Abstract A 1-month-old Japanese girl had profound generalized weakness, hypotonia, and severe lactic acidosis. The infant improved gradually: she held her head at 9 months, learned to walk by 15 months. At the first muscle biopsy at 11 weeks of age, the specimen was characterized by numerous ragged-red fibers and[…]
[ncbi.nlm.nih.gov]
Moreover, increased protein turnover was also detected in fibrotic lung tissue of IPF patients.
[sciencedaily.com]
Typically, patients are in their forties and fifties when diagnosed while the incidence of idiopathic pulmonary fibrosis increases dramatically after the age of fifty.
[en.wikipedia.org]
Strikingly, ibrutinib did not inhibit but exacerbated bleomycin-induced pulmonary fibrosis by increased epithelial cell apoptosis, and inflammation in the lung.
[ncbi.nlm.nih.gov]
or immunodeficiency) increase the risk and severity of infection Epidemiology United States statistics Common colds are most frequent from September to April in temperate
[emedicine.medscape.com]
Underlying chronic medical conditions, including anatomic, metabolic, genetic, and immunologic disorders (eg, tracheoesophageal fistula, congenital heart disease, cystic fibrosis
[emedicine.medscape.com]
BACKGROUND: Syndecan-4 is a transmembrane glycoprotein associated with inflammation and fibrosis.
[ncbi.nlm.nih.gov]
RESULTS: Myocardial fibrosis was not significantly increased in Chol or Meth.
[vuir.vu.edu.au]
fibrosis increases ( 14, 15 ).
[eje.bioscientifica.com]
[…] necrosis and fibrosis of the respiratory tract.
[icd9data.com]
Risk increases multiplicatively if an exposed person also smokes.
[cdc.gov]
Condition characterized by persistent coughing, increased secretion from the bronchial mucosa, obstruction of the respiratory passages, scanty or profuse expectoration, and
[icd9data.com]
[…] necrosis and fibrosis of the respiratory tract.
[icd9data.com]
Risk increases multiplicatively if an exposed person also smokes.
[cdc.gov]
Condition characterized by persistent coughing, increased secretion from the bronchial mucosa, obstruction of the respiratory passages, scanty or profuse expectoration, and
[icd9data.com]
TGF-β1 has been shown to increase mitochondrial ROS production in different cell types, which mediate fibrosis related gene expression and myofibroblast differentiation.
[ncbi.nlm.nih.gov]
Serum vitamin D deficiency may increase the risk of early and late AMD in Koreans, and may also be associated with subretinal fibrosis in this population.
[ncbi.nlm.nih.gov]
Abstract The increase in asthma and allergies prevalence that has been recorded in many countries during the last decades, and the reemergence of vitamin D (VD) deficiency
[ncbi.nlm.nih.gov]
People with asthma and allergic rhinitis are more likely to develop URI Smoking is a common risk factor for URI Immunocompromised individuals including those with cystic fibrosis
[ncbi.nlm.nih.gov]
use of corticosteroids, transplantation, and post-splenectomy are at high risk for URI Anatomical anomalies including facial dysmorphic changes or nasal polyposis also increase
[ncbi.nlm.nih.gov]
People with asthma and allergic rhinitis are more likely to develop URI Smoking is a common risk factor for URI Immunocompromised individuals including those with cystic fibrosis
[ncbi.nlm.nih.gov]
use of corticosteroids, transplantation, and post-splenectomy are at high risk for URI Anatomical anomalies including facial dysmorphic changes or nasal polyposis also increase
[ncbi.nlm.nih.gov]
Calcium oxalate deposition had a significant influence on interstitial fibrosis development, therefore negatively affecting graft survival.
