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162 Possible Causes for Flushing, Progressive Polyneuropathy, Pruritus

  • Diabetes Mellitus

    Signs/symptoms of Diabetic Ketoacidosis: [3] Deep, rapid breathing Fruity breath Dry skin and mouth Flushed face Nausea/vomiting Abdominal pain Hypoglycemia : Blood glucose[physio-pedia.com] […] outweighed by the benefits of reducing cardiovascular risk. [ 8 ] Presentation Patients with all types of diabetes may present with polyuria, polydipsia, lethargy, boils, pruritus[patient.info] Acetohexamide* 250 mg once/day–750 mg bid 12–24 h No longer available in US Chlorpropamide * 100 mg once/day–750 mg once/day 24–36 h Chlorpropamide : May cause hyponatremia and flushing[msdmanuals.com]

  • Paraneoplastic Syndrome

    We report a fatal case of severe chronic progressive axonal polyradiculoneuropathy in association with this antibody.[doi.org] Carcinoid tumors produce serotonin degradation products that lead to flushing, diarrhea, and breathing difficulty.[merckmanuals.com] This 59-year-old man developed ophthalmoplegia, dysarthria, dysphagia, pruritus, ataxia, corticobulbar and corticospinal signs in association with prostate cancer.[ncbi.nlm.nih.gov]

  • Chronic Alcoholism

    Flushing Transient flushing is also a common side effect of alcohol, particularly in heavy drinkers. It is due to acetaldehyde, the main breakdown product of alcohol.[dermnetnz.org] Patients may present with jaundice, pruritus, abnormal laboratory findings (eg, thrombocytopenia, hypoalbuminemia, coagulopathy), or complications of portal hypertension,[clevelandclinicmeded.com] ALDH deficiency increases the levels of acetaldehyde formed in the body, leading to facial flushing, tachycardia and nausea.[esciencecentral.org]

  • Anxiety Disorder

    […] may have an increased heart rate, palpitations, profuse perspiration, chest-pain, a choking feeling, lightheadedness, nausea or a churning stomach, shivering chills, hot flushes[bumrungrad.com] The neurological signs are often a progressive spastic paraparesis, cerebellar ataxia, polyneuropathy, and cognitive impairment.[ncbi.nlm.nih.gov] “If you find that every time you have to be around other people your heart rate is accelerating and you feel kind of flushed and nauseous or something like that, then that[rd.com]

  • Multiple Myeloma

    […] to multiple myeloma The initial presentation occasionally is a polyneuropathy when it is part of a POEMS syndrome (mostly the sclerotic form).[radiopaedia.org] Symptoms include fever, chills, arthralgia, myalgia, facial flushing, facial edema, vomiting, weakness, shortness of breath, hypotension, syncope, chest tightness, or angina[investors.amgen.com] Her pruritus resolved, but the lesions persisted. Footnotes Competing interests: None declared. This article has been peer reviewed.[cmaj.ca]

  • Diabetic Polyneuropathy

    In clinical trials, only a few adverse effects have been reported - transient mild headache, flushing, dyspepsia, and some altered color vision.[health.am] […] urinary tract infection, urinary frequency or dribbling, erectile dysfunction, loss of libido, dyspareunia, vaginal dryness, anorgasmia Sudomotor (sweat glands) symptoms: pruritus[aafp.org] Ms Q is a 52-year-old woman who has had progressive polyneuropathy in the setting of diabetes for the past 8 years.[ncbi.nlm.nih.gov]

  • Chronic Inflammatory Demyelinating Polyneuropathy

    Shortly after HSCT the patient developed progressive polyneuropathy of the lower legs and hypoesthesia. Five months later a severe dementia followed.[ncbi.nlm.nih.gov] Other adverse effects include: aseptic meningitis, rigors, myalgias, flushing, fluid overload with edema or congestive heart failure, renal insufficiency (presumably due to[dx.doi.org] […] were local reactions (ie, swelling, redness, heat, pain, and itching at the injection site), headache, diarrhea, fatigue, back pain, nausea, extremity pain, cough, rash, pruritus[prnewswire.com]

  • Diffuse Scleroderma

    […] due to systemic sclerosis Progressive systemic sclerosis Scleredema Scleredema buschkes Scleroderma Scleroderma induced by chemical, including drugs Scleroderma of lung Scleroderma[icd9data.com] […] found in almost half of all patients). 11,12 It manifests as a series of changes in appearance: white or pale as a result of vasospasm, cyanotic from ischemia, then red or flushed[mdedge.com] Skin can breakdown and discharge chalky material (calcium) Salt and pepper dyspigmentation ( hyperpigmentation and hypopigmentation ) Pruritus Rarer cutaneous features Morphoea[dermnetnz.org]

  • Systemic Scleroderma

    […] due to systemic sclerosis Progressive systemic sclerosis Scleredema Scleredema buschkes Scleroderma Scleroderma induced by chemical, including drugs Scleroderma of lung Scleroderma[icd9data.com] […] found in almost half of all patients). 11,12 It manifests as a series of changes in appearance: white or pale as a result of vasospasm, cyanotic from ischemia, then red or flushed[mdedge.com] The steroids help with the pruritus and may lead to some lesional thinning.[clinicaladvisor.com]

  • Fabry Disease

    Agalsidase alfa was generally well tolerated in patients with Fabry disease, with infusion reactions (e.g. rigors, pyrexia, flushing) being the most commonly occurring adverse[ncbi.nlm.nih.gov] Adverse events such as nasopharyngitis, rhinitis, nasal congestion, aggravation of allergic rhinitis with nasal discharge, dyspnea, cough, dizziness, flushing, pruritus, neuralgia[journals.plos.org] […] sensomotor polyneuropathy and oesophagitis after 12 months of treatment.[ncbi.nlm.nih.gov]

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