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2,053 Possible Causes for Fever, Hepatosplenomegaly, Seizure

  • Infectious Mononucleosis

    Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy[ncbi.nlm.nih.gov] If the patient has seizures or any seizure like activity, an EEG may help rule out other causes of encephalitis.[symptoma.com] You don't usually get glandular fever more than once.[nhs.uk]

  • African Trypanosomiasis

    Abdominal and pelvic MRI showed hepatosplenomegaly and multiple enlarged lymph nodes.[ncbi.nlm.nih.gov] The illness progresses after a few weeks to weight loss, as well as personality changes, slurred speech, seizures, difficulty balancing and walking resulting from central[iamat.org] A 61-year-old Polish man was admitted to the Department because of high-grade fever and multi-organ dysfunction after a tourist trip to East Africa.[ncbi.nlm.nih.gov]

  • Congenital Syphilis

    A previously healthy male infant developed hepatosplenomegaly, severe anaemia and thrombocytopenia 5 weeks after birth.[ncbi.nlm.nih.gov] […] characteristic skin lesions, lymphadenopathy, hepatosplenomegaly, failure to thrive, blood-stained nasal discharge, perioral fissures, meningitis, choroiditis, hydrocephalus, seizures[msdmanuals.com] Although rare, bow legs, recurrent fever, anemia, and inflammatory arthralgias may be manifestations of late CS.[ncbi.nlm.nih.gov]

  • Tuberculosis

    He had mild pallor with mild hepatosplenomegaly. He had high inflammatory markers with pancytopenia in a peripheral blood smear.[ncbi.nlm.nih.gov] For one of these colleagues, the bacteria spread to his brain and he had seizures on the hospital floor in front of patients, Desai said.[rewire.org] Tuberculosis (TB), especially extrapulmonary tuberculosis (EPTB), is an important cause of fever of unknown origin (FUO) in TB-burdened areas.[ncbi.nlm.nih.gov]

  • Brucellosis

    Brucellosis is a systemic zoonotic infectious disease that may cause fever, fatigue, sweating, arthritis, hepatosplenomegaly, cytopenia, and lymphadenopathy.[ncbi.nlm.nih.gov] We report a rare case of brucellosis with Parkinsonian-like tremor and simple partial motor seizure.[ncbi.nlm.nih.gov] Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease caused by a virus that is transmitted to humans by ixoid tick bites, contact with blood and tissue of infected[ncbi.nlm.nih.gov]

  • Cryopyrin-Associated Periodic Syndrome

    Patients may have lymphadenopathy and/or hepatosplenomegaly. The CINCA/NOMID syndrome typically presents shortly after birth.[clevelandclinicmeded.com] Onset, severity and complications (mainly retardation, seizures, destructive arthropathy and amyloidosis) depend on the specific mutation.[ncbi.nlm.nih.gov] Herein, we present the case of a 9-month-old boy with recurrent nonpruritic rashes and episodes of fever.[ncbi.nlm.nih.gov]

  • CINCA Syndrome

    The patient was a male who was first seen at the age of 8-years for hepatosplenomegaly.[cags.org.ae] Headache, vomiting, altered mental state, intellectual disability, seizures, episodes of hemiplegia and chronic meningitis-like states are CNS manifestations of the disease[symptoma.com] CINCA syndrome is a genetic disorder characterized by early onset of recurrent fever, rash, progressive articular and neurological involvement.[ncbi.nlm.nih.gov]

  • Otitis Media

    Bowel sounds present in all 4 quadrants, no hepatosplenomegaly MSK: Full range of motion in all extremeties Comparing the left and right sides of the ear helps in pinpointing[npstudent.com] Symptoms of a brain abscess can include: a severe headache changes in mental state, such as confusion weakness or paralysis on one side of the body a high temperature (fever) seizures[nhsinform.scot] We describe the youngest case to date of a 2 year old child who developed central skull base osteomyelitis (SBO) initially presenting with a fever, vomiting and sore throat[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Extramedullary hematopoiesis may involve any organ and may result in gastrointestinal bleeding, spinal cord compression, seizures, haemoptysis, and/or effusions.[patient.info] Although ruxolitinib rapidly induced relief, he developed a high-grade fever. A comprehensive fever work-up found no apparent cause of the fever, except for PMF.[ncbi.nlm.nih.gov]

  • Kawasaki Disease

    In addition to the cardiac problem, hypoalbuminaemia, electrolyte imbalance, sterile pyuria, hepatosplenomegaly, and hydrops of the gallbladder were observed in the case.[ncbi.nlm.nih.gov] This indicated acute encephalopathy with biphasic seizures and late reduced diffusion (AESD); severe neurological sequelae remained.[ncbi.nlm.nih.gov] A 5-year-old girl who presented with fever that was confirmed to be dengue fever, and subsequently improved, except that the fever persisted.[ncbi.nlm.nih.gov]

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