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1,809 Possible Causes for Fever, Hepatosplenomegaly, Lymphadenopathy

  • Infectious Mononucleosis

    Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy[ncbi.nlm.nih.gov] To depict the grey-scale and Doppler features of cervical lymphadenopathy due to infectious mononucleosis (IM) and to compare the findings with other benign conditions and[ncbi.nlm.nih.gov] You don't usually get glandular fever more than once.[nhs.uk]

  • Pharyngitis

    Presence of hepatosplenomegaly or lymphadenopathy outside the cervical region should raise suspicions regarding an underlying malignancy.[ncbi.nlm.nih.gov] Most of these children have undergone workup(s) for sepsis performed by their pediatricians because of the associated high fever.[ncbi.nlm.nih.gov] When streptococcal pharyngitis is suspected, the physician should listen for the presence of a heart murmur and evaluate the patient for hepatosplenomegaly.[aafp.org]

  • Tuberculosis

    He had mild pallor with mild hepatosplenomegaly. He had high inflammatory markers with pancytopenia in a peripheral blood smear.[ncbi.nlm.nih.gov] In conclusion, TB-chylothorax may develop without obvious mediastinal lymphadenopathy and be associated with tubercular empyema alone.[ncbi.nlm.nih.gov] Tuberculosis (TB), especially extrapulmonary tuberculosis (EPTB), is an important cause of fever of unknown origin (FUO) in TB-burdened areas.[ncbi.nlm.nih.gov]

  • Severe Combined Immunodeficiency

    His brother, patient 2, was born preterm with a severe neonatal erythroderma, hepatosplenomegaly and lymphadenopathy.[ncbi.nlm.nih.gov] This report emphasizes the importance of lymphadenopathy as a sentinel sign of immunological disorders.[ncbi.nlm.nih.gov] Both patients presented similar signs and symptoms (fever, skin rash, diarrhea, pancytopenia, and icterus). Skin biopsies demonstrated Grade II GVHD involvement.[ncbi.nlm.nih.gov]

  • Adult-Onset Still Disease

    Other common manifestations of AOSD are lymphadenopathy, hepatosplenomegaly, muscle aches, and pharyngitis.[symptoma.com] We conducted the current study to evaluate the cases of fever of unknown origin (FUO) admitted in our institution during the 10 years between 1991 and 2001 and to compare[ncbi.nlm.nih.gov] Intense pruritus and linear erythematous lesions flared with a spiking fever, usually in the late afternoon and evening.[ncbi.nlm.nih.gov]

  • Chronic Lymphocytic Leukemia

    III Lymphocytosis; lymphadenopathy; hepatosplenomegaly, anemia IV Lymphocytosis, lymphadenopathy; hepatosplenomegaly, thrombocytopenia anemia CHRONIC LYMPHOCYTIC LEUKEMIA[medical-dictionary.thefreedictionary.com] Lymphadenopathy may or may not be present. Stage III: Absolute lymphocytosis with anemia is present. Hepatosplenomegaly and lymphadenopathy may or may not be present.[symptoma.com] The symptoms of this infection range from a silent infection to fever, enlargement of the liver and spleen, weight loss, and pancytopenia.[ncbi.nlm.nih.gov]

  • Multicentric Castleman's Disease

    Multicentric Castleman's disease (MCD) typically presents with constitutional symptoms, generalized peripheral lymphadenopathy, hepatosplenomegaly, and laboratory markers[ncbi.nlm.nih.gov] ORPHA:93686 Synonym(s): MCD Multicentric giant lymph node hyperplasia Prevalence: - Inheritance: - Age of onset: - ICD-10: D36.0 OMIM: 148000 UMLS: C1334815 MeSH: C537372[orpha.net] A 67-year-old man had six hospital admissions over 20 months characterised by fever, urinary frequency and CRP 100 mg/L.[ncbi.nlm.nih.gov]

  • T-Cell Lymphoma

    Hepatosplenomegaly and systemic lymphadenopathy were detected by enhanced computed tomography.[ncbi.nlm.nih.gov] Case one is a 19-year-old female presented with fever and liver dysfunction, and was diagnosed as EBV-associated chronic active hepatitis.[ncbi.nlm.nih.gov] Clinically absent hepatosplenomegaly and skin lesions with biopsy-proven gamma-delta T-cell lymphoma suggest that she is unclassifiable within the current classification system[ncbi.nlm.nih.gov]

  • Castleman Disease

    For multicentric disease: multi-region CT bilateral hilar and mediastinal lymphadenopathy centrilobular nodules diffuse abdominal lymphadenopathy hepatosplenomegaly ascites[radiopaedia.org] Castleman disease, also known as angiofollicular lymph node hyperplasia and giant lymph node hyperplasia, represents a group of non-neoplastic lymphoproliferative disorders[symptoma.com] A 46-year-old male patient presented with fever for over 5 months. An FDG PET/CT was acquired to evaluate the source of the fever.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] Although ruxolitinib rapidly induced relief, he developed a high-grade fever. A comprehensive fever work-up found no apparent cause of the fever, except for PMF.[ncbi.nlm.nih.gov]

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