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28 Possible Causes for Focal Keratoderma of Soles, Osteoporosis

  • Growth Hormone Deficiency

    Palmoplantar keratoderma (PPK) is a diverse group of disorders, characterized by thickening of the palms and soles, which are subdivided into focal or diffuse; it can be acquired[ncbi.nlm.nih.gov] The role of anti-RANK ligand (RANKL) antibody for osteoporosis on hepatitis in patients with aGHD is still unknown.[ncbi.nlm.nih.gov] Except for one study, all women received concurrent osteoporosis therapies.[ncbi.nlm.nih.gov]

  • Diffuse Palmoplantar Keratoderma

    […] involving the whole of the palms and soles. [1] : 506-8 [2] : 213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses[like2do.com] Neurocutaneous melanosis sequence Neuroectodermal melanolysosomal disease Nevoid lentiginosis Nevus elasticus Oculo-cerebro-cutaneous syndrome Oculodermal melanocytosis Osteoporosis[icdlist.com] Syndrome Audiologist, Orthopedist, Dentist Refsum Syndrome (Infantile) IRD, Infantile Phytanic Acid Storage Disease 356.3 PEX1, PEX2, PEX26 Facial Dysmorphism, hearing loss, osteoporosis[dermatologyadvisor.com]

  • Epidermolysis Bullosa

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] For some types of EB, the internal mucosa is also affected: nutrition can be compromised, resulting in osteoporosis, and general failure to thrive: quite young children can[debra-international.org] […] include: anemia, cardiomyopathy, syndactyly (fusion of the fingers and toes), renal insufficiency, dysphagia (difficulty swallowing), malnourishment, cancer, constipation, osteoporosis[debra.org]

  • Palmoplantar Keratosis

    […] x-linked dominant condition that begins in early childhood with thick focal keratoderma over the soles and, to a lesser extent, the palms.[en.wikipedia.org] Some authors also reported other findings, such as microphtalmus, intracranial calcification, arachnodactyly, osteoporosis, abnormal hepatic function, renal abnormalities[clinicadavilla.com.br] Vigorous use of water jets should be avoided with fractures, known blood clots, bleeding disorders, severe osteoporosis, open wounds, or during pregnancy.[naturallivingcenter.net]

  • Chest Wall Disorder

    Necrolytic migratory erythema due to glucagonoma Tylosis Tylosis is an autosomal dominant form of focal, non-frictional and nonepidermolytic, palmoplantar keratoderma.[dermnetnz.org] See Causes of Upper Back Pain Many other possible causes of upper back pain exist, such as a thoracic herniated disc, various types of arthritis, and osteoporosis (vertebral[spine-health.com] Clinical guideline for the prevention and treatment of osteoporosis in postmenopausal women and older men. Melbourne: RACGP, 2010. Rosenqusit EWK.[racgp.org.au]

  • Erythema Palmaris Hereditarium

    […] involving the whole of the palms and soles. [1] :506–8 [2] :213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses of[ipfs.io] (see also Osteoporosis) 733.0 [737.41] poliomyelitis (see also Poliomyelitis) 138 [737.41] radiation 737.11 tuberculosis (see also Tuberculosis) 015.0 [737.41] Kümmell's[theodora.com] Ectodermal dysplasia Epidermal acanthosis Cutis laxa Mutism Anhidrosis Curly hair Parakeratosis Neoplasm of the lung Ankylosis Hypergranulosis Lamellar cataract Generalized osteoporosis[mendelian.co]

  • Papillon Lefevre Disease

    Focal keratodermas mainly affect pressure areas. Punctate-type keratodermas result in tiny bumps on the palms and soles.[dermnetnz.org] […] coincides with active periodontal disease. [6] There may be occasional association with hypertension, hyperglycemia, systolic murmurs, retardation of skeletal maturation, osteoporosis[ijdvl.com] […] from time to time, with various associations such as liver abscess, ectopic intracranial calcification, hyperhidrosis, hypertension, hyperglycemia, thyroid enlargement, osteoporosis[idoj.in]

  • Evan's Syndrome

    Clinical description Tylosis (hyperkeratosis palmaris et plantaris) is a focal, non-epidermolytic form of keratoderma characterised by areas of yellowish thickened plaques[ojrd.biomedcentral.com] These include five mini-strokes, heart failure, osteoporosis and diabetes. Life has got better but in a sense he feels he has only been give a stay of execution.[walesonline.co.uk] […] restricted to areas of weight bearing and/or friction on the palms and soles [ 5, 9 ].[ojrd.biomedcentral.com]

  • Epidermolysis Bullosa Simplex

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] These supplements may help prevent osteoporosis (thinning bones).[medlineplus.gov] Secondary consequences of the disease include malnutrition with subsequent growth slowing, anemia, constipation, osteopenia, osteoporosis, and dilated cardiomyopathy.[aocd.org]

  • Pachyonychia Congenita

    Fig 2: Showing focal keratoderma on soles. Fig 3: Showing pachyonychia in hands and feet. Fig 4: Showing leukoplakia on tongue and angular cheilitis of mouth.[edoj.org.eg] Vigorous use of water jets should be avoided with fractures, known blood clots, bleeding disorders, severe osteoporosis, open wounds, or during pregnancy.[simplygoodnaturalfoods.com] The predominant features common to both types are thick nails (hypertrophic nail dystrophy), thick skin on the palms and soles (focal palmoplantar keratoderma) and a white[metrohealth.net]

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