Flattened Nasal Bridge: Causes & Reasons

Possible Causes for Flattened Nasal Bridge

The facial trait include large head with prominent forehead, rounded eyebrows, flattened nasal bridge, macroglossia, widely spaced teeth, and prognathism. [ncbi.nlm.nih.gov]

The facial dysmorphism is marked by a large head with a prominent forehead, rounded eyebrows, a flattened nasal bridge, macroglossia, widely spaced teeth, and prognathism. [orpha.net]

Additional features include large head with prominent forehead, rounded eyebrows, flattened nasal bridge, macroglossia, widely spaced teeth, dysostosis multiplex, and motor [diseaseinfosearch.org]

Spondyloepimetaphyseal Dysplasia Type SPONASTRIME

bridge Depressed bridge of nose Flat bridge of nose Flat nasal bridge Flat, nasal bridge Flattened nasal bridge Low nasal bridge Low nasal root [ more ] 0005280 Frontal bossing [rarediseases.info.nih.gov]

0002007 Lumbar hyperlordosis Excessive inward curvature of lower spine 0002938 Malar flattening Zygomatic flattening 0000272 Mesomelia Disproportionately short middle portion [rarediseases.info.nih.gov]

Upturned nasal tip Upturned nose Upturned nostrils [ more ] 0000463 Delayed skeletal maturation Delayed bone maturation Delayed skeletal development [ more ] 0002750 Depressed nasal [rarediseases.info.nih.gov]

Marshall-Smith Syndrome

bridge Depressed bridge of nose Flat bridge of nose Flat nasal bridge Flat, nasal bridge Flattened nasal bridge Low nasal bridge Low nasal root [ more ] 0005280 Distal widening [rarediseases.info.nih.gov]

[…] nasal cavity 0000452 Death in childhood 0003819 Decreased body weight Decreased weight Low body weight Low weight Weight less than 3rd percentile [ more ] 0004325 Depressed nasal [rarediseases.info.nih.gov]

Mucopolysaccharidosis Type 1 H/S

Physical Characteristics : Short stature Halted growth Low, flattened nasal bridge Thick coarse facial features Cloudy corneas Abnormal bones in the spine Deafness Enlarged [smartspeechtherapy.com]

The nose can have a flattened nasal bridge with continuous nasal discharge. The eye sockets may be widely spaced, and the eyes may protrude from the skull. [en.wikipedia.org]

Distinct facial features (including flat face, depressed nasal bridge, and bulging forehead) become more evident in the second year. [smartspeechtherapy.com]

Stickler Syndrome Type 2

The middle of the face and nasal bridge typically appear flattened, and some patients have a cleft palate (a hole in the roof of the mouth), which can be corrected by surgery [medschool.lsuhsc.edu]

Craniofacial involvement includes maxillary hypoplasia, flattening or wid- ening of the nasal bridge, micro/retrognathia, and palatal abnormalities such as highly arched palate [nature.com]

Mucopolysaccharidosis Type 1 H

The nose can have a flattened nasal bridge with continuous nasal discharge. The eye sockets may be widely spaced, and the eyes may protrude from the skull. [en.wikipedia.org]

Distinct facial features (including flat face, depressed nasal bridge, and bulging forehead) become more evident in the second year. [smartspeechtherapy.com]

Achondroplasia

nasal bridge crowded or misaligned teeth curved lower spine — a condition also called lordosis (or sway-back), which may lead to kyphosis, or the development of a small hump [childrenshospital.org]

nasal bridge Crowded or misaligned teeth Curved lower spine (a condition also called lordosis [or "sway-back"] which may lead to kyphosis, or the development of a small hump [stanfordchildrens.org]

nasal bridge Crowded or misaligned teeth Curved lower spine (lordosis or "sway-back") which may lead to kyphosis (hunchbacK), the development of a small hump near the shoulders [chop.edu]

Spondyloepiphyseal Dysplasia Type Cantú

[…] vertebral bodies 0004634 Curly eyelashes 0007665 Curly hair 0002212 Delayed skeletal maturation Delayed bone maturation Delayed skeletal development [ more ] 0002750 Depressed nasal [rarediseases.info.nih.gov]

Moebius Syndrome

0002312 Congenital fibrosis of extraocular muscles 0001491 Cranial nerve VI palsy 0006897 Decreased testicular size Small testes Small testis [ more ] 0008734 Depressed nasal [rarediseases.info.nih.gov]

