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915 Possible Causes for Fever, Leukocytosis, Thrombocytosis

  • Primary Myelofibrosis

    Objectives: To compare the mutational profiles of patients with primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocytosis (ET).[ncbi.nlm.nih.gov] Although ruxolitinib rapidly induced relief, he developed a high-grade fever. A comprehensive fever work-up found no apparent cause of the fever, except for PMF.[ncbi.nlm.nih.gov] Leukocytosis is occasionally seen in patients with presumptive but undiagnosed myeloproliferative disorders (MPD).[ncbi.nlm.nih.gov]

  • Adult-Onset Still Disease

    Both patients had marked leukocytosis with neutrophil predominance, thrombocytosis, elevated liver enzymes and elevated acute phase rectants.[ajol.info] Intense pruritus and linear erythematous lesions flared with a spiking fever, usually in the late afternoon and evening.[ncbi.nlm.nih.gov] AOSD) is a systemic inflammatory disease characterized by high-fevers, articular involvement, maculopapular rash, hepatosplenomegaly, lymphadenopathy, and a neutrophilic leukocytosis[ncbi.nlm.nih.gov]

  • Chronic Phase of Chronic Myeloid Leukemia

    Extreme thrombocytosis was present, although no evidence of acquired von Willebrand disorder was found.[ncbi.nlm.nih.gov] In the accelerated phase, the number of CML cells is growing faster and causing symptoms such as fatigue, fever, weight loss and an enlarged spleen.[lls.org] CP-CML patients are generally asymptomatic and diagnosis of the disease is based on the incidental detection of hematological alterations: While leukocytosis 50*10 9/l is[symptoma.com]

  • Temporal Arteritis

    Laboratory abnormalities associated with TA include a highly elevated erythrocyte sedimentation rate, anemia, and thrombocytosis, and mildly increased alkaline phosphatase[ncbi.nlm.nih.gov] […] description derived from examining 2 patients: Both patients were admitted to the Clinic in the spring of 1931 because of fever, weakness, anorexia, loss of weight, anemia, mild leukocytosis[medlink.com] Hayreh 2003 points out that although essential thrombocytosis has increased thrombotic morbidity, the thrombocytosis in GCA is reactive and thus an antithrombotic agent is[doi.org]

  • Chronic Myeloid Leukemia

    A 10-year-old boy presented with spontaneous bruising and was found to have extreme thrombocytosis without neutrophilia/shift to immaturity, basophilia or eosinophilia.[ncbi.nlm.nih.gov] Fever, enlarged lymph nodes, an increase in immature white blood cells, and certain skin rashes are usually signs of advanced disease.[merck.com] Her disease was managed during pregnancy using interferon-α alone despite persistent leukocytosis.[ncbi.nlm.nih.gov]

  • Hereditary Spherocytosis

    It also results in leukocytosis and thrombocytosis. On peripheral blood smear, spherocytes are unchanged or may even increase.[medcaretips.com] A 33-year-old woman with hereditary spherocytosis and gallstones was admitted because of rapid progress in marked anemia and fever.[ncbi.nlm.nih.gov] Reticulocytosis of 15 to 30% and leukocytosis are common.[merckmanuals.com]

  • Henoch-Schönlein Purpura

    […] have been reported include esophageal stenosis, hemorrhagic pancreatitis, protein-losing enteropathy, pulmonary function abnormalities, pulmonary and pleural hemorrhage, thrombocytosis[jasn.asnjournals.org] Henoch Schönlein purpura (HSP) with acute rheumatic fever (ARF) is a rare entity and only few cases have been reported so far.[ncbi.nlm.nih.gov] Laboratory tests showed leukocytosis, proteinuria, and elevated creatinine. A skin biopsy revealed small-vessel neutrophilic vasculitis.[circ.ahajournals.org]

  • Splenic Infarction

    Changes in the blood count included anemia (53%), leukocytosis (49%), and thrombocytosis (7%).[ncbi.nlm.nih.gov] Recent data suggest that antiphospholipid antibodies may be responsible for certain clinical manifestations of acute Q fever.[ncbi.nlm.nih.gov] A post hoc analysis demonstrated that single infarcts were more likely to be associated with fever (20% vs. 63%, p 0.05) and leukocytosis (75% vs. 33%, P 0.06) CONCLUSIONS[ncbi.nlm.nih.gov]

  • Granulomatosis with Polyangiitis

    […] conjunctivitis corneal ulceration skin lesions at high risk of DVT EXAMINATION pleural effusions pulmonary infiltrates skin vasculitis lesions INVESTIGATIONS leucocytosis thrombocytosis[lifeinthefastlane.com] Seven months later, he was hospitalized with symptoms of cough, high-grade fever, and loss of weight.[ncbi.nlm.nih.gov] A normocytic anemia, leukocytosis, elevated erythrocyte sedimentation rate, positive rheumatoid factor and ANCA (specifically PR3-ANCA) are often shown on serology.[jacpjournal.org]

  • Acute Myelocytic Leukemia

    Here we report a case of AML with thrombocytosis arising in a patient with this syndrome.[ncbi.nlm.nih.gov] A patient with acute nonlymphocytic leukemia developed progressive lung infiltrates and unremitting fevers during a profound neutropenic state.[ncbi.nlm.nih.gov] Thus, the bone marrow and peripheral blood are characterized by leukocytosis with a predominance of immature cells, primarily blasts.[ncbi.nlm.nih.gov]

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