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16 Possible Causes for Fatigue, Short Stature in Children, Wide Space Between the First and Second Toe

  • Down Syndrome

    The most commonly reported side effects were "diarrhoea, fatigue, insomnia, nausea and vomiting" (page 497; Prasher 2005 ).[doi.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] Short stature as the major manifestation of celiac disease in older children. Clin Pediatr 1986; 25:13–6. 12. Rossi TM, Kumar V, Lerner A, et al.[journals.lww.com]

  • Multiple Endocrine Neoplasia Type 2B

    However, most people with endocrine disease complain of fatigue and weakness.[webmd.com] Figure 3 The first toe is longer than the others and there is a wide space between the first and second toe.[ijponline.biomedcentral.com] Children with MPS II grow steadily until about age 5, and then their growth slows and they develop short stature.[ghr.nlm.nih.gov]

  • Russell-Silver Syndrome

    We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 13, 2019[patientslikeme.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Russell-Silver syndrome (RSS) is characterized by slow growth both in utero and after birth, short stature, and specific facial features.[gemssforschools.org]

  • Seckel Syndrome

    2015-10-23 Optimal Levobupivacaine Concentration for Ultrasound-Guided Rectus Sheath Block in Pediatric Patients 猪股 伸一 第62回日本麻酔科学会総会/2015-5-28--2015-5-30 Measurements of fatigue[trios.tsukuba.ac.jp] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] One child had classical Seckel syndrome, a sib pair had the features of the syndrome with less severe short stature, and in two children the diagnosis was not confirmed.[ncbi.nlm.nih.gov]

  • Dubowitz Syndrome

    Peripheral blood counts should be obtained in children with infectious illness or fatigue, as aplastic anemias have also been described [ 1, 2 ].[jmedicalcasereports.biomedcentral.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] More about psychosocial adaptation to short stature can be learned from parents of short children and from your growth clinic doctor, nurse and psychologist.[web.archive.org]

  • Atelosteogenesis Type 2

    They include diffuse leg pain, fatigue, decline in physical function and, in children, a failure to walk despite otherwise normal development.[socialstyrelsen.se] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] A constitutional short stature in children is not considered as a short stature or dwarfism as the condition happens temporarily and the child will resume normal growth eventually[epainassist.com]

  • Short Stature due to Endocrine Disorder

    Other signs and symptoms may include: Deepened, husky voice Enlarged organs (liver, heart, kidneys, and spleen) Enlarged tongue Erectile dysfunction Fatigue Headaches and[labtestsonline.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] short stature.[karger.com]

  • Familial Congenital Nasolacrimal Duct Obstruction

    The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the[checkrare.com] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] Haghi et al. (2004) studied 9 children with Jacobsen syndrome, 8 of whom had short stature.[genome.jp]

  • Greenberg Dysplasia

    Clinical Features Clinical features are often nonspecific and are generally related to the corresponding cytopenia (ie, bleeding associated with thrombocytopenia; fatigue[emedicine.medscape.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The condition affects children and teens, although they have no other physical abnormality except short stature.[illnessopedia.org]

  • Kenny-Caffey Syndrome Type 1

    The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the[checkrare.com] space between the first and second toes.[medcraveonline.com] These may enable better targeting of GH treatment in children with short stature.[ijpeonline.biomedcentral.com]

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