Ferritin Increased: Causes & Reasons

Possible Causes for Ferritin Increased

That’s why, ferritin is increased. (Stores are there, but unavailable!) What is hepcidin? [medicowesome.com]

Disordered iron metabolism as manifested by a low serum iron, decreased serum transferrin, decreased transferrin saturation, increased serum ferritin, increased reticuloendothelial [ncbi.nlm.nih.gov]

Serum Iron : decreased TIBC: decreased [because this is inverse of ferritin] ferritin [stored] : INCREASE transferring saturation: decrease Free erythrocyte protoporphoryin [usmleforum.com]

Hypochromic Microcytic Anemia with Iron Overload Type 2

Congenital sideroblastic anemia is caused by one of numerous X-linked or autosomal mutations and is usually a microcytic-hypochromic anemia with increased serum iron and ferritin [merckmanuals.com]

Affiliated tissues include bone, bone marrow and pituitary, and related phenotypes are anemia and increased serum ferritin [malacards.org]

Serum iron, percentage saturation and ferritin are increased. The total iron-binding capacity of the cells is normal to decreased. [ipfs.io]

Hemochromatosis

Increased serum ferritin levels may also be caused by inflammation. [arupconsult.com]

The correlation between uricemia and log(ferritin) with partial regression correlation coefficients was 0.307 (P CONCLUSIONS: The increase in uricemia is associated with the [ncbi.nlm.nih.gov]

Case 1: A 12 year-old male from Central Italy with beta-thalassemia trait, increased aminotransferases, ferritin 9035 ng/ml and transferrin saturation 84%, massive hepatocellular [ncbi.nlm.nih.gov]

Hemochromatosis-Related Cardiomyopathy

ferritin and increased transferrin saturation. [patient.info]

[…] caused by hereditary hemochromatosis; increased serum ferritin levels ( > 1000 μg/L ) Histology Color stain: Prussian blue Pronounced siderosis in iron staining with iron [amboss.com]

Biochemical abnormalities include elevated serum iron, transferrin saturation and ferritin. [orpha.net]

Sideroblastic Anemia

There should be an increase in ferritin. Pathoma and RR both state this and even FA shows an increase in ferritin (look at page 381 Pholston). [forums.studentdoctor.net]

[…] iron), total iron binding capacity (TIBC) normal or decreased (due to increased ferritin and iron). [stepwards.com]

Serum iron, ferritin, and transferrin are typically increased. Treat the underlying disorder and consider pyridoxine in congenital cases. [merckmanuals.com]

Anemia due to Infection

Serum iron and percentage saturation of transferrin decreased, whereas serum ferritin increased significantly. [pediatrics.aappublications.org]

A good response is likely if, after 2 wk of therapy, Hb has increased > 0.5 g/dL and serum ferritin is 400 ng/mL. [merckmanuals.com]

Apart from the prolonged acute phase response, the inverse relation between ferritin and CD4 cell count may also be caused by increased oxidative stress [ 38 ] related to [bmcinfectdis.biomedcentral.com]

Adult-Onset Still Disease

The elevated ferritin may reflect increased synthesis of ferritin by hepatocytes as acute phase reactants. [stillsdisease.org]

Multivariate analysis showed that a low erythrocyte sedimentation rate, a low albumin level, an increase in ferritin of over 2 folds, and the development of MAS on admission [ncbi.nlm.nih.gov]

Subsequently, the serum level of ferritin decreased, but serum total bilirubin increased to 17.3 mg/dL. Therefore, cyclosporin was administered orally. [ncbi.nlm.nih.gov]

Autosomal-Recessive Pyridoxine-Refractory Sideroblastic Anemia

[…] serum ferritin Elevated serum ferritin High ferritin level Increased ferritin Increased serum ferritin level [ more ] 0003281 Infantile onset Onset in first year of life [rarediseases.info.nih.gov]

Serum iron, percentage saturation and ferritin are increased. The total iron-binding capacity of the cells is normal to decreased. [scientiait.com]

Percent of people who have these symptoms is not available through HPO Autosomal recessive inheritance 0000007 Decreased mean corpuscular volume 0025066 Hypochromia 0032231 Increased [rarediseases.info.nih.gov]

Primary Hemochromatosis Type 1

The amount of ferritin increases if the levels of iron in the blood increase. [yourgenome.org]