Rhizomelic Chondrodysplasia Punctata Type 1

nasal bridge and bulbous nose, withflattened face appearance. [rb.org.br]

This condition is also associated with distinctive facial features, particularly a flattened-appearing nose with crescent-shaped nostrils and a flat nasal bridge. [ghr.nlm.nih.gov]

Microcephaly - Chorioretinopathy - Lymphedema - Mental Retardation

nasal bridge broad, large nasal tip Head And Neck Head: flat occiput microcephaly (-6 s.d.) [malacards.org]

[…] more ] 0000455 Cataract Clouding of the lens of the eye Cloudy lens [ more ] 0000518 Chorioretinal dysplasia 0007731 Corneal opacity 0007957 Deep philtrum 0002002 Depressed nasal [rarediseases.info.nih.gov]

Setleis Syndrome

nasal bridge, a bulbous nose, clefting of the chin, absent Meibomian glands, wrinkled facial skin, and a low frontal hairline. [symptoma.com]

[…] of the nasal bridge with a bulbous nasal tip; (6) increased mobility of the skin, associated with severely redundant facial soft tissue; and (7) normal growth and development [jamanetwork.com]

[…] abnormalities are: absence of eyelashes on both lids, leonine-like facies, multiple rows of eyelashes on the upper lids (termed distichiasis), sparse and slanted eyebrows, a flattened [symptoma.com]

Donnai-Barrow Syndrome

Depressed bridge of nose, Depressed nasal root/bridge, Depressed nasal root, Flat nasal root, Low nasal bridge, Flattened nasal bridge [more] Posterior positioning of the [rarediseases.oscar.ncsu.edu]

This disorder is characterized by unusual facial features, including prominent, wide-set eyes with outer corners that point downward; a short bulbous nose with a flat nasal [medlineplus.gov]

nasal bridge; ears that are rotated backward; and a widow's peak hairline.[3] Individuals with Donnai–Barrow syndrome have severe hearing loss caused by abnormalities of [en.wikipedia.org]

Larsen's Syndrome

Bilateral dislocation of the knees, pes cavus, cylindrically shaped fingers, and characteristic facies (wide-spaced eyes, flattened nasal bridge and prominent forehead) were [ibis-birthdefects.org]

nasal bridge hypertelorism prominent forehead hands long cylindrical fingers that do not taper wide distal phalanx at the thumb elbows bilateral radial head dislocations [orthobullets.com]

Pseudopseudohypoparathyroidism

Round face with low flattened nasal bridge Bony changes in hands and feet involving: Short bones in fingers and toes giving short stubby hands and feet (Fig 1) Short bones [hypopara.org.uk]

[…] eruption of teeth Delayed eruption Delayed teeth eruption Delayed tooth eruption Eruption, delayed Late eruption of teeth Late tooth eruption [ more ] 0000684 Depressed nasal [rarediseases.info.nih.gov]

Pseudohypoparathyroidism Type 1A

AHO is characterized by short stature, obesity, round face with flat nasal bridge, brachydactyly, subcutaneous ossification and possible / variable developmental delay. [hopkinsmedicine.org]

Recombinant Chromosome 8 Syndrome

[…] finger 0100490 Chronic otitis media Chronic infections of the middle ear 0000389 Clinodactyly of the 5th finger Permanent curving of the pinkie finger 0004209 Depressed nasal [rarediseases.info.nih.gov]

Rhizomelic Chondrodysplasia Punctata Type 2

nasal bridge and bulbous nose, withflattened face appearance. [rb.org.br]

Most individuals with CDPX2 have a flattened nasal bridge and frontal bossing. [ncbi.nlm.nih.gov]

[…] auditiveand visual dificiencies, seizures, optic nerves hypoplasia,kyphoscoliosis and cleft spine (2,5,12,13) .Patients usually present facies with micrognathia, malarhypoplasia, flattened [rb.org.br]

Langer Nishino Yamaguchi Syndrome

HPO ID Percent of people who have these symptoms is not available through HPO Blepharophimosis Narrow opening between the eyelids 0000581 Cutis marmorata 0000965 Depressed nasal [rarepediatricsnews.com]

Camptodactyly Syndrome Guadalajara Type 1

[…] or toes 0001156 Cubitus valgus Outward turned elbows 0002967 Delayed skeletal maturation Delayed bone maturation Delayed skeletal development [ more ] 0002750 Depressed nasal [rarediseases.info.nih.gov]

