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13 Possible Causes for Focal Keratoderma of Soles, Sleep Disturbance

  • Growth Hormone Deficiency

    Palmoplantar keratoderma (PPK) is a diverse group of disorders, characterized by thickening of the palms and soles, which are subdivided into focal or diffuse; it can be acquired[ncbi.nlm.nih.gov] In adults, symptoms include: Decreased energy Increase in fat and decrease in lean muscle mass Difficulty exercising Osteoporosis Sleep disturbance Skin changes (fine lines[ucsfhealth.org] In adults symptoms include: decreased energy a feeling of social isolation increase in fat and decrease in lean muscle mass poor exercise tolerance osteoporosis sleep disturbance[ccpd.ucsf.edu]

  • Ovarian Cyst

    Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles ( palmoplantar hyperkeratosis or keratoderma, particularly[dermnetnz.org] The Prakruti of the patient is Pitta vata with amaliptajivha (coated tongue), alpaaharashakti (diminished appetite), alpanidra (disturbed sleep) and mrudukosta (smooth bowel[omicsonline.org] focal palmoplantar keratoderma ), resulting in difficulty walking Focal palmoplantar keratoderma may be the only feature of pachyonychia congenital in patients with mutations[dermnetnz.org]

  • Upper Airway Obstruction

    Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles (palmoplantar hyperkeratosis or keratoderma, particularly[dermnetnz.org] When the tracheostomy was occluded 1 year later, periodic apnea and sleep disturbances recurred.[annals.org] […] apnoea stroke Abbreviations: BP, blood pressure; BMI, body mass index; IQR, interquartile range; OSA, obstructive sleep apnoea; RDI, respiratory disturbance index; UAO, upper[clinsci.org]

  • Erythema Palmaris Hereditarium

    […] involving the whole of the palms and soles. [1] :506–8 [2] :213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses of[ipfs.io] 2019年1月 乾癬における睡眠障害:症例対照研究 Sleep disturbance in psoriasis: a case‐controlled study clinically amyopathic dermatomyositis(CADM)の成人患者の治療:系統的レビュー - Piguet Treatment of clinically[maruho.co.jp] […] involving the whole of the palms and soles. [1] : 506–8 [2] : 213 Focal [ edit ] Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact[en.wikipedia.org]

  • Evan's Syndrome

    Clinical description Tylosis (hyperkeratosis palmaris et plantaris) is a focal, non-epidermolytic form of keratoderma characterised by areas of yellowish thickened plaques[ojrd.biomedcentral.com] Studies have shown that amalgam fillings are linked to gastrointestinal problems, sleep disturbances, concentration problems, memory disturbances, lack of initiative, restlessness[vgirlnatural.wordpress.com] […] restricted to areas of weight bearing and/or friction on the palms and soles [ 5, 9 ].[ojrd.biomedcentral.com]

  • Chest Wall Disorder

    Necrolytic migratory erythema due to glucagonoma Tylosis Tylosis is an autosomal dominant form of focal, non-frictional and nonepidermolytic, palmoplantar keratoderma.[dermnetnz.org] disturbance and fatigue, with widespread pain and trigger points suggest fibromyalgia.[racgp.org.au] It involves more than 50% of the surface of palms and soles.[dermnetnz.org]

  • Pityriasis Rubra Pilaris

    There was a waxy orange keratoderma affecting the palms and soles with associated painful fissuring ( figure 3 ).[casereports.bmj.com] Pruritus, pain, and sleep disturbance are common with this disorder.[rarediseases.org] Histopathology of involved skin showed focal parakeratosis and orthokeratosis alternating in both horizontal and vertical directions with an underlying perivascular inflammatory[casereports.bmj.com]

  • Lamellar Ichthyosis

    […] and soles ( Lucker et al., 1994 ).For a discussion of phenotypic and genetic heterogeneity of palmoplantar keratoderma, see epidermolytic PPK ( OMIM ).[mendelian.co] - Blood sugar will elevate - Hyperactivity - Difficulty sleeping - Hyperphagia - Disturbances in menstrual cycle - Difficult healing How do you do a prednisone taper?[flashcardbook.com] (PPK) is a complex group of hereditary syndromes that have been classified into diffuse, punctate, and focal forms according to the pattern of hyperkeratosis on the palms[mendelian.co]

  • Epidermolysis Bullosa Pruriginosa

    However, it is particularly characteristic for blistering on the palms and soles to be succeeded by focal keratoderma, although this is also seen, usually to a lesser degree[plasticsurgerykey.com] The intense pruritus was socially embarrassing and often disturbing sleep.[ispub.com]

  • Neu-Laxova Syndrome Type 2

    focal keratoderma over the soles.[plasticsurgerykey.com] The sleep disturbance is linked to an abnormal circadian secretion pattern of melatonin.[icd10data.com] Focal areas of thickening, sometimes tender, may develop on the palms and soles. 595 Some have an autosomal recessive inheritance.[plasticsurgerykey.com]

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