[…] serum ferritin Elevated serum ferritin High ferritin level Increased ferritin Increased serum ferritin level [ more ] 0003281 Increased serum iron 0003452 Osteoporosis 0000939 [rarediseases.info.nih.gov]

ferritin levels and increased transferrin saturation DD: primary or secondary hemochromatosis (e.g., patients with chronic viral hepatitis or toxic liver disease) Persons [mgz-muenchen.de]

Aceruloplasminemia

[…] iron concentration in liver 0012465 Increased serum ferritin Elevated serum ferritin High ferritin level Increased ferritin Increased serum ferritin level [ more ] 0003281 [rarediseases.info.nih.gov]

and increased iron in the glia, neurones, basal ganglia and dentate nucleus, liver cells, and pancreatic islets. [medical-dictionary.thefreedictionary.com]

Showing of 28 | 80%-99% of people have these symptoms Chorea 0002072 Decreased serum ceruloplasmin 0010837 Diabetes mellitus 0000819 Elevated hepatic iron concentration Increased [rarediseases.info.nih.gov]

Hemophagocytic Lymphohistiocytosis

LDL cholesterol [ more ] 0003141 Increased serum ferritin Elevated serum ferritin High ferritin level Increased ferritin Increased serum ferritin level [ more ] 0003281 Increased [rarediseases.info.nih.gov]

ferritin, hemophagocytosis in bone marrow, decreased NK cell cytotoxicity and increased soluble CD25 [1]. [indianpediatrics.net]

IL-1 is known to increase the synthesis of ferritin subunits in vitro [ 7 ]. [ped-rheum.biomedcentral.com]

Porphyria Cutanea Tarda

Viral hepatitis studies If a blood ferritin shows iron stores are increased, further investigations may include transferrin saturation and genotyping for hereditary haemochromatosis [dermnetnz.org]

Early effects of chloroquine treatment As is evident from Table II, the treatment was followed by a marked increase in serum ALAT, ferritin and urinary porphyrins. [medicaljournals.se]

Fasting blood sugar because of the increased incidence of diabetes. Antinuclear antibodies because of the increased incidence of lupus erythematosus. [dermnetnz.org]

Thalassemia

Insulin resistance and serum ferritin showed significant increase at 6 months (P CONCLUSIONS: Prolonged disease duration and higher serum ferritin adversely affects glucose [ncbi.nlm.nih.gov]

As Survival Increases in Beta Thalassemia, Renal Complications Emerge Renal complications occur in more than half of patients with beta thalassemia, but research on their [hematologyadvisor.com]

Serum bilirubin, iron, and ferritin levels are increased. [merckmanuals.com]

Childhood Hodgkin Lymphoma

Hypoalbuminemia, as well as increased acute-phase reactants (C-reactive protein, erythrocyte sedimentation rate, ferritin, and copper), are other usual findings. [symptoma.com]

Paroxysmal Nocturnal Hemoglobinuria

Deteriorating kidney function and persistent Fanconi syndrome were accompanied by a progressive increase in serum ferritin levels. [ncbi.nlm.nih.gov]

Pernicious Anemia

[…] in mean corpuscular volume and levels of ferritin and gastrin, and a decrease in vitamin B 12 levels. [doi.org]

Increased gastrinemia and low seric pepsinogen were also found. [elsevier.es]

Stratification by age cohorts (< 20 years to > 60 years) of ABG patients identified by hypergastrinemia and positive parietal cell antibodies has shown a regular and progressive increase [doi.org]

Gaucher Disease

Reduced TSAT (4%) with mildly increased ferritin levels suggested that microcytic anaemia was partially related to iron deficiency. Haemolytic indices were normal. [touchoncology.com]

Decreased hepatic glucocerebroside Decreased plasma glucocerebroside Increase in signal intensity in MRI of bone marrow U.S. [physio-pedia.com]

ferritin (352 ng/ml). [touchoncology.com]

Uremic Anemia

The serum ferritin level should be greater than 100 mcg/mL. [medscape.com]

As expected, hematocrit and hemoglobin increased after intravenous iron and α-darbepoetin treatments. [jasn.asnjournals.org]

This was unlikely because serum ferritin when checked were elevated in these patients. [kjim.org]

CIMDAG Syndrome

(F) / LIC 1 de novo c.850A>T (p.Arg284Trp) heterozygous 6 y.o., F, European- and Hispanic-American 7.3 (increased irritability when anemia worsens) 380–500 89–98 F 840, LIC [ncbi.nlm.nih.gov]

