Create issue ticket

552 Possible Causes for Fever, Hepatomegaly, Lactate Dehydrogenase Increased

  • Infectious Mononucleosis

    The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus[ncbi.nlm.nih.gov] You don't usually get glandular fever more than once.[nhs.uk] Although the complaints at admission did not differ between these two patient groups, the incidence of clinical signs (tonsillopharyngitis, lymphadenopathy, hepatomegaly,[ncbi.nlm.nih.gov]

  • Reye Syndrome

    Serum glutamic oxaloacetic transaminase and lactate dehydrogenase (LDH) values increased strikingly on the third day after the onset of coma.[ncbi.nlm.nih.gov] A 2-year-old boy had acute fever, malaise, and somnolence with hepatomegaly, increased blood ammonia content (338 microM), high SGOT, low blood glucose content, and mild acidosis[ncbi.nlm.nih.gov] Here we describe a case of Reye syndrome diagnosed at postmortem liver biopsy of a three-year old girl who presented with vomiting, low grade fever for three days and loss[ncbi.nlm.nih.gov]

  • Acute Lymphoblastic Leukemia

    Serum level of lactate dehydrogenase (LDH) predicts increased anaerobic glycolysis and is associated with metabolic modulation in cancer cells.[ncbi.nlm.nih.gov] Bone pain/tenderness, hepatomegaly, and splenomegaly may be present. About 7% of children have CNS involvement at the time of diagnosis.[lecturio.com] We present the case of a 10-year-old boy with acute lymphoblastic leukemia who developed a diffuse, morbilliform eruption in the setting of fever and pancytopenia.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    The effect of eculizumab on intravascular hemolysis was demonstrated by a reduction in lactate dehydrogenase levels at all measurements after baseline.[ncbi.nlm.nih.gov] […] characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly[medical-dictionary.thefreedictionary.com] Thromboses, as observed in our case, may be associated with fever and marked inflammation.[ncbi.nlm.nih.gov]

  • Malaria

    Patients with heavy hepatocyte load may present with hepatomegaly.[symptoma.com] Fever was not reported with this patient.[ncbi.nlm.nih.gov] Enlargement of the liver (hepatomegaly) and spleen (splenomegaly) may be found during a physical examination.[betterhealth.vic.gov.au]

  • Rocky Mountain Spotted Fever

    Hepatomegaly may be present, but jaundice is infrequent. Nausea and vomiting are common. Localized pneumonitis may occur.[msdmanuals.com] Rocky Mountain spotted fever and Mediterranean spotted fever are rickettsial infections primarily of endothelial cells that normally have a potent anticoagulant function.[ncbi.nlm.nih.gov] Her heart and lungs sound fine, her abdomen is nonacute and there is no evidence of hepatomegaly. No rash or petechiae are found.[acphospitalist.org]

  • Primary Myelofibrosis

    The latter was associated more frequently with anaemia, thrombocytopenia, peripheral blood blasts and increased lactate dehydrogenase levels.[ncbi.nlm.nih.gov] The patient, a 62-year-old female, having had primary myelofibrosis for 13 years and a splenectomy 4 years before, was admitted because of high fever, hepatomegaly, thrombocythemia[ncbi.nlm.nih.gov] Although ruxolitinib rapidly induced relief, he developed a high-grade fever. A comprehensive fever work-up found no apparent cause of the fever, except for PMF.[ncbi.nlm.nih.gov]

  • Liver Abscess

    We report a case of a 63-year-old male with a history of anorexia for 3 weeks, fever for 4 days and examination findings of tender hepatomegaly with a liver span of 15 cm[ncbi.nlm.nih.gov] We report a case of a previously healthy female patient who initially presented with fever, jaundice and right upper quadrant pain three days after dilatation and stenting[ncbi.nlm.nih.gov] The main clinical features were fever (100%), right hypochodric pain (100%), tender hepatomegaly (90%) and intercostal tenderness (60%).[ncbi.nlm.nih.gov]

  • Amebic Liver Abscess

    Most (81%) patients had hepatomegaly on physical examination and some had a well-defined mass.[ncbi.nlm.nih.gov] Common clinical symptoms were fever (93%) and abdominal pain (93%). Common signs were right upper quadrant tenderness (60%), hepatomegaly (67%).[ncbi.nlm.nih.gov] In travelers with fever, abdominal pain, and hepatomegaly amebic liver abscess must be considered. Medical treatment with metronidazole is effective in more than 90%.[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    Additional autopsy findings included cardiomegaly with a heart weight of 450 gm (312 78), right atrial and right ventricular chamber dilatation, and hepatomegaly with a liver[ncbi.nlm.nih.gov] Urgent medical evaluation is recommended for patients with sickle cell disease (SCD) and fever.[ncbi.nlm.nih.gov] Children with SCD presenting to the ED with fever and shortness of breath, tachypnea, cough, rales, or chest pain should receive a CXR due to high ACS rates.[ncbi.nlm.nih.gov]

Similar symptoms