Finely Wrinkled Palms: Causes & Reasons

Possible Causes for Finely Wrinkled Palms

Ehlers-Danlos Syndrome Spondylodysplastic Type 3

Clinical features include postnatal growth retardation, moderate short stature, protuberant eyes with bluish sclerae, hands with finely wrinkled palms, atrophy of the thenar [uniprot.org]

wrinkled palms, and characteristic radiologic features ({2:Giunta et al., 2008}). [diseaseinfosearch.org]

Overview Ehlers-Danlos syndrome spondylodysplastic type 3 is characterized by short stature, hyperelastic skin and hypermobile joints, protuberant eyes with bluish sclerae, finely [diseaseinfosearch.org]

Laron Syndrome with Immunodeficiency

Clinical features included postnatal growth retardation, moderate short stature, protuberant eyes with bluish sclerae, hands with finely wrinkled palms, atrophy of the thenar [findzebra.com]

wrinkled palms; Prominent veins; Cigarette-paper scars; Delayed wound healing MUSCLE, SOFT TISSUE: Thenar muscle atrophy; Hypothenar muscle atrophy LABORATORY ABNORMALITIES [findzebra.com]

wrinkled palms; Thenar muscle atrophy; Hypothenar muscle atrophy; Inability to adduct thumbs; Short metacarpals; Short phalanges; Widened metaphyses (metacarpal and phalanges [findzebra.com]

Ehlers-Danlos Syndrome Classic-Like Type 2

wrinkled palms, atrophy of the thenar muscles, and tapering fingers. [nature.com]

[…] characterized by hyperextensible thin skin, easy bruising, hypermobility of the small joints with a tendency to contractures, protuberant eyes with bluish sclerae, hands with finely [nature.com]

Ehlers-Danlos Syndrome Cardiac-Valvular Type

wrinkled palms Thenar atrophy Tapering fingers Musculocontractural EDS Mutations of CHST14 gene coding for carbohydrate sulfotransferase 14 (dermatan 4-O-sulfotransferase [ganfyd.org]

wrinkled palms, atrophy of the thenar muscles, and tapering fingers. [nature.com]

SLC39A13 gene at 11p11.2 that codes for Zinc transporter ZIP13 Skeletal dysplasia Skin hyperelasticity Joint hypermobility Protuberant eyes with bluish sclerae Abnormal hands Finely [ganfyd.org]

Platyspondyly

Clinical features included postnatal growth retardation, moderate short stature, protuberant eyes with bluish sclerae, hands with finely wrinkled palms, atrophy of the thenar [findzebra.com]

wrinkled palms, and characteristic radiologic features (Giunta et al., 2008). [ncbi.nlm.nih.gov]

wrinkled palms; Prominent veins; Cigarette-paper scars; Delayed wound healing MUSCLE, SOFT TISSUE: Thenar muscle atrophy; Hypothenar muscle atrophy LABORATORY ABNORMALITIES [findzebra.com]

Ehlers-Danlos Syndrome

Clinical features include postnatal growth retardation, moderate short stature, protuberant eyes with bluish sclerae, hands with finely wrinkled palms, atrophy of the thenar [uniprot.org]

wrinkled palms, and characteristic radiologic features (Giunta et al., 2008; pubmed:18513683). [flybase.org]

wrinkled palms, atrophy of the thenar muscles, and tapering fingers. [nature.com]

Blegvad-Haxthausen Syndrome

Fine, diffused wrinkling Till date, there is no known cure for this disease. If the number of lesions is limited the doctor may look at surgical excision as an option. [lybrate.com]

These lesions rarely occur on the neck, face, palms and soles. They may be isolated to grouped together to give a patchy appearance. 1. Atrophic papules 2. [lybrate.com]

Ehlers-Danlos Syndrome Musculocontractural Type 2

wrinkled palms Thenar atrophy Tapering fingers Musculocontractural EDS Mutations of CHST14 gene coding for carbohydrate sulfotransferase 14 (dermatan 4-O-sulfotransferase [ganfyd.org]

SLC39A13 gene at 11p11.2 that codes for Zinc transporter ZIP13 Skeletal dysplasia Skin hyperelasticity Joint hypermobility Protuberant eyes with bluish sclerae Abnormal hands Finely [ganfyd.org]

Dermatosparaxis

wrinkled palms Atrophy of the thenar muscles, and tapering fingers Hypermobility of distal joints Characteristic radiologic findings Minimal criteria suggestive for spondylodysplastic [wikimsk.org]

wrinkled palms short stature (progressive in childhood), bowing of limbs, pes planus, osteopenia, (characteristic X-ray findings of) skeletal dysplasia, JH B4GALT7: radioulnar [mdpi.com]

[…] multiple spontaneous fractures Ascending aortic aneurysm Lung hypoplasia, restrictive lung Gene specific criteria (SLC39A13) Protuberant eyes with bluish sclerae Hands with finely [wikimsk.org]

Ehlers-Danlos Syndrome Type 4

wrinkled palms, atrophy of the thenar muscles, and tapering fingers. [nature.com]

Ehlers-Danlos-Syndrome Type 10

wrinkled palms, atrophy of the thenar muscles, and tapering fingers. [nature.com]

Ehlers-Danlos Syndrom Classic Type 2

wrinkled palms, atrophy of the thenar muscles, and tapering fingers. [nature.com]

Fetus Papyraceous

wrinkled palms, atrophy of the thenar muscles, and tapering fingers. [nature.com]

Blue Sclera

wrinkled palms, and characteristic radiologic features (Giunta et al., 2008). [ncbi.nlm.nih.gov]

Syndrome Ehlers-Danlos syndrome spondylodysplastic type 3 is characterized by short stature, hyperelastic skin and hypermobile joints, protuberant eyes with bluish sclerae, finely [ncbi.nlm.nih.gov]

Hidrotic Ectodermal Dysplasia

Periorbital skin was wrinkled with hyperpigmentation. Skin in general was thin, dry, pale and finely wrinkled. [ijdvl.com]

Palm, sole and nails were normal. External genitalia, nipples and mental development were normal. Other systemic examination including CNS were normal. [ijdvl.com]

Ichthyosis Vulgaris

In IV the palms and soles have more noticeable creases and wrinkles of the skin. Eczema may also develop in acquired ichthyosis and IV, making the skin itchy and red. [ichthyosis.org.uk]

The skin is seen to be dry and flaky with the build-up of fine, pale scales in certain areas, usually the outer parts of arms, lower legs and across the abdomen. [ichthyosis.org.uk]

Limb-Girdle Muscular Dystrophy Type 1G