to confuse muscle weakness with the general feeling of tiredness and weariness caused by fatigue.[dmpmandyou.com] Symptoms include fatigue, difficulty speaking or swallowing, and muscle weakness that worsens over time.[muirortho.com] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 13, 2019[patientslikeme.com]

  • Cushing's Disease

    Some symptoms are Upper body obesity Thin arms and legs Severe fatigue and muscle weakness High blood pressure High blood sugar Easy bruising Lab tests can show if you have[fpnotebook.com] […] skin and stretch marks Irritability Easy bruising Excess hair growth (women) Depression Red, ruddy face Weak bones Extra fat around neck Acne Round face Balding (women) Fatigue[pituitarysociety.org] Signs and symptoms include a round face, upper body obesity, fragile and thin skin, purple stretch marks in the skin, fatigue, muscle weakness, hypertension, diabetes mellitus[fpnotebook.com]

  • Spinal Stenosis

    Symptoms: Leg (neurogenic Intermittent Claudication) Characteristics Leg Fatigue (dullness) or Leg Weakness Leg numbness or Paresthesia s (tingling sensation) Bilateral Leg[fpnotebook.com] Symptoms Lumbar spinal stenosis usually causes pain, numbness, tingling, and/or burning in one or both legs (buttocks, thighs, calves) and in many cases a feeling of fatigue[rothmaninstitute.com]

  • Limb-Girdle Muscular Dystrophy

    She began to experience proximal muscle weakness of both lower limbs without obvious inducement, which markedly increased when she climbed the stairs or stood up after squatting[ncbi.nlm.nih.gov] We review a series of different factors that may be connected in causing fatigue and atrophy, particularly considering the role of neuronal nitric oxide synthase (nNOS) and[ncbi.nlm.nih.gov] Muscular weakness was stable until the age of 21, afterward, progressive weakening of the muscles of the proximal regions of the lower extremities began.[frontiersin.org]

  • Muscular Dystrophy

    Symptoms may include: Fatigue Learning difficulties (the IQ can be below 75) Intellectual disability (possible, but does not get worse over time) Muscle weakness: Begins in[medlineplus.gov] Typically, proximal lower limb and truncal muscles are affected first, but eventually, there is progression to upper limb muscles and extremities 1,2.[radiopaedia.org] Pain and fatigue can be a significant factor, often under-appreciated, in limiting daily activities.[fshsociety.org]

  • Steroid Myopathy

    We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 12, 2019[patientslikeme.com] Patients often have weakness and an inability to perform activities such as rising from chairs, climbing stairs, or bringing their arms over their heads.[livestrong.com] In addition, steroid myopathy can occur, causing weakness primarily to proximal muscles of the upper and lower extremities and neck, which is frequently confused with progressive[medical-dictionary.thefreedictionary.com]

  • Lambert Eaton Myasthenic Syndrome

    An African 41 years-old SLE patient presented with persisting fatigue, myalgia and dyspnea, abolished reflexes and a bilateral ptosis.[ncbi.nlm.nih.gov] In contrast to myasthenia gravis, the weakness affects the legs more than the arms. This leads to difficulties climbing stairs and rising from a sitting position.[en.wikipedia.org] The most common initial complaint is proximal muscle weakness involving the lower extremities more than the upper extremities.[ncbi.nlm.nih.gov]

  • Dermatomyositis

    Running, climbing stairs, sitting from a lying position or standing from a seated position may become difficult.[arthritis.org] Muscle weakness versus fatigue It may be easy to confuse muscle weakness with the general feeling of tiredness and weariness caused by fatigue.[dmpmandyou.com] No weakness, fatigue, fevers or rashes anywhere else on his body. He works as a chiropractor and is concerned about his patients seeing his hands.[stanfordmedicine25.stanford.edu]

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