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34 Possible Causes for Focal Keratoderma of Soles, Plantar Hyperkeratosis

  • Papillon Lefevre Disease

    Focal keratodermas mainly affect pressure areas. Punctate-type keratodermas result in tiny bumps on the palms and soles.[dermnetnz.org] Papillon-Lefèvre syndrome (PLS) is a rare autosomal disorder characterized by severe periodontitis and palmar plantar hyperkeratosis (PPK).[ncbi.nlm.nih.gov] hyperkeratosis periodontal disease Descripción : The connection between palmar plantar hyperkeratosis and severe periodontal disease was first reported in 1924 by Papillon[189.203.43.34]

  • Pachyonychia Congenita

    Fig 2: Showing focal keratoderma on soles. Fig 3: Showing pachyonychia in hands and feet. Fig 4: Showing leukoplakia on tongue and angular cheilitis of mouth.[edoj.org.eg] Citation: Higgins E, Capra M, Schwartz ME, Smith FJD, McLean WHI, Irvine AD, Resolution of the plantar hyperkeratosis of pachyonychia congenita during chemotherapy for Ewing[tara.tcd.ie] The predominant features common to both types are thick nails (hypertrophic nail dystrophy), thick skin on the palms and soles (focal palmoplantar keratoderma) and a white[metrohealth.net]

  • Palmoplantar Keratosis

    […] x-linked dominant condition that begins in early childhood with thick focal keratoderma over the soles and, to a lesser extent, the palms.[en.wikipedia.org] Thomas, SE, Dykes, PJ, Marks, R: Plantar hyperkeratosis: A study of callosities and normal plantar skin. J. Invest. Dermatol. 85: 394 – 397, 1985.[doi.org] Apocrine hidrocystomas of the lids, hypodontia, palmar-plantar hyperkeratosis, and onychodystrophy: a new variant of ectodermal dysplasia. Arch Ophthal. 1986;104:1811-3.[nutritionhouse.com]

  • Howell-Evans Syndrome

    Palmoplantar keratoderma (PPK) is a complex group of hereditary syndromes that have been classified into diffuse, punctate, and focal forms according to the pattern of hyperkeratosis[ncbi.nlm.nih.gov] Int J Dermatol 42(6):461-463 Nomori H, Horio H, Iga R, Fuyuno G, Kobayashi R, Morinaga S (1996) Squamous cell carcinoma of the lung associated with palmo-plantar hyperkeratosis[research.omicsgroup.org] Focal keratodermas are palmoplantar keratodermas (PPK) that involve only some areas of the palms or soles, usually over pressure points.[dermnetnz.org]

  • Jadassohn-Lewandowsky Syndrome

    Fig 2: Showing focal keratoderma on soles. Fig 3: Showing pachyonychia in hands and feet. Fig 4: Showing leukoplakia on tongue and angular cheilitis of mouth.[edoj.org.eg] She had a scrotal tongue with leucokeratotic areas, Blister formation, Plantar hyperkeratosis, palmoplantar hyperhidrosis and Dental cavities since childhood [8] .[gulfdoctor.net] Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles (palmoplantar hyperkeratosis or keratoderma , particularly[dermnetnz.org]

  • Diffuse Palmoplantar Keratoderma

    […] involving the whole of the palms and soles. [1] : 506-8 [2] : 213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses[like2do.com] CONSUMERS: Click here for the Consumer Version Topic Resources Palmoplantar keratodermas are rare inherited disorders characterized by palmar and plantar hyperkeratosis.[merckmanuals.com] hyperkeratosis, e.g. of weight-bearing skin; severe forms are associated with constricting digital bands, leading to autoamputation; treated by regular hyperkeratosis reduction[medical-dictionary.thefreedictionary.com]

  • Epidermolysis Bullosa Simplex

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] A 22-year-old Japanese woman with Koebner epidermolysis bullosa simplex presented with severe palmo-plantar hyperkeratosis.[ncbi.nlm.nih.gov] […] as "Koebner variant of generalized epidermolysis bullosa simplex", presents at birth to early infancy with a predilection for the hands, feet, and extremities, and palmar-plantar[en.wikipedia.org]

  • Erythema Palmaris Hereditarium

    […] involving the whole of the palms and soles. [1] :506–8 [2] :213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses of[ipfs.io] Consultation of a dermatologist was taken for evaluation of hyperkeratosis of the palmar and plantar surfaces.[e-ijd.org] […] involving the whole of the palms and soles. [1] : 506–8 [2] : 213 Focal [ edit ] Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact[en.wikipedia.org]

  • Epidermolysis Bullosa Simplex Type Kobner

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] TY - JOUR T1 - Severe palmo-plantar hyperkeratosis in Koebner epidermolysis bullosa simplex.[unboundmedicine.com] The frequency of milia, mild atrophic scarring, focal plantar hyperkeratosis and nail dystrophy is intermediate between that of localized EBS and EBS-DM (see these terms),[orpha.net]

  • Evan's Syndrome

    Clinical description Tylosis (hyperkeratosis palmaris et plantaris) is a focal, non-epidermolytic form of keratoderma characterised by areas of yellowish thickened plaques[ojrd.biomedcentral.com] – focal PPK, oral hyperkeratosis, subungual hyperkeratosis (mutation keratin 16) Pachyonychia congenita type I (Jadassohn-Lewandowsky syndrome) – AD, congenital pachyonychia[visualdx.com] hyperkeratosis and oesophageal lesions, and mutations in RHBDF2.[ojrd.biomedcentral.com]

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