[ncbi.nlm.nih.gov]
CONCLUSIONS: Calcium oxalate deposits increased the risk of urinary tract infection and tubulointerstitial nephritis, with bacteria inducing increased presence of calcium
[ncbi.nlm.nih.gov]
Risk factors: increased age female parity obesity diabetes mellitus profound weight loss fasting cystic fibrosis malabsorption syndromes familial various medication (oral
[aci.health.nsw.gov.au]
Our findings indicate that the inhibition of miR-214 promotes the EMT process and contributes to bladder wall fibrosis by up-regulating Mfn2, thus leading to the occurrence
[ncbi.nlm.nih.gov]
[…] expression levels of N-cadherin, Fibronectin, Twist1, Snail and Vimentin mRNA and protein decreased, whereas the expression levels of Mfn2, E-cadherin and ZO-1 mRNA and protein increased
[ncbi.nlm.nih.gov]
As patients with CF live longer and fuller lives, increasing encumbrances from gastrointestinal manifestations of CF will be observed.
[ncbi.nlm.nih.gov]
Foundation Patient Registry (CFFPR) was founded, clinicians have witnessed significant advances in both the quality and quantity of life for patients living with Cystic Fibrosis
[ncbi.nlm.nih.gov]
Combination of diabetes and non-alcoholic fatty liver disease may increase liver fibrosis risk New research has uncovered that fatty liver and diabetes influence fibrosis.
[belmarrahealth.com]
In this cohort study, we investigated whether platelets' increase after entecavir (ETV) therapy was associated with the improvement of liver fibrosis.
[ncbi.nlm.nih.gov]
Secondary aims were to assess the diagnostic accuracy of ELF for significant fibrosis and cirrhosis and to determine whether combinations of fibrosis markers increase diagnostic
[ncbi.nlm.nih.gov]
In some populations, family history of pulmonary fibrosis or hypersensitivity pneumonitis may increase the risk of developing hypersensitivity pneumonitis.
[nhlbi.nih.gov]
Eighteen months after disease onset there was scarring of the penis together with suspected fibrosis of the inflamed gingival region.
[ncbi.nlm.nih.gov]
In addition the patient was HLA DQ7(3) positive, a haplotype thought to be increased in patients with cicatricial pemphigoid (CP); LAD with scarring or CP with solely linear
[ncbi.nlm.nih.gov]
[…] surgery cirrhosis, which involves scarring of the liver fibrosis, or scar tissue, within the bone marrow hemolysis, which is the rupture of red blood cells that can occur
[healthline.com]
Factors that increase red blood cell destruction include: hemorrhage from: endometriosis accidents gastrointestinal lesions menstruation childbirth excessive uterine bleeding
[healthline.com]
[…] left atrial (LA) volume, fibrosis and fat content, reduced LA conduction velocity, and increased AFV and AF duration. 33, 35 A unique AF substrate is seen with sustained
[doi.org]
[…] vascular dysfunction, cardiac fibrosis, and increased risk of myocardial infarction and stroke. 31 Chronic treatment of hypertensive rats with mineralocorticoid receptor
[doi.org]
AF), increased left ventricular hypertrophy (LVH) and diastolic dysfunction, increased stiffness of large arteries, widespread tissue fibrosis, increased remodeling of resistance
[doi.org]
increased IgG4 plasma cells.
[ncbi.nlm.nih.gov]
Cystic fibrosis has a genetic defect and increased mucin, which are potential treatment targets with dornase alfa showing efficacy.
[mdpi.com]
Although initial concern was greatest for malignancy, a biopsy specimen confirmed the presence of a dense lymphoplasmacytic infiltrate and storiform fibrosis, associated with
[ncbi.nlm.nih.gov]
Over time, fibrosis may occur, further contributing to the poor compliance of the ventricle.
[emedicine.medscape.com]
As the left ventricle does not relax during early diastole, left ventricular end-diastolic pressure increases, further increasing left atrial pressure in late diastole.