VPS4A (NM_013245.2) Mutations Age, Sex, & Ethnic Background Laboratory Findings Age at First Transfusion Transfusion Requirement Non-hematologic findings Lowest Hb ARC MCV Ferritin [ncbi.nlm.nih.gov]

Histoplasmosis

[…] dehydrogenase levels, and increased ferritin expression, none of which are specific for disseminated histoplasmosis but all of which are highly suggestive of this diagnosis [doi.org]

[…] level, and increased serum ferritin level may provide clues to the diagnosis. [doi.org]

Laboratory studies reveal elevated alkaline phosphatase levels, pancytopenia, an increased Westergren sedimentation rate, elevated C-reactive protein levels, high lactate [doi.org]

COVID-19

Education Coronavirus disease... Coronavirus disease 2019 (covid-19): a guide for UK GPs Mohammad S Razai, academic clinical fellow in primary care1, Katja Doerholt, consultant in infectious diseases2, Shamez Ladhani, consultant in infectious diseases and public health3, Pippa Oakeshott, professor of general practice1[…] [bmj.com]

Gaucher Disease Type 1

Hepcidin was discrepantly low in relation to ferritin levels. [ncbi.nlm.nih.gov]

Reduced TSAT (4%) with mildly increased ferritin levels suggested that microcytic anaemia was partially related to iron deficiency. Haemolytic indices were normal. [touchoncology.com]

[…] converting enzyme, ferritin and tartrate-resistant acid phosphatases. [orpha.net]

Neonatal Hemochromatosis

Increase in glycosylated and nonglycosylated serum ferritin in chronic alcoholism and their evolution during alcohol withdrawal. [medicinaylaboratorio.com]

The beneficial effect of acute phase increase in serum ferritin. Eur J Intern Med 2016;35:e16-e17. https://doi.org/10.1016/j.ejim.2016.07.020 Srai SK, Sharp P. [medicinaylaboratorio.com]

Chronic Alcoholism

Of five chronic alcoholics with acute skeletal muscle necrosis (rhabdomyolysis) three developed acute heart failure with disturbances of rhythm and conduction. Symptoms came on abruptly after a period of intensified drinking. Myocardial infarction, thiamine deficiency, and cobalt intoxication were excluded. Probably[…] [ncbi.nlm.nih.gov]

Hyperthyroidism

What Is Hyperthyroidism? Hyperthyroidism is a medical condition that results from an excess of thyroid hormone in the blood. Thyroid hormones control most metabolic processes in the body. In cases of hyperthyroidism, these processes are often sped up causing symptoms of hyperthyroidism, which will be discussed[…] [onhealth.com]

Diabetes Mellitus Type 1

Type 1 diabetes is an autoimmune disease that gradually destructs insulin-producing beta cells. Over the years, clinicians' knowledge regarding the immunopathogenesis of this disease has greatly increased. Immunotherapies that can change the course of immune-mediated destruction and preserve and possibly regenerate[…] [ncbi.nlm.nih.gov]

Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily involves the joints. RA causes damage mediated by cytokines, chemokines, and metalloproteases. Characteristically, peripheral joints (eg, wrists, metacarpophalangeal joints) are symmetrically inflamed, leading to progressive destruction of[…] [merckmanuals.com]

Bronchogenic Carcinoma

We report a case of localized fibrous mesothelioma (LFM) of the pleura with bronchogenic carcinoma. LFM arose in the visceral pleura of the upper lobe in the left lung, and lung adenocarcinoma was located in the ipsilateral lower lobe. LFM is a rare mesenchymal tumor of the pleura. Concomitant occurrence with[…] [ncbi.nlm.nih.gov]

Eating Disorder

Eating disorders are abnormal eating habits that can threaten your health or even your life. They include: Anorexia nervosa : Individuals believe they’re fat even when they’re dangerously thin and restrict their eating to the point of starvation. Bulimia nervosa : Individuals eat excessive amounts of food, then[…] [apa.org]

Viral Hepatitis

Abstract The commonest causes of acute pancreatitis are cholelithiasis and alcohol. Rare causes include various viral infections, among which mumps is the commonest. Hepatitis A, hepatitis B and, recently, hepatitis E have been reported to cause acute but mild pancreatitis in patients with acute viral hepatitis. This[…] [ncbi.nlm.nih.gov]