Fibrosis Increased Causes & Reasons

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Fibrosis Increased Symptom Checker: Possible causes include Mitochondrial Myopathy with Reversible Cytochrome C Oxidase Deficiency. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Mitochondrial Myopathy with Reversible Cytochrome C Oxidase Deficiency

Abstract A 1-month-old Japanese girl had profound generalized weakness, hypotonia, and severe lactic acidosis. The infant improved gradually: she held her head at 9 months, learned to walk by 15 months. At the first muscle biopsy at 11 weeks of age, the specimen was characterized by numerous ragged-red fibers and[…] [ncbi.nlm.nih.gov]

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Pulmonary Fibrosis

Moreover, increased protein turnover was also detected in fibrotic lung tissue of IPF patients. [sciencedaily.com]

Typically, patients are in their forties and fifties when diagnosed while the incidence of idiopathic pulmonary fibrosis increases dramatically after the age of fifty. [en.wikipedia.org]

Strikingly, ibrutinib did not inhibit but exacerbated bleomycin-induced pulmonary fibrosis by increased epithelial cell apoptosis, and inflammation in the lung. [ncbi.nlm.nih.gov]

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Common Cold

or immunodeficiency) increase the risk and severity of infection Epidemiology United States statistics Common colds are most frequent from September to April in temperate [emedicine.medscape.com]

Underlying chronic medical conditions, including anatomic, metabolic, genetic, and immunologic disorders (eg, tracheoesophageal fistula, congenital heart disease, cystic fibrosis [emedicine.medscape.com]

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Myocardial Fibrosis

BACKGROUND: Syndecan-4 is a transmembrane glycoprotein associated with inflammation and fibrosis. [ncbi.nlm.nih.gov]

RESULTS: Myocardial fibrosis was not significantly increased in Chol or Meth. [vuir.vu.edu.au]

fibrosis increases ( 14, 15 ). [eje.bioscientifica.com]

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Bronchitis

[…] necrosis and fibrosis of the respiratory tract. [icd9data.com]

Risk increases multiplicatively if an exposed person also smokes. [cdc.gov]

Condition characterized by persistent coughing, increased secretion from the bronchial mucosa, obstruction of the respiratory passages, scanty or profuse expectoration, and [icd9data.com]

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Acute Bronchitis

[…] necrosis and fibrosis of the respiratory tract. [icd9data.com]

Risk increases multiplicatively if an exposed person also smokes. [cdc.gov]

Condition characterized by persistent coughing, increased secretion from the bronchial mucosa, obstruction of the respiratory passages, scanty or profuse expectoration, and [icd9data.com]

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Vitamin D Deficiency

TGF-β1 has been shown to increase mitochondrial ROS production in different cell types, which mediate fibrosis related gene expression and myofibroblast differentiation. [ncbi.nlm.nih.gov]

Serum vitamin D deficiency may increase the risk of early and late AMD in Koreans, and may also be associated with subretinal fibrosis in this population. [ncbi.nlm.nih.gov]

Abstract The increase in asthma and allergies prevalence that has been recorded in many countries during the last decades, and the reemergence of vitamin D (VD) deficiency [ncbi.nlm.nih.gov]

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Viral Upper Respiratory Tract Infection

People with asthma and allergic rhinitis are more likely to develop URI Smoking is a common risk factor for URI Immunocompromised individuals including those with cystic fibrosis [ncbi.nlm.nih.gov]

use of corticosteroids, transplantation, and post-splenectomy are at high risk for URI Anatomical anomalies including facial dysmorphic changes or nasal polyposis also increase [ncbi.nlm.nih.gov]

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Upper Respiratory Infection

People with asthma and allergic rhinitis are more likely to develop URI Smoking is a common risk factor for URI Immunocompromised individuals including those with cystic fibrosis [ncbi.nlm.nih.gov]

use of corticosteroids, transplantation, and post-splenectomy are at high risk for URI Anatomical anomalies including facial dysmorphic changes or nasal polyposis also increase [ncbi.nlm.nih.gov]

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Urinary Tract Infection

Calcium oxalate deposition had a significant influence on interstitial fibrosis development, therefore negatively affecting graft survival. [ncbi.nlm.nih.gov]