[emedicine.medscape.com]
Studies show alcohol use can affect these parts of the body: High blood pressure, irregular heartbeat, stroke Inflammation, including alcoholic hepatitis, fibrosis, cirrhosis
[gatewayfoundation.org]
Acute kidney failure and chronic kidney disease Inflammation and swelling of blood vessels that prevent proper digestion Increased susceptibility to diseases such as tuberculosis
[gatewayfoundation.org]
Multiple mechanisms may be responsible for this syndrome, including (1) impaired endothelial dysfunction, [9] (2) increased release of local vasoconstrictors, (3) fibrosis
[emedicine.medscape.com]
Chronic diseases may be associated with nutrient loss, increased nutrient demand, and/or malabsorption.
[labtestsonline.org]
[…] the body's demand for energy Examples of these types of conditions include childhood cancers, congenital heart disease, cystic fibrosis and cerebral palsy.
[nhs.uk]
An increased loss of nutrients may be seen with chronic kidney disease, diarrhea and excessive bleeding.
[labtestsonline.org]
It is further mentioned that along with another cytokine, TGF-β1 increases fibrosis and scarring around tuberculous lesion leading to reduced function of the lung parenchyma
[lungindia.com]
These results suggest that TGF-β1 level is most dominant in patients with extensive fibrosis lesion of the lung.
[lungindia.com]
Moreover, the mean plasma level of TGF-β1 was significantly increased in the group with extensive lesion compared with the group with minimal lesion.
[lungindia.com]
We found increased levels of HbA1c (p 0.054) and HOMA-IR (0.001) in the group with NAFLD as well.
[dx.doi.org]
Ghorbel, Relation entre stéatose, activité et fibrose au cours de l’hépatite chronique C Relationship between steatosis, inflammation and fibrosis in chronic hepatitis C,
[doi.org]
Ballestri et al. evaluated obese patients using ultrasonography and found a relationship between HOMA-IR and insulin in patients with NAFLD, except in individuals with fibrosis
[dx.doi.org]
following radiation therapy, significant fibrosis from prior vaginal surgery, severe atrophy) are at increased risk for complications following synthetic mesh placement
[auanet.org]
Compromised tissue may heal poorly, thereby increasing the risk for complications when mesh is placed.
[auanet.org]
Subepithelial fibrosis and increased expression of transforming growth factor B (TGF-B) are also observed.
[globalgenes.org]
Often starting in childhood with eating difficulties and symptoms of gastroesophageal reflux disease, it progresses with increasing inflammation, fibrosis, and strictures
[mdedge.com]
Abstract Eosinophilic esophagitis (EoE) is rare but incidence and prevalence is increasing.
[ncbi.nlm.nih.gov]
[…] with advancing stage of fibrosis.
[ncbi.nlm.nih.gov]
More advanced fibrosis is accompanied by increased TNF-α expression [ 38 ].
[dx.doi.org]
Ghorbel, Relation entre stéatose, activité et fibrose au cours de l’hépatite chronique C Relationship between steatosis, inflammation and fibrosis in chronic hepatitis C,
[doi.org]
Conditions that increase the permeability of the small intestinal mucosa to proteins such as viral gastroenteritis, premature birth, and cystic fibrosis also seem to increase
[farrp.unl.edu]
[…] levels of subepithelial fibrosis and increased expression of TGF-b1 and its signaling molecule phospho-SMAD2/3 compared with patients with GERD and normal subjects.
[dx.doi.org]
All seven EoE patients demonstrated subepithelial fibrosis (4 severe, 3 moderate) on trichrome staining.
[dx.doi.org]
[…] and increased reactive oxygen radicals.( 3 - 6 ) Hyperuricemia and secondary (saturnine) gout are common findings associated with chronic lead toxicity and they are thought
[archivesofrheumatology.org]
Both factors are well-known related to progression of kidney disease.2 Epidemiological studies have recently shown the association between serum uric acid levels and increased
[revistanefrologia.com]
[…] rheumatic entity due to chronic lead toxicity.( 3 ) Previous studies have established that lead exposure causes renal dysfunction via direct tubular damage, tubulointerstitial fibrosis
[archivesofrheumatology.org]
