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29 Possible Causes for Focal Atrophy of Choroid, Glucose Increased

  • Hemochromatosis

    The spectral domain optical coherence tomography showed retinal pigmentary epithelial atrophy associated with irregularities and focal interruption of the ellipsoid zone.[ncbi.nlm.nih.gov] F-FDG PET/CT was performed as routine follow-up and showed a pathological finding of homogeneous increased liver glucose metabolism.[ncbi.nlm.nih.gov] Arthropathy, hepatic fibrosis, glucose intolerance, and increased skin pigmentation are frequent.[orpha.net]

  • Paraneoplastic Syndrome

    D) OCT of the same eye demonstrated neurosensory detachment over the macula with focal areas of RPE atrophy and hypertrophy.[reviewofophthalmology.com] .  CSF: lymphocytosis, raised protein, normal glucose, increased igG (auto antibodies)  Treatment: removal of tumour, immunological treatment 22.[slideshare.net] The case highlights generalized increase in fluoro-deoxy-glucose uptake in the skeletal muscles indicating biopsy proven polymyositis-a paraneoplastic syndrome.[ncbi.nlm.nih.gov]

  • Arteriosclerotic Retinopathy

    Areas of retinal pigment epithelium clump and atrophy (Elschnig spots), forming from the focal acute white retinal pigment epithelium lesions.[emedicine.medscape.com] Alanine Aminotransferase Increased, Arteriosclerotic Retinopathy, Aspartate Aminotransferase Increased, Blood Albumin Decreased, Blood Creatine Increased, Blood Glucose Increased[patientsville.com] There is additional evidence that the risk of cataract increases with increasing diabetes duration and severity of hyperglycemia ( 26 ).[care.diabetesjournals.org]

  • Acute Hypertensive Retinopathy

    Areas of focal chorioretinal atrophy [from previous choroidal infarcts (Elschnig spots)] are a sign of past episodes of acute HTN.[medium.com] A focal area of RPE atrophy was present in the temporal periphery.[westcoastretina.com] Areas of retinal pigment epithelium clump and atrophy (Elschnig spots), forming from the focal acute white retinal pigment epithelium lesions.[emedicine.medscape.com]

  • Retinal Angioma

    MRI revealed evidence of focal cortical atrophy, leptomeningeal enhancement, and right choroid plexus enlargement.[kjophthal.com] HIF1a and HIF2 are potent transcriptional factors that are important for the cellular response under hypoxic conditions, since they enhance glucose uptake and increase expression[eyewiki.aao.org]

  • Febrile Convulsions

    ; both infants had follow-up MRIs showing that hippocampal atrophy had developed.[ncbi.nlm.nih.gov] […] testing should be performed concurrently to increase the sensitivity for detecting bacteria and to determine if there is hypoglycorrhachia characteristic of bacterial meningitis[pediatrics.aappublications.org] These patients demonstrate that prolonged and focal CFCs can occasionally produce acute hippocampal injury that evolves to hippocampal atrophy.[ncbi.nlm.nih.gov]

  • Hypertensive Retinopathy

    Areas of focal chorioretinal atrophy [from previous choroidal infarcts (Elschnig spots)] are a sign of past episodes of acute HTN.[medium.com] Areas of retinal pigment epithelium clump and atrophy (Elschnig spots), forming from the focal acute white retinal pigment epithelium lesions.[emedicine.medscape.com] Increased uric acid and glucose concentrations in vitreous and serum of patients with diabetic macular oedema. Ophthalmic Res. 2011;46:73–9. doi: 10.1159/000322994 .[bmcophthalmol.biomedcentral.com]

  • Papilledema

    Causes(Unilateral)  Foster kennedy syndrome  Previous unilateral optic atrophy.  Posterior fossa tumor.  Brain abcess.  Subarachnoid haemorrhage.  Optochiasmatic choroiditis[slideshare.net] At a minimum, opening pressure along with glucose, protein, cell count and differential, culture are obtained.[eyewiki.aao.org] Lumbar puncture (to be done after imaging demonstrates no risk for herniation) to document increased ICP and to look for neoplastic, infectious or inflammatory causes.[eyewiki.aao.org]

  • Mulibrey Nanism Syndrome

    The optic nerve and the macula appeared normal while the midperiphery showed focal choroidal hypoplasia with marked atrophy of the retina and of the pigment epithelium.[eurekamag.com] Evolution Growth failure usually progresses during early infancy; after 10 years of age blood fasting glucose levels tend to increase; the diagnosis of Wilms'tumour is usually[atlasgeneticsoncology.org] Fasting glucose concentrations and the 2-h postload glucose concentrations during OGTT increased with advancing age.[diabetes.diabetesjournals.org]

  • Optic Disc Drusen

    Optical coherence tomography (OCT) demonstrated stable focal areas of subretinal fluid OU and macular atrophy OS.[karger.com] With good visual acuity and intact color vision, increased intracranial pressure was suspected.[journals.lww.com] In addition, a thick choroid with large vessels was noted OU.[karger.com]

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