Kniest Dysplasia

A: A dysmorphic face with hypertelorism and a flattened nasal bridge. B, C: Short stature. [raredisorders.imedpub.com]

INHERITANCE: AD FREQUENCY: rare CLINICAL: round flat face, depressed nasal bridge, prominant eyes, cleft palate, clubfoot,inguinal herniae, myopia and hearing loss, retinal [orthopaedicsone.com]

Monosomy 9p

Many affected infants also have unusually flat midfacial regions (midfacial hypoplasia), including a short nose, flattened nasal bridge, and upturned nostrils (anteverted [rarediseases.org]

nasal bridge with anteverted nostrils and long philtrum, micrognathia, choanal atresia, short neck), single umbilical artery, omphalocele, inguinal or umbilical hernia, genital [orpha.net]

nasal bridge; anteverted nostrils; and long philtrum (Alfi et al. 1973 Alfi O Donnell GN Crandall BF Derencsenyi A Menon R Deletion of the short arm of chromosome 9 (46, [cell.com]

Perinatal Lethal Gaucher Disease

[…] tip, upturned Upturned nasal tip Upturned nose Upturned nostrils [ more ] 0000463 Depressed nasal bridge Depressed bridge of nose Flat bridge of nose Flat nasal bridge Flat [rarediseases.info.nih.gov]

nasal bridge Flattened nasal bridge Low nasal bridge Low nasal root [ more ] 0005280 Ectropion Eyelid turned out 0000656 Fetal akinesia sequence 0001989 Hepatomegaly Enlarged [rarediseases.info.nih.gov]

Pancytopenia Low blood cell count 0001876 Stillbirth Stillborn 0003826 Thrombocytopenia Low platelet count 0001873 30%-79% of people have these symptoms Anteverted nares Nasal [rarediseases.info.nih.gov]

Williams-Beuren Syndrome

nasal bridge with small upturned nose Long ridges in the skin that run from the nose to the upper lip (philtrum) Prominent lips with an open mouth Skin that covers the inner [web.archive.org]

These may exhibit as a flattened nasal bridge with small upturned nose, skin that covers the inner corner of the eye (called epicanthal folds) and prominent lips with an open [questia.com]

nasal bridge with small upturned nose Long ridges in the skin that run from the nose to the upper lip Prominent lips with an open mouth Skin that covers the inner corner [nlm.nih.gov]

Atelosteogenesis

bridge ; Dumbbell-shaped femur ; Flat acetabular roof ; Horizontal sacrum ; Lumbar hyperlordosis ; Malar flattening ; Micrognathia ; Micromelia ; Midface retrusion ; Platyspondyly [mousephenotype.org]

Monosomy 1p36 Syndrome

nasal bridge midface hypoplasia deep-set eyes prominent forehead and chin epicanthic folds low set ears neurological abnormalities developmental delay and intellectual disability [radiopaedia.org]

nasal bridge 2 4 9 15 17 and midface hypoplasia 6 8 13 were also frequent. [jmg.bmj.com]

Kanzaki Disease

30%-79% of people have these symptoms Cardiomegaly Enlarged heart Increased heart size [ more ] 0001640 Coarse facial features Coarse facial appearance 0000280 Depressed nasal [rarediseases.info.nih.gov]

Cleidocranial Dysplasia

He had a patent anterior fontanelle, prominent forehead, flattened nasal bridge and eyes set widely apart. [scielo.org.za]

Extraoral examination revealed hypertelorism (increased intercanthal distance of eyes), frontal bossing with brachycephalic skull, depressed and flattened nasal bridge, malar [jnsbm.org]

Acrodysostosis Type 1

bridge - Cone epiphyses / epiphysis - Depressed nasal bridge - Flattened nose - Hypoplastic maxillary bones / zygomatic bones / maxillary hypoplasia - Intellectual deficit [csbg.cnb.csic.es]

[…] bone, with an unusually small nose and the bridge of the nose appearing flattened a rounded nose tip with nostrils pointing upward, giving the appearance of an upturned nose [acrodysostosis.org]

IMAGE Syndrome

In brief, they presented with severe intrauterine growth restriction, frontal bossing, and a flattened nasal bridge. [ncbi.nlm.nih.gov]

Some affected individuals have distinctive facial features, such as a prominent forehead, low-set ears, and a short nose with a flat nasal bridge. [ghr.nlm.nih.gov]