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242 Possible Causes for Fever, Massive Splenomegaly, Pancytopenia

  • Primary Myelofibrosis

    She also underwent splenectomy when she was 13 years old, due to massive splenomegaly, anemia and various infection disease episodes.[ncbi.nlm.nih.gov] This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[aoporphan.com] Although ruxolitinib rapidly induced relief, he developed a high-grade fever. A comprehensive fever work-up found no apparent cause of the fever, except for PMF.[ncbi.nlm.nih.gov]

  • Leukemia

    Splenomegaly can be massive, consistency high, with the fibrous thickening of the capsule.[ncbi.nlm.nih.gov] This fact sheet discusses the theory that intermittent fasting may reduce the risk of cancer or improve outcomes with anticancer treatments. more » A 47-Year-Old Woman with Pancytopenia[cancertherapyadvisor.com] fever on day 29.[bloodjournal.hematologylibrary.org]

  • Chronic Lymphocytic Leukemia

    splenomegaly and occasionally lymphadenopathy; prognosis is often poor.[medical-dictionary.thefreedictionary.com] Brentuximab vedotin had a transient effect, but the patient died of sepsis due to residual PTCL and pancytopenia.[ncbi.nlm.nih.gov] The symptoms of this infection range from a silent infection to fever, enlargement of the liver and spleen, weight loss, and pancytopenia.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    We describe a patient under treatment with the anti-complement antibody eculizumab who developed pancytopenia, requiring blood transfusions, due to massive splenomegaly.[ncbi.nlm.nih.gov] We report a 19-year-old female patient admitted to the hospital with pancytopenia. Workout of pancytopenia disclosed paroxysmal nocturnal hemoglobinuria.[ncbi.nlm.nih.gov] Thromboses, as observed in our case, may be associated with fever and marked inflammation.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    Here, we report a case of aCMLin a 5-month baby who presented with massive splenomegaly. The diagnosis was in accordance with the WHO criteria established in 2008.[ncbi.nlm.nih.gov] We present a case of 29-year-old white male farmer, with chronic myeloid leukemia treated with imatinib who developed significant pancytopenia, leading to discontinuation[ncbi.nlm.nih.gov] Fever, enlarged lymph nodes, an increase in immature white blood cells, and certain skin rashes are usually signs of advanced disease.[merck.com]

  • Mantle Cell Lymphoma

    Splenomegaly is often massive, while aberrant WBC count may be seen, either as markedly high leukocytosis or pancytopenia.[symptoma.com] He had fever, night sweats, and weight loss (B-symptoms), along with lymphadenopathy and elevated serum lactate dehydrogenase, with no prior history of lymphoma.[ncbi.nlm.nih.gov] IIA), where B means presence of B symptoms (see below) while A means abscence of the following symptoms: Unexplained a href ”/fever/” fever 38 Centigrade Unexplained weight[myvmc.com]

  • Visceral Leishmaniasis

    ., infection with Leishmania sp. associated with high fever, weight loss, massive splenomegaly and markedly altered laboratory parameters, is generally fatal if untreated.[ncbi.nlm.nih.gov] We present an unusual case of febrile pancytopenia in a nonagenarian who was diagnosed with visceral leishmaniasis.[ncbi.nlm.nih.gov] Surprisingly, fever started after beginning of meglumine antimoniate treatment in this patient.[ncbi.nlm.nih.gov]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    […] included thrombocytopenia (n 8), diarrhea (n 3), alanine aminotransferase elevation (n 3), aspartate aminotransferase elevation (n 2), dyspnea (n 2), neutropenia (n 2), pancytopenia[bloodjournal.org] Weight loss, fever, night sweats, and reduced exercise tolerance are common complaints.[symptoma.com] The absence of small tender asymmetric goiter, fever, dysphagia, and erythema over thyroid rules out bacterial or fungal causes of thyroiditis.[ijp-online.com]

  • Hepatosplenic Lymphoma

    Most patients had massive splenomegaly, and bone marrow showed sinusoidal involvement by lymphoma.[mdanderson.elsevierpure.com] Bone marrow infiltration results in pancytopenia .[wikidoc.org] , SM, fever, pancytopenia Ch.[wjgnet.com]

  • Chronic Phase of Chronic Myeloid Leukemia

    In the accelerated phase, the number of CML cells is growing faster and causing symptoms such as fatigue, fever, weight loss and an enlarged spleen.[lls.org] These patients often have fever, poor appetite, and weight loss. In this phase, the CML acts a lot like an acute leukemia.[cancer.org] Patients in blast phase often have a fever, an enlarged spleen, weight loss, and generally feel unwell. Resistant CML.[cancer.net]

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