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1,646 Possible Causes for Flat Affect, Pseudoepiphyses of the Metacarpals, Round Face in Infancy

  • Autism

    Her clinical features included hypotonia and feeding difficulties during infancy, coarse face with notably prominent forehead, prominent eyebrows, broad flat nasal bridge[ncbi.nlm.nih.gov] […] and round cheeks, small hands and feet with bilateral brachymetaphalangism, proximal implantation of the thumbs and short toenails, mild mental retardation and autistic behaviour[ncbi.nlm.nih.gov]

    Missing: Pseudoepiphyses of the Metacarpals
  • Endogenous Depression

    Abstract We assessed the 8:00 AM ratio of free cortisol/18-hydroxy-11-deoxycorticosterone (18-OH-DOC) in 56 endogenous depressive inpatients and in 22 normal volunteers. A ratio higher than 40 was associated with a diagnostic sensitivity for endogenous depression of 75%, a specificity of 95.5%, and a diagnostic[…][ncbi.nlm.nih.gov]

    Missing: Pseudoepiphyses of the Metacarpals Round Face in Infancy
  • Stroke

    Post-stroke emotional difficulties include anxiety, panic attacks, flat affect (failure to express emotions), mania, apathy and psychosis.[en.wikipedia.org] […] lip swelling or ulceration • Rhinoscleroma initially affects the nasal mucosa but may spread slowly to the upper lip, producing plaques or nodules with sunken centres. •[slideshare.net] . • In secondary syphilis, moist, flat, papulonodular lesions (condylomata lata) often appear at the mucocutaneous junctions and commissures. • TB or leprosy may cause chronic[slideshare.net]

    Missing: Pseudoepiphyses of the Metacarpals Round Face in Infancy
  • Brain Concussion

    A brain concussion is a still incompletely defined syndrome of traumatic brain injury (TBI) that causes a spectrum of symptoms without evident structural damage to the brain. A headache, cognitive deficits, emotional instability, sleep disturbances, and an overall change in mental state after trauma are highly[…][symptoma.com]

    Missing: Pseudoepiphyses of the Metacarpals Round Face in Infancy
  • Wolf-Hirschhorn Syndrome

    Microcephaly Round, moonlike face Wide-set, downward-slanting eyes Strabismus Epicanthal folds Williams syndrome Type of abnormality: deletion Critical region: 7q11.23 Mental[alpfmedical.info] Most individuals affected by this disorder have distinctive facial features, such as a broad, flat nasal bridge and a high forehead described as the “Greek warrior helmet”[medcraveonline.com] Note the round face with full cheeks, hypertelorism, epicanthal folds, and apparently low-set ears. Child with cri-du-chat syndrome.[emedicine.medscape.com]

  • Psychosis

    (i.e., flat affect, lack of initiative) rare deterioration of the patients' personality absence of psychosis in the patient's family absence of premorbid schizoid traits[epilepsy.com] Symptoms may include bizarre delusions, prominent hallucinations, incoherence, flat affect, avolition, and anhedonia.[dualdiagnosis.org] Mood disturbances, including euphoria, irritability, and labile or flat affect, have often accompanied psychotic symptoms in these patients.[acnp.org]

    Missing: Pseudoepiphyses of the Metacarpals Round Face in Infancy
  • Schizophrenia

    affect and cognitive slowness.[reddit.com] Symptoms include: “Flat affect” (reduced expression of emotions via facial expression or voice tone) Reduced feelings of pleasure in everyday life Difficulty beginning and[web.archive.org] Negative symptoms are the tendency toward restricted emotions, flat affect (diminished emotional expressiveness), and the inability to start or continue productive activity[drugs.com]

    Missing: Pseudoepiphyses of the Metacarpals Round Face in Infancy
  • XXXXY Syndrome

    face in infancy,(Look very much like a cherub) coarse features in older age, hypertelorism, epicanthal folds, prognathism, gynecomastia (rare), congenital heart defects ([web.archive.org] Affected individuals have distinctive facial features that can include widely spaced eyes ( ocular hypertelorism ), outside corners of the eyes that point upward ( upslanting[ghr.nlm.nih.gov] Other features include severely impaired speech, behavioral problems, short or broad neck, low birth weight, hyperextensible joints, short stature, round face in infancy,[web.archive.org]

    Missing: Pseudoepiphyses of the Metacarpals
  • Cleidocranial Dysplasia

    […] the metacarpals, and dental anomalies including delayed eruption of permanent dentition and multiple supernumerary teeth.[ncbi.nlm.nih.gov] The dental manifestations may affect articulation and mastication.[orpha.net] […] of metacarpal and metatarsal bones ; dysplasia of the middle phalanx of the fifth finger ; shortening of the distal phalanges; thick epiphyseal ossification centers; retarted[mirc.luriechildrens.org]

    Missing: Round Face in Infancy
  • Spondylo-Megaepiphyseal-Metaphyseal Dysplasia

    […] at all metacarpals and phalanges.[ncbi.nlm.nih.gov] Affected individuals may also have Pierre-Robin sequence, an assortment of abnormalities that may occur as a distinct syndrome or as part of another underlying disorder.[rarediseases.org] […] vertebral bodies with sagittal and coronal clefts, missing ossification of the pubic bones, large round "balloon-like" epiphyses of the long bones, and presence of multiple pseudoepiphyses[ncbi.nlm.nih.gov]

    Missing: Round Face in Infancy