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400 Possible Causes for Flattening of the Talar Dome, Mutation in the PHEX Gene, Rib Tenderness

  • X-Linked Hypophosphatemia

    […] shortening of the talar neck and flattening of the talar dome.[ncbi.nlm.nih.gov] To date, 131 mutations in the PHEX gene have been reported.[ncbi.nlm.nih.gov] Gene mutations in PHEX prevent it from correctly regulating fibroblast growth factor 23.[en.wikipedia.org]

  • Familial Hypophosphatemia

    X-linked dominant hypophosphatemic rickets, due to mutations in the PHEX gene, is the most common inherited form of the disorder.[genedx.com] Since, the gene mutation occurs on the X chromosome, it is called an X-linked disorder Familial Hypophosphatemia is caused by a mutation in the PHEX gene, leading to defective[dovemed.com] Mutated in X-Linked Dominant Hypophosphatemic Rickets Genome Research 7 573-585 (1997) Dixon, PH et al., Mutational Analysis of PHEX Gene in X-linked Hypophosphatemia J Clin[genedx.com]

    Missing: Flattening of the Talar Dome
  • Vitamin D Deficiency

    In this study, we looked for vitamin D deficiency in patients with flank pain associated with tenderness over the tips of the lowermost ribs.[ncbi.nlm.nih.gov] […] in the PHEX gene.[ncbi.nlm.nih.gov] Bones can feel painful to moderate pressure (often more noticeable in the ribs or shin bones).[patient.info]

    Missing: Flattening of the Talar Dome
  • Osteomalacia

    The first noticeable signs of osteomalacia are: bone pain in the thigh or the lower back that extends to the ribs and to the arms, and bone tenderness.[medicalterms.info] There is no correlation between the severity of the disease and the type or localization of PHEX gene mutations (48).[scielo.br] There is tenderness on percussion of bones, especially over the tibial shins.[boneandspine.com]

    Missing: Flattening of the Talar Dome
  • Hypophosphatemia

    […] of tenderness to palpation over the bilateral, anterior chest wall, specifically over the nipple lines and intercostal spaces of the 6th to 8th ribs.[karger.com] Etiology The disease is caused by various mutations in the PHEX gene (Xp22.1) and is transmitted as an X-linked dominant trait with complete penetrance, but variable expressivity[orpha.net] The following summer, he developed left sided chest pain while he was swimming and was subsequently found to have a fracture of left sixth rib with physical exam findings[karger.com]

    Missing: Flattening of the Talar Dome
  • Rib Fracture

    Imaging: Chest Precaution Rib Fracture is a clinical diagnosis based on injury mechanism and exam (e.g. focal, exquisite rib tenderness) Imaging can confirm Rib Fracture,[fpnotebook.com] Signs Focal point tenderness over rib Referred pain along rib course Bony crepitus over Fracture Ecchymosis , abrasions or swelling over Rib Fracture Complication findings[fpnotebook.com] Tenderness when feeling the rib involved (although this may be hard to locate).[sportsinjuryclinic.net]

    Missing: Flattening of the Talar Dome Mutation in the PHEX Gene
  • Chest Trauma

    […] or rib 'crunching' indicating rib fractures Feel for subcutaneous emphysema Listen Listen for normal, equal breath sounds on both sides.[trauma.org] Clavicular tenderness is not included as “chest wall tenderness.”[mdcalc.com] Pain and tenderness may occur over the rib, sternum and clavicle fractures. Isolated chest trauma resulting from blunt trauma is very rare.[intechopen.com]

    Missing: Flattening of the Talar Dome Mutation in the PHEX Gene
  • Bronchogenic Carcinoma

    Metastasis of bronchogenic carcinoma to the chest wall and axillary lymphnodes is a rare occurrence. This study reports the case of a patient presenting with chest wall swelling as initial symptom which on evaluation was found to be a lymphnode metastasis. The patient also had axillary lymphnode metastasis on the[…][ncbi.nlm.nih.gov]

    Missing: Flattening of the Talar Dome Mutation in the PHEX Gene
  • Pathological Fracture

    BMJ Case Rep. 2012 Nov 21;2012. pii: bcr2012007453. doi: 10.1136/bcr-2012-007453. Author information 1 Department of Trauma & Orthopaedics, St Vincent's University Hospital, Dublin, Ireland. cmurphy@rcsi.ie Abstract Pathological fracture is not uncommon in musculoskeletal oncological surgical practice. When complicated by[…][ncbi.nlm.nih.gov]

    Missing: Flattening of the Talar Dome Mutation in the PHEX Gene
  • Rib Tumor

    The whole side of my rib cage seems to be tender. A cyst has already been ruled out. Should I see a specialist?[healthcentral.com] It was painless and non tender and fixed to the rib anteriorly (Fig 1).[jocr.co.in] I have tenderness in my rib area on the right side (cancer side) but I'm afraid to feel around. I have tenderness in my breast and under my arm, too.[community.breastcancer.org]

    Missing: Flattening of the Talar Dome Mutation in the PHEX Gene