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75 Possible Causes for Flattened T Wave, Torsades De Pointes

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  • Hypokalemia

    […] than the T wave. flattening of the T wave.[] In addition, it reiterates the importance of repeated history taking in a patient with undiagnosed hypokalemia and torsade de pointes which avoided a device therapy. 2013[] BACKGROUND: Our primary objective was to determine the adjusted quantitative associations of clinical predictors with QT prolongation, a defining cause of Torsades de Pointes[]

  • Quinidine

    T waves (without dysrhythmia), have occurred frequently and hypotension and ventricular tachycardia have occurred occasionally in patients receiving IV quinidine gluconate[] He developed torsades de pointes and subsequently cardiac arrest.[] de pointes type.[]

  • Electrolyte Imbalance

    Clinical signs of hyperkalaemia include muscle weakness, hypotension , bradycardia and loss of cardiac output, and ECG changes may include peaked T waves and flattened P waves[] Ventricular tachycardia, ventricular fibrillation and torsade de pointes.[] Hypokalaemia may cause acquired long QT syndrome (LQTS) and predisposes to torsade de pointes ( polymorphic ventricular tachycardia ).[]

  • Phenothiazine

    Abstract A patient with schizophrenia developed torsade de pointes, a life-threatening cardiac arrhythmia, due to administration of phenothiazines.[] Minor QT prolongation but no Torsades de pointes has been reported since thiorodiazine was taken off the market. Isbister GK.[]

  • Digitalis Toxicity

    Electrocardiographic signs of digitalis toxicity include first-degree atrioventricular (A-V) block with depressed S-T segments, shortened Q-T intervals, and flattened T waves[] de pointes Sinus or AF bradycardias Classically see tachy/brady with VT bradycardia unresponsive to atropine Treatment Stop digoxin![] de pointes. 11 References Braunwald E.[]

  • Long QT Syndrome

    The other reasons are compounding factors such as heart rate, presence of U-waves, and flattened T-waves. 5 Drug-induced torsades de pointes is a significant cause of morbidity[] Prolonged QT interval may be associated with torsades de pointes and lead to sudden cardiac death.[] , the T wave is flattened or when notching of the T wave occurs.[]

  • Adrenal Insufficiency

    If potassium is above 7.0 mmol/L and hyperkalaemic ECG changes are present (eg. peaked T waves wide QRS complex flattened P waves), treat with either of the following: give[] However, reports on adrenal insufficiency in which the QT interval was sufficiently prolonged to cause Torsades de Pointes are rare.[] Abstract QT prolongation and Torsades de Pointes were observed in a 44-year-old woman who had adrenal insufficiency caused by isolated adrenocorticotropic hormone deficiency[]

  • Lithium Toxicity

    Cardiovascular side effects are usually mild and manifest as nonspecific ECG changes, such as ST-T flattening and T-wave inversion.[] The most common electrocardiographic finding is T-wave flattening.[] However, in severe overdose, QT prolongation and tachyarrhythmias such as torsade de pointes have been reported.[]

  • Thioridazine

    As with other phenothiazines, benign repolarization changes such as prolongation of the Q-T interval, flattening of the T wave and the appearance of a U wave have been reported[] ADR Inferred Reduced CYP2D6 activity associated with Torsades de pointes and/or sudden death.[] There are several published case reports of Torsades de pointes and sudden death associated with thioridazine treatment.[]

  • Tricyclic Antidepressant Overdose

    The patient’s EKG shows a widening of the QRS resulting in a wide QT interval with T wave inversion and/or flattening in various leads.[] Torsade de pointes occurs uncommonly.[] Doxepin-induced torsade de pointes tachycardia. Ann Intern Med 2001; 135: 384–5 PubMed Google Scholar 43. Davison ET.[]

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