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157 Possible Causes for Favism, Splenomegaly

  • Autoimmune Hemolytic Anemia

    Examination demonstrated scleral icterus, splenomegaly, and anemia. By peripheral blood smear, the patient was diagnosed with Plasmodium ovale.[ncbi.nlm.nih.gov] She was found to have splenomegaly, generalized lymphadenopathy, pancytopenia, and acute hepatic failure.[ncbi.nlm.nih.gov] […] fever (65% vs 26%, p   0.001), weight loss   2 kg (39% vs 6%, p   0.001), reticuloendothelial manifestations (48% vs 8%, p   0.001), hepatomegaly (25% vs 2%, p   0.001) and splenomegaly[ncbi.nlm.nih.gov]

  • Hypervitaminosis A

    Further systemic consequences of HA are hepatotoxicity, hepatomegaly, splenomegaly, ascites, migratory arthritis, and hepatic hydrothorax.[symptoma.com] […] compounds concentrations consumed consumption coumestrol deficiency dietary diets containing disease doses enterotoxin enzyme excretion experimental extracts factor fatty acids favism[books.google.com] Splenomegaly. Raised intracranial pressure. Stupor. Limited body movement. Cirrhosis of liver.[nhp.gov.in]

  • Hemolytic Anemia

    […] suffer from a mild hemolytic anemia (Hb levels ranging from 10 to 12.7g/mL) associated with macrocytosis, reticulocytosis, hyperbilirubinemia, hyperferritinemia and slight splenomegaly[ncbi.nlm.nih.gov] However, the commonest trigger is fava beans (Vicia faba) ingestion, causing AHA (favism), which may be life-threatening especially in children.[ncbi.nlm.nih.gov] Severe disease may cause jaundice or abdominal discomfort and fullness due to splenomegaly (an enlarged spleen).[merckmanuals.com]

  • Congenital Hemolytic Anemia

    Children with massive splenomegaly had similar outcomes compared with children without massive splenomegaly.[ncbi.nlm.nih.gov] […] usually excluding hemoglobin abnormalities as well, but rather encompassing defects of glycolysis in the erythrocyte. [2] Glucose-6-phosphate dehydrogenase deficiency (G6PD or favism[en.wikipedia.org] […] excluding hemoglobin abdormalities as well, but rather encompassing defects of glycolysis in the erythrocyte. [ 2 ] Glucose-6-phosphate dehydrogenase deficiency (G6PD or favism[en.academic.ru]

  • Hexokinase Deficiency

    Jaundice, splenomegaly, pallor and constitutional symptoms such as lethargy and fatigue are main symptoms.[symptoma.com] Glutathione reductase deficiency is an autosomal recessive disorder and associated with drug-sensitive hemolytic anemia and favism.[umcutrecht.nl] Cholecystitis ; Cholelithiasis ; Congenital onset ; Hyperbilirubinemia ; Jaundice ; Nonspherocytic hemolytic anemia ; Normochromic anemia ; Normocytic anemia ; Reticulocytosis ; Splenomegaly[mousephenotype.org]

  • Cholelithiasis

    A nine year old mentally retarded girl with moderate splenomegaly and ascites presented with chronic cholelithiasis.[ncbi.nlm.nih.gov] Epidemiological data on the frequency of G6PD deficiency in normal males of Northern Sardinian origin were derived from the screening campaign for the prevention of favism[g6pd.org] In cirrhosis , portal hypertension leads to splenomegaly . This, in turn, causes red cell sequestration, leading to a modest increase in hemoglobin turnover.[emedicine.medscape.com]

  • Favism

    Abdominal ultrasound may be used to detect gallstones and/or splenomegaly. Coombs' test is negative.[patient.info] Favism is most commonly diagnosed in children between 1-5 years of age with G6PD, while cases of favism in adults have been infrequently reported.[symptoma.com] 11 , 12 G6PD deficiency is one of a group of congenital hemolytic anemias, and its diagnosis should be considered in children with a family history of jaundice, anemia, splenomegaly[aafp.org]

  • Methemoglobinemia

    D73.3 Abscess of spleen D73.5 Infarction of spleen D73.8 Other diseases of spleen D73.81 Neutropenic splenomegaly D73.89 Other diseases of spleen D73.9 Disease of spleen,[icd10data.com] The latter is known as favism [ 5 ]. Favism is characterized by acute hemolysis, hemoglobinuria, anemia, and jaundice.[link.springer.com] 2019 Billable/Specific Code congenital D74.0 enzymatic D74.0 (congenital) Hb M disease D74.0 hereditary D74.0 ICD-10-CM Codes Adjacent To D74.0 D73.2 Chronic congestive splenomegaly[icd10data.com]

  • Vinblastine

    An HIV-positive man from Somalia presented with severe malaise, weight loss, relapsing fever, lymphadenopathy and splenomegaly.[ncbi.nlm.nih.gov] Some people suffer from a genetic problem called favism and can't eat fava beans.[healdove.com]

  • Zellweger Syndrome

    Systemic Features: Many infants have hepatomegaly at birth and may develop splenomegaly as well. Jaundice often occurs with intrahepatic biliary dysgenesis.[disorders.eyes.arizona.edu] Three well-known inherited diseases confer resistance to malaria: sickle-cell anemia (HBB), thallasemia (HBB), and Favism or G6PD deficiency (G6PD).[openhumangenome.com] Please see the OMIM entry for G6PD for more information about favism. 10. Christopher Naugler (2008) Hemochromatosis: A Neolithic adaptation to cereal grain diets.[openhumangenome.com]

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