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79 Possible Causes for Fiber Size Variability Increased

  • Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1F

    Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, an internationally renowned figure in the field of muscle disease, this[…][books.google.com]

  • Duchenne Muscular Dystrophy

    size: Varied Endomysial connective tissue: Increased Fat replacement of muscle: Prominent H&E stain VvG stain H&E stain Endomysial connective tissue : Increased Fiber size[neuromuscular.wustl.edu] : Variable Small fibers : Rounded Large or hypercontracted muscle fibers: Scattered Necrotic fibers (Arrow): Scattered Muscle fiber size: Varied Small & Large fibers: May[neuromuscular.wustl.edu] […] trichrome stain VvG stain DMD Many intermediate-stained muscle fibers ATPase pH 4.3 stain Duchenne Muscular Dystrophy: Later Pathology (10 years) H&E stain DMD: Later pathology Fiber[neuromuscular.wustl.edu]

  • Lafora Disease

    Treatment: Arginine Laboratory CK: High after exercise & anesthesia; Near normal otherwise EMG: Normal Muscle pathology Fiber size: Variable Lipid: Increased EM: Distorted[neuromuscular.wustl.edu] […] severity Myopathy: Fiber degeneration & Regeneration Increased glycogen in muscle fibers Mitochondria Increased Size & Number Abnormal shape & structure No ragged red fibers[neuromuscular.wustl.edu] […] biopsy: Loss of myelinated axons; Regeneration Joint contractures : Ankles Course Onset 2 years Majority die 6 years Respiratory failure ; Cardiomyopathy Muscle pathology: Variable[neuromuscular.wustl.edu]

  • Emery-Dreifuss Muscular Dystrophy

    SIGNIFICANCE: Irregular MUPs in EDMD most probably reflect increased variability of the muscle fiber size.[ncbi.nlm.nih.gov] Muscular biopsy of a deltoid muscle showed increased variability in muscle fiber size due to moderate numbers of atrophic and hypertrophic muscle fibers.[scielo.br] Muscle biopsy specimens revealed the variable muscle fiber size due to atrophy, hypertrophy, and muscle fiber splitting.[ncbi.nlm.nih.gov]

  • Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2T

    […] endomysial connective tissue 0100297 Increased variability in muscle fiber diameter 0003557 Lumbar hyperlordosis Excessive inward curvature of lower spine 0002938 Macroglossia[rarediseases.info.nih.gov] Abnormally large tongue Increased size of tongue Large tongue Weight control to avoid obesity Physical therapy and stretching exercises to promote mobility and prevent contractures[rarediseases.info.nih.gov] […] abnormalities. 0003236 EMG: myopathic abnormalities 0003458 EMG: myotonic discharges 0100284 EMG: myotonic runs 0003730 EMG: positive sharp waves 0030007 Frequent falls 0002359 Increased[rarediseases.info.nih.gov]

  • Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2C

    […] endomysial connective tissue 0100297 Increased variability in muscle fiber diameter 0003557 Lumbar hyperlordosis Excessive inward curvature of lower spine 0002938 Macroglossia[rarediseases.info.nih.gov] Abnormally large tongue Increased size of tongue Large tongue Weight control to avoid obesity Physical therapy and stretching exercises to promote mobility and prevent contractures[rarediseases.info.nih.gov] […] abnormalities. 0003236 EMG: myopathic abnormalities 0003458 EMG: myotonic discharges 0100284 EMG: myotonic runs 0003730 EMG: positive sharp waves 0030007 Frequent falls 0002359 Increased[rarediseases.info.nih.gov]

  • Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2J

    […] endomysial connective tissue 0100297 Increased variability in muscle fiber diameter 0003557 Lumbar hyperlordosis Excessive inward curvature of lower spine 0002938 Macroglossia[rarediseases.info.nih.gov] Abnormally large tongue Increased size of tongue Large tongue Weight control to avoid obesity Physical therapy and stretching exercises to promote mobility and prevent contractures[rarediseases.info.nih.gov] […] abnormalities. 0003236 EMG: myopathic abnormalities 0003458 EMG: myotonic discharges 0100284 EMG: myotonic runs 0003730 EMG: positive sharp waves 0030007 Frequent falls 0002359 Increased[rarediseases.info.nih.gov]

  • Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2L

    […] endomysial connective tissue 0100297 Increased variability in muscle fiber diameter 0003557 Lumbar hyperlordosis Excessive inward curvature of lower spine 0002938 Macroglossia[rarediseases.info.nih.gov] Abnormally large tongue Increased size of tongue Large tongue Weight control to avoid obesity Physical therapy and stretching exercises to promote mobility and prevent contractures[rarediseases.info.nih.gov] […] abnormalities. 0003236 EMG: myopathic abnormalities 0003458 EMG: myotonic discharges 0100284 EMG: myotonic runs 0003730 EMG: positive sharp waves 0030007 Frequent falls 0002359 Increased[rarediseases.info.nih.gov]

  • Sarcotubular Myopathy

    Other histological findings include hypotrophy and predominance of type I fibers, variability in fiber size, and a slight increase in the connective tissue 7 .[scielo.br] Another frequent finding in CNM is the increased variability in fiber size where there are hypotrohied fibers usually in a great number adjacent to normal size and hypertrophied[scielo.br]

  • Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2F

    […] endomysial connective tissue 0100297 Increased variability in muscle fiber diameter 0003557 Lumbar hyperlordosis Excessive inward curvature of lower spine 0002938 Macroglossia[rarediseases.info.nih.gov] Abnormally large tongue Increased size of tongue Large tongue Weight control to avoid obesity Physical therapy and stretching exercises to promote mobility and prevent contractures[rarediseases.info.nih.gov] […] abnormalities. 0003236 EMG: myopathic abnormalities 0003458 EMG: myotonic discharges 0100284 EMG: myotonic runs 0003730 EMG: positive sharp waves 0030007 Frequent falls 0002359 Increased[rarediseases.info.nih.gov]

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