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2,819 Possible Causes for Fever, Hepatomegaly, Lymphadenopathy, Pancytopenia

  • Malignant Neoplasm

    To date, phenytoin-induced nasopharyngeal lymphadenopathy has not previously been reported in the literature.[ncbi.nlm.nih.gov] After 15 months a diagnosis of urothelial carcinoma of the bladder was made; after a further 6 months pneumonitis and pancytopenia developed.[ncbi.nlm.nih.gov] Symptoms may include pain on one side of the back, blood in the urine, high blood pressure, and fever.[ugr.es] She was discharged one month later in poor condition with the principal diagnosis of hemorrhage/ pancytopenia, and a secondary diagnosis of metastatic head and neck cancer[ncbi.nlm.nih.gov]

  • Chronic Lymphocytic Leukemia

    Lymphadenopathy may or may not be present. Stage III: Absolute lymphocytosis with anemia is present. Hepatosplenomegaly and lymphadenopathy may or may not be present.[symptoma.com] […] of the left zygomatic region; anterior nasal bleeding; pustulous non-itching lesions at the cervical region and posterior thorax; enlarged bilateral axillary lymph nodes; hepatomegaly[ncbi.nlm.nih.gov] The symptoms of this infection range from a silent infection to fever, enlargement of the liver and spleen, weight loss, and pancytopenia.[ncbi.nlm.nih.gov] Brentuximab vedotin had a transient effect, but the patient died of sepsis due to residual PTCL and pancytopenia.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] The patient, a 62-year-old female, having had primary myelofibrosis for 13 years and a splenectomy 4 years before, was admitted because of high fever, hepatomegaly, thrombocythemia[ncbi.nlm.nih.gov] Primary myelofibrosis is a unique entity among BCR-ABL-negative myeloproliferative diseases, manifesting as bone marrow fibrosis and pancytopenia.[ncbi.nlm.nih.gov] Although ruxolitinib rapidly induced relief, he developed a high-grade fever. A comprehensive fever work-up found no apparent cause of the fever, except for PMF.[ncbi.nlm.nih.gov]

  • Brucellosis

    Brucellosis is a systemic zoonotic infectious disease that may cause fever, fatigue, sweating, arthritis, hepatosplenomegaly, cytopenia, and lymphadenopathy.[ncbi.nlm.nih.gov] Physical examination of the patient revealed massive hepatomegaly.[ncbi.nlm.nih.gov] Pancytopenia improved with treatment of brucellosis on all patients.[ncbi.nlm.nih.gov] Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease caused by a virus that is transmitted to humans by ixoid tick bites, contact with blood and tissue of infected[ncbi.nlm.nih.gov]

  • Adult-Onset Still Disease

    Other common manifestations of AOSD are lymphadenopathy, hepatosplenomegaly, muscle aches, and pharyngitis.[symptoma.com] RHS can be considered when an AOSD patient shows at least 2 of the following 3 findings: low platelet count, anemia, and hepatomegaly.[ncbi.nlm.nih.gov] This disorder is characterized by fever, pancytopenia, liver failure, coagulopathy, and neurologic symptoms.[ncbi.nlm.nih.gov] We conducted the current study to evaluate the cases of fever of unknown origin (FUO) admitted in our institution during the 10 years between 1991 and 2001 and to compare[ncbi.nlm.nih.gov]

  • Visceral Leishmaniasis

    Additionally an atypical presentation such as lymphadenopathy in VL should arouse suspicion of HIV co-infection and vice versa.[ncbi.nlm.nih.gov] The features of VL may be different in immunosuppressed patients, with more fever and less hepatomegaly and leukopenia than in HIV-infected patients.[ncbi.nlm.nih.gov] We present an unusual case of febrile pancytopenia in a nonagenarian who was diagnosed with visceral leishmaniasis.[ncbi.nlm.nih.gov] Surprisingly, fever started after beginning of meglumine antimoniate treatment in this patient.[ncbi.nlm.nih.gov]

  • Malignant Histiocytosis

    Four months after the operation, skin induration on the neck and anterior thoracic wall and systemic lymphadenopathy were noted.[ncbi.nlm.nih.gov] Most patients presented with systemic symptoms and lymphadenopathy (92%), splenomegaly (100%) and hepatomegaly (67%).[ncbi.nlm.nih.gov] […] pancreas at initial presentation is exceptional, this entity should be included in the differential diagnosis of acute pancreatitis, especially when hepatosplenomegaly and pancytopenia[ncbi.nlm.nih.gov] A 70-year-old woman was admitted for evaluation of hepatosplenomegaly, fever and elevated serum LDH levels.[ncbi.nlm.nih.gov]

  • Mantle Cell Lymphoma

    Fatigue, generalized lymphadenopathy and splenomegaly are its typical features.[symptoma.com] Characteristics at diagnosis involved lymphadenopathy (82%), splenomegaly (44%), B-symptoms (39%), and hepatomegaly (10%).[ncbi.nlm.nih.gov] He had fever, night sweats, and weight loss (B-symptoms), along with lymphadenopathy and elevated serum lactate dehydrogenase, with no prior history of lymphoma.[ncbi.nlm.nih.gov] Signs and symptoms of MCL may include fever , night sweats , enlarged lymph nodes , fatigue , splenomegaly ( enlarged spleen ), hepatomegaly ( enlarged liver ), and weight[rxlist.com]

  • Severe Combined Immunodeficiency

    This report emphasizes the importance of lymphadenopathy as a sentinel sign of immunological disorders.[ncbi.nlm.nih.gov] Systemic examination was remarkable with spleno-hepatomegaly but other systems were essentially normal.[omicsonline.org] His pancytopenia resolved after thymoglobulin and a stem cell boost. Thrombocytopenia resolved with rituximab.[ncbi.nlm.nih.gov] Both patients presented similar signs and symptoms (fever, skin rash, diarrhea, pancytopenia, and icterus). Skin biopsies demonstrated Grade II GVHD involvement.[ncbi.nlm.nih.gov]

  • Schistosomiasis

    Hepatospenomegaly and lymphadenopathy may be present. Symptoms usually resolve spontaneously over weeks.[rch.org.au] Pediátrica, Hospital Universitario Vall d’Hebron, Barcelona, Spain Article An 11-year-old black girl from Equatorial Guinea was admitted to our hospital to investigate fatigue, hepatomegaly[revespcardiol.org] At RITM, liver function tests were within normal limits but complete blood examinations showed pancytopenia and abnormal coagulation times.[ncbi.nlm.nih.gov] […] hand is schistosomiasis -- also known as bilharzia -- a chronic infection caused by parasitic Schistomosa worms that can live inside blood vessels for years on end causing fever[cnn.com]

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