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33 Possible Causes for Fatigue, Quadriceps Muscle Weakness, Variable Hypoglycemia

  • Diabetes Mellitus Type 1

    There was no significant between-group difference in the number of severe hypoglycemia events. (p 0.1276).[ncbi.nlm.nih.gov] Patients experience the following: Increased thirst Increased hunger Increased urination Fatigue Blurry vision Rapid weight loss in a short amount of time Hunger Neurologic[symptoma.com] Increased appetite) Glycosuria (glucose in urine) Weight loss despite polyphagia Hyperglycemia (increased blood glucose) Ketonuria (ketones in urine) Fruity smelling breath Fatigue[physio-pedia.com]

  • Addison's Disease

    Abstract A 19-yr-old intact female variable flying fox ( Pteropus hypomelanus ) presented with lethargy, behavior changes, and substantial weight loss.[doi.org] Health Diseases Adrenal Fatigue Addison’s Disease and Adrenal Fatigue Adrenal insufficiency, also known as Addison’s disease, is an autoimmune condition.[dummies.com] Forty-eight per cent of patients showed abnormal fatigue, while 61% had severe fatigue. The CIS fatigue scores were significantly higher compared to controls (P 0·01).[ncbi.nlm.nih.gov]

  • Glycogen Storage Disease due to Glucose-6-Phosphat Transport Defect

    Association hypoglycemia, hyperglycemia, and glucose variability with morbidity and death in the pediatric intensive care unit. Pediatrics, 118(1), 173-179.[pedclerk.bsd.uchicago.edu] Most common cause of recurrent myoglobinuria Myoglobinuria occurs after moderate exercise or prolonged fasting Mitochondrial disorders Complex III, or I or IV Premature fatigue[neuromuscular.wustl.edu] […] but often after cessation of nighttime feedings or intercurrent illness Clinical features: Fasting hypoglycemia and ketosis, postprandial lactic acidosis Treatment: Frequent[msdmanuals.com]

  • Glycogen Storage Disease Type 2

    1 The variable clinical phenotype of three patients with hepatic glycogen synthase deficiency. ( 28245189 ) 2017 2 Pediatric patient with hyperketotic hypoglycemia diagnosed[malacards.org] Disorder or Manic Depression, Panic Disorder, schizophrenia, autism, head trauma, memory loss, low iq, mental retardation, learning disability, epilepsy, cancer, chronic fatigue[disability-claims.net] quadriceps muscle in 55% of patients only.[ojrd.com]

  • Secondary Myopathy

    Hypotension; hypoglycemia; bronzing of the skin Hyponatremia; hyperkalemia; ACTH assay; ACTH stimulation test Normal Myotonic discharges† Diminished glycogen content Glucocorticoid[aafp.org] The patient, who was wheel chair bound since two months, complained of backache, neck muscle weakness, and severe fatigue.[chanrejournals.com] weakness Pelvic girdle shoulder girdle muscles Arthralgias Inclusion body myositis Men Peak incidence: 50 yr Asymmetrical quadriceps muscle weakness and finger flexor muscle[clevelandclinicmeded.com]

  • Bilateral Leg Weakness

    Hypotension; hypoglycemia; bronzing of the skin Hyponatremia; hyperkalemia; ACTH assay; ACTH stimulation test Normal Myotonic discharges† Diminished glycogen content Glucocorticoid[aafp.org] Definite and early fatiguing. May have occasional arrests in movement. 3 Severely impaired.[books.google.de] L3 Decreased patellar reflex (knee jerk response) Sensation loss of the anterior thigh (front of one or both thighs) Weakness in quadriceps muscle (a large muscle group at[spineuniverse.com]

  • Glycogen Storage Disease Type 5

    1 The variable clinical phenotype of three patients with hepatic glycogen synthase deficiency. ( 28245189 ) 2017 2 Pediatric patient with hyperketotic hypoglycemia diagnosed[malacards.org] People with Glycogen Storage Disease type 5 appear physically healthy but suffer from fatigue post exercises.[symptoma.com] weakness Other Ptosis (23%): Normal EOM; May be asymmetric Bulbar (28%) Relatively spared: Quadriceps; Distal muscles Disease course: Progression 30 Slow, over years Severity[neuromuscular.wustl.edu]

  • Drug-induced Myopathy

    Hypotension; hypoglycemia; bronzing of the skin Hyponatremia; hyperkalemia; ACTH assay; ACTH stimulation test Normal Myotonic discharges† Diminished glycogen content Glucocorticoid[aafp.org] […] predinosolone avoid higher dose 40 mg/day and longer than 4 weeks use cause elevation of CPK- muscle damage clinical presenation (less severe) decreased/absent reflexes fatigue[quizlet.com] weakness Pelvic girdle shoulder girdle muscles Arthralgias Inclusion body myositis Men Peak incidence: 50 yr Asymmetrical quadriceps muscle weakness and finger flexor muscle[clevelandclinicmeded.com]

  • Myopathy, Endocrine

    Hypotension; hypoglycemia; bronzing of the skin Hyponatremia; hyperkalemia; ACTH assay; ACTH stimulation test Normal Myotonic discharges† Diminished glycogen content Glucocorticoid[aafp.org] Adrenal insufficiency produces generalized weakness, muscle cramping, and fatigue in 50 per cent of patients. Some patients also develop hyperkalemic paralysis.[ncbi.nlm.nih.gov] weakness Pelvic girdle shoulder girdle muscles Arthralgias Inclusion body myositis Men Peak incidence: 50 yr Asymmetrical quadriceps muscle weakness and finger flexor muscle[clevelandclinicmeded.com]

  • Glycogen Storage Disease due to Liver Phosphorylase Kinase Deficiency

    Fast-induced hypoglycemia and hyperlipidemia are variable and, if present, are generally mild. Adults are generally asymptomatic.[orpha.net] In the early morning the child may have low blood sugar which could cause: Paleness Vomiting Extreme fatigue Convulsions The children may also have a mild growth delay.[cancercarewny.com] weakness Other Ptosis (23%): Normal EOM; May be asymmetric Bulbar (28%) Relatively spared: Quadriceps; Distal muscles Disease course: Progression 30 Slow, over years Severity[neuromuscular.wustl.edu]

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