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516 Possible Causes for Fetus Small for Gestational Age, Single Transverse Palmar Crease, Wide Space Between the First and Second Toe

  • Seckel Syndrome

    transverse palmar crease 0000954 Sloping forehead Inclined forehead Receding forehead [ more ] 0000340 Small anterior fontanelle 0000237 Small for gestational age Birth weight[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Down Syndrome

    transverse palmar crease, and short fifth finger with clinodactyly.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org] transverse palmar creases ( 60% of patients) Joint hyperextensibility or hyperflexibility Neuromuscular hypotonia Diastasis recti Dry skin Premature aging Congenital heart[emedicine.medscape.com]

    Missing: Fetus Small for Gestational Age
  • Kenny-Caffey Syndrome Type 1

    transverse palmar crease, and wide space between the first and second toes.[medcraveonline.com] space between the first and second toes.[medcraveonline.com] Upward slanted palpebral fissures, single transverse palmar creases, wide gap between the first and second toes, and hypotonia are strongly suggesting the possibility of Down[medcraveonline.com]

  • Ring Chromosome 10

    Their common features were mental and growth retardation, low birth weight, microcephaly, stubby nose, hypertelorism, strabismus, wide set nipples, single transverse palmar[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The main features are low birth weight, microcephaly, stubby nose with a prominent nasal bridge, hypertelorism, strabismus, wide-set nipples, single transverse palmar creases[malacards.org]

    Missing: Fetus Small for Gestational Age
  • Russell-Silver Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov] ] 0001256 Obesity Having too much body fat 0001513 Postnatal microcephaly 0005484 Precocious puberty Early onset of puberty Early puberty [ more ] 0000826 Sandal gap Gap between[rarediseases.info.nih.gov]

    Missing: Single Transverse Palmar Crease
  • Congenital Malformation

    Be able to distinguish major anomalies (such as cleft palate, congenital cardiac defects) from minor anomalies (single transverse palmar crease) It is important to specifically[med.umich.edu]

    Missing: Wide Space Between the First and Second Toe
  • Insulin-Like Growth Factor Type 1 Deficiency

    transverse palmar crease 0000954 Truncal obesity 0001956 Percent of people who have these symptoms is not available through HPO Abnormality of metabolism/homeostasis Laboratory[rarediseases.info.nih.gov] […] delay 0001270 Myopia Close sighted Near sighted Near sightedness Nearsightedness [ more ] 0000545 Prominent forehead Pronounced forehead Protruding forehead [ more ] 0011220 Single[rarediseases.info.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Atelosteogenesis Type 2

    transverse palmar creases.[documents.tips] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] “Mongoloid” facies; simian (Latin simia : “ape”) crease (single transverse palmar); hypotonia; ligamentous laxity; instability of C1-C2 [A], hips [B], and patella; flat feet[musculoskeletalkey.com]

    Missing: Fetus Small for Gestational Age
  • Aarskog-Scott Syndrome

    transverse palmar crease 0000954 Strabismus Cross-eyed Squint Squint eyes [ more ] 0000486 Talipes 0001883 1%-4% of people have these symptoms Broad philtrum 0000289 Global[rarediseases.info.nih.gov] Sporadic Symptoms Round face and a shorter neck, epicanthic folds, maxillary hypoplasia, which causes several facial abnormalities, and single transverse palmar crease may[news-medical.net] […] planus Flat feet Flat foot [ more ] 0001763 Round face Circular face Round facial appearance Round facial shape [ more ] 0000311 Short neck Decreased length of neck 0000470 Single[rarediseases.info.nih.gov]

    Missing: Fetus Small for Gestational Age Wide Space Between the First and Second Toe
  • Postaxial Oligodactyly, Tetramelic

    transverse palmar crease 32 HP:0000954 9 radial bowing 32 HP:0002986 10 postaxial oligodactyly 32 HP:0006210 11 partial-complete absence of 5th phalanges 32 HP:0006209 12[malacards.org] transverse palmar crease Symptoms // Phenotype % cases Autosomal recessive inheritance Uncommon - Between 30% and 50% cases Bilateral single transverse palmar creases Uncommon[mendelian.co] transverse palmar crease Radial deviation of finger Broad hallux Cleft upper lip Gastrointestinal dysmotility Postnatal macrocephaly Microtia, first degree Branchial fistula[mendelian.co]

    Missing: Fetus Small for Gestational Age Wide Space Between the First and Second Toe