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578 Possible Causes for Fatigue, Sore Mouth, T Cell Activation Increased

  • Hypersensitivity

    However, increased activation of CD4 T-cell and CD8 T-cells was only observed following four days of DDAB exposure.[ncbi.nlm.nih.gov] These sores can be found on the genitals, vagina, anus, rectum, lips and mouth. Pregnant women can transmit the disease to their unborn child.[niaid.nih.gov] These reactions often cause chronic joint or muscle pain, inflammation, and swelling, leading to generalized fatigue and lack of energy.[medbroadcast.com]

  • Food Allergy

    Memory T cells are increased in frequency and have distinct activation requirements and cell-surface proteins that distinguish them from armed effector T cells 10-25.[ncbi.nlm.nih.gov] […] defects of permanent teeth Adults are less likely to have digestive signs and symptoms and may instead have one or more of the following: anemia bone or joint pain canker sores[web.archive.org] While not life-threatening, symptoms can be severe and range from gastrointestinal distress, headache and chronic fatigue.[enjoylifefoods.com]

  • Celiac Disease

    APC presents the toxic peptide to CD4 T cells. Activated gluten-reactive CD4 T-cells produce high levels of pro-inflammatory cytokines.[doi.org] […] problems such a canker sores or dry mouth seizures tingling numbness in the hands and feet tiredness weak and brittle bones Adults who have digestive symptoms with celiac[web.archive.org] Bilateral non traumatic femoral neck fatigue fracture is a rare condition usually occurring secondary to medical conditions such as pregnancy, pelvic irradiation, corticosteroid[ncbi.nlm.nih.gov]

  • Sjögren Syndrome

    Human exposure to an extremely high dose of TCDD in vivo induced a selective increase in the frequency of T cells producing IL-22 but not IL-17, IL-10, or IFN-γ ( 69 ).[doi.org] Other symptoms may include: Contact lens discomfort Dry sinuses and frequent sinus infections or nosebleeds Sore mouth, tongue or throat Difficulty chewing or swallowing Dry[allaboutvision.com] […] with fatigue.[ncbi.nlm.nih.gov]

  • Systemic Scleroderma

    Levels of IL-4 are elevated in the sera of patients with SSc ( 83 ), and the number of IL-4–producing T cells is increased in their peripheral blood ( 84, 85 ).[jci.org] 0200042 Telangiectasia of the skin 0100585 Xerostomia Dry mouth Dry mouth syndrome Reduced salivation [ more ] 0000217 5%-29% of people have these symptoms Abnormal bowel[rarediseases.info.nih.gov] The severity of the scleroderma patient fatigue is not on the same level as a ‘healthy’ person would feel fatigue.[sclerodermanews.com]

  • Erythema Multiforme

    In contrast to the enhanced immune activity, thalidomide also increased the levels of FoxP3 /CD4 /CD25 Treg cells, which are a subset of immunoregulatory T-cells.[scielo.br] sores Vision problems There are two forms of EM: EM minor usually involves the skin and sometimes mouth sores.[nlm.nih.gov] Adverse effects, observed in 4 patients, included fatigue, macrocytic anemia, anxiety, insomnia and involuntary movements, and drug-induced lupus erythematosus.[ncbi.nlm.nih.gov]

  • Malabsorption Syndrome

    […] in the intestinal permeability.  One such peptide is a 33-amino acid sequence, which is a potent activator of specific T-cell lines from patients with CD. 41.  The subsequent[slideshare.net] […] of the mouth), and anemia.[iffgd.org] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 12, 2019[patientslikeme.com]

  • Behçet Disease

    Different ethnic populations show increased T- and B-cell responses to these proteins and hence HSPs may be pathophysiologically related to the development of Behcet’s syndrome[symptoma.com] , Mouth Sores, Behcets, Behcet Type: Phase 3 Drug Trial Target: 204 Participants Study Info Study Locations Sending Send SMS with Study Info: SMS Sent![studypages.com] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 13, 2019[patientslikeme.com]

  • Stevens-Johnson Syndrome

    […] normal T-cell expressed and secreted (RANTES), IL-7, IL-12p70 and IL-13, with maximal increase in GM-CSF and maximal downregulation of IP-10, respectively.[ncbi.nlm.nih.gov] The initial signs of SJS are bloody crusts on the lips, a sore mouth that has a foul smell, and purple-red tender spots on the skin.[childrensclinicofraceland.com] Novel physical sequelae included chronic fatigue (76%) and pruritus (53%).[ncbi.nlm.nih.gov]

  • HIV Infection

    […] the vaginas of mice increased numbers of the activated CD4 T cells that are the virus’s primary target, establishing a direct link between the high-risk bacteria and a known[ragoninstitute.org] ulcers.[health24.com] Fatigue can be both an early and later sign of HIV.[health.com]

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