CONCLUSIONS: Calcium oxalate deposits increased the risk of urinary tract infection and tubulointerstitial nephritis, with bacteria inducing increased presence of calcium [ncbi.nlm.nih.gov]

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Acute Alcohol Intoxication

Risk factors: increased age female parity obesity diabetes mellitus profound weight loss fasting cystic fibrosis malabsorption syndromes familial various medication (oral [aci.health.nsw.gov.au]

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Cystitis

Our findings indicate that the inhibition of miR-214 promotes the EMT process and contributes to bladder wall fibrosis by up-regulating Mfn2, thus leading to the occurrence [ncbi.nlm.nih.gov]

[…] expression levels of N-cadherin, Fibronectin, Twist1, Snail and Vimentin mRNA and protein decreased, whereas the expression levels of Mfn2, E-cadherin and ZO-1 mRNA and protein increased [ncbi.nlm.nih.gov]

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Constipation

As patients with CF live longer and fuller lives, increasing encumbrances from gastrointestinal manifestations of CF will be observed. [ncbi.nlm.nih.gov]

Foundation Patient Registry (CFFPR) was founded, clinicians have witnessed significant advances in both the quality and quantity of life for patients living with Cystic Fibrosis [ncbi.nlm.nih.gov]

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Liver Fibrosis

Combination of diabetes and non-alcoholic fatty liver disease may increase liver fibrosis risk New research has uncovered that fatty liver and diabetes influence fibrosis. [belmarrahealth.com]

In this cohort study, we investigated whether platelets' increase after entecavir (ETV) therapy was associated with the improvement of liver fibrosis. [ncbi.nlm.nih.gov]

Secondary aims were to assess the diagnostic accuracy of ELF for significant fibrosis and cirrhosis and to determine whether combinations of fibrosis markers increase diagnostic [ncbi.nlm.nih.gov]

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Hypersensitivity

In some populations, family history of pulmonary fibrosis or hypersensitivity pneumonitis may increase the risk of developing hypersensitivity pneumonitis. [nhlbi.nih.gov]

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Gingivitis

Eighteen months after disease onset there was scarring of the penis together with suspected fibrosis of the inflamed gingival region. [ncbi.nlm.nih.gov]

In addition the patient was HLA DQ7(3) positive, a haplotype thought to be increased in patients with cicatricial pemphigoid (CP); LAD with scarring or CP with solely linear [ncbi.nlm.nih.gov]

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Anemia

[…] surgery cirrhosis, which involves scarring of the liver fibrosis, or scar tissue, within the bone marrow hemolysis, which is the rupture of red blood cells that can occur [healthline.com]

Factors that increase red blood cell destruction include: hemorrhage from: endometriosis accidents gastrointestinal lesions menstruation childbirth excessive uterine bleeding [healthline.com]

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Hypertension

[…] left atrial (LA) volume, fibrosis and fat content, reduced LA conduction velocity, and increased AFV and AF duration. 33, 35 A unique AF substrate is seen with sustained [doi.org]

[…] vascular dysfunction, cardiac fibrosis, and increased risk of myocardial infarction and stroke. 31 Chronic treatment of hypertensive rats with mineralocorticoid receptor [doi.org]

AF), increased left ventricular hypertrophy (LVH) and diastolic dysfunction, increased stiffness of large arteries, widespread tissue fibrosis, increased remodeling of resistance [doi.org]

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Sinusitis

increased IgG4 plasma cells. [ncbi.nlm.nih.gov]

Cystic fibrosis has a genetic defect and increased mucin, which are potential treatment targets with dornase alfa showing efficacy. [mdpi.com]

Although initial concern was greatest for malignancy, a biopsy specimen confirmed the presence of a dense lymphoplasmacytic infiltrate and storiform fibrosis, associated with [ncbi.nlm.nih.gov]

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Essential Hypertension

Over time, fibrosis may occur, further contributing to the poor compliance of the ventricle. [emedicine.medscape.com]

As the left ventricle does not relax during early diastole, left ventricular end-diastolic pressure increases, further increasing left atrial pressure in late diastole. [emedicine.medscape.com]

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Alcohol Abuse

Studies show alcohol use can affect these parts of the body: High blood pressure, irregular heartbeat, stroke Inflammation, including alcoholic hepatitis, fibrosis, cirrhosis [gatewayfoundation.org]

Acute kidney failure and chronic kidney disease Inflammation and swelling of blood vessels that prevent proper digestion Increased susceptibility to diseases such as tuberculosis [gatewayfoundation.org]

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Tonsillitis

Multiple mechanisms may be responsible for this syndrome, including (1) impaired endothelial dysfunction, [9] (2) increased release of local vasoconstrictors, (3) fibrosis [emedicine.medscape.com]

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Malnutrition

Chronic diseases may be associated with nutrient loss, increased nutrient demand, and/or malabsorption. [labtestsonline.org]

[…] the body's demand for energy Examples of these types of conditions include childhood cancers, congenital heart disease, cystic fibrosis and cerebral palsy. [nhs.uk]

An increased loss of nutrients may be seen with chronic kidney disease, diarrhea and excessive bleeding. [labtestsonline.org]

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Acute Respiratory Infection

It is further mentioned that along with another cytokine, TGF-β1 increases fibrosis and scarring around tuberculous lesion leading to reduced function of the lung parenchyma [lungindia.com]

These results suggest that TGF-β1 level is most dominant in patients with extensive fibrosis lesion of the lung. [lungindia.com]

Moreover, the mean plasma level of TGF-β1 was significantly increased in the group with extensive lesion compared with the group with minimal lesion. [lungindia.com]

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Metabolic Syndrome

We found increased levels of HbA1c (p 0.054) and HOMA-IR (0.001) in the group with NAFLD as well. [dx.doi.org]

Ghorbel, Relation entre stéatose, activité et fibrose au cours de l’hépatite chronique C Relationship between steatosis, inflammation and fibrosis in chronic hepatitis C, [doi.org]

Ballestri et al. evaluated obese patients using ultrasonography and found a relationship between HOMA-IR and insulin in patients with NAFLD, except in individuals with fibrosis [dx.doi.org]

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Urinary Stress Incontinence

following radiation therapy, significant fibrosis from prior vaginal surgery, severe atrophy) are at increased risk for complications following synthetic mesh placement [auanet.org]

Compromised tissue may heal poorly, thereby increasing the risk for complications when mesh is placed. [auanet.org]

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Esophagitis

Subepithelial fibrosis and increased expression of transforming growth factor B (TGF-B) are also observed. [globalgenes.org]

Often starting in childhood with eating difficulties and symptoms of gastroesophageal reflux disease, it progresses with increasing inflammation, fibrosis, and strictures [mdedge.com]

Abstract Eosinophilic esophagitis (EoE) is rare but incidence and prevalence is increasing. [ncbi.nlm.nih.gov]

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Insulin Resistance

[…] with advancing stage of fibrosis. [ncbi.nlm.nih.gov]

More advanced fibrosis is accompanied by increased TNF-α expression [ 38 ]. [dx.doi.org]

Ghorbel, Relation entre stéatose, activité et fibrose au cours de l’hépatite chronique C Relationship between steatosis, inflammation and fibrosis in chronic hepatitis C, [doi.org]

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Food Allergy

Conditions that increase the permeability of the small intestinal mucosa to proteins such as viral gastroenteritis, premature birth, and cystic fibrosis also seem to increase [farrp.unl.edu]

[…] levels of subepithelial fibrosis and increased expression of TGF-b1 and its signaling molecule phospho-SMAD2/3 compared with patients with GERD and normal subjects. [dx.doi.org]

All seven EoE patients demonstrated subepithelial fibrosis (4 severe, 3 moderate) on trichrome staining. [dx.doi.org]

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Hyperuricemia

[…] and increased reactive oxygen radicals.( 3 - 6 ) Hyperuricemia and secondary (saturnine) gout are common findings associated with chronic lead toxicity and they are thought [archivesofrheumatology.org]

Both factors are well-known related to progression of kidney disease.2 Epidemiological studies have recently shown the association between serum uric acid levels and increased [revistanefrologia.com]

[…] rheumatic entity due to chronic lead toxicity.( 3 ) Previous studies have established that lead exposure causes renal dysfunction via direct tubular damage, tubulointerstitial fibrosis [archivesofrheumatology.